Ta yaya karin kayan abinci na gina jiki yana ba da bege ga matan da ke fama da PCOS.
Berberine wani karin kari ne da aka yi amfani da ita a cikin shekaru dubban shekaru a kasar Sin a matsayin magani ga ciwon sukari, cututtuka, da rashin haihuwa. Yanzu bincike yana farawa ne don bincika amfani da shi a cikin mata tare da ciwon maganin polycystic ovary ( PCOS ) har zuwa yanzu, sakamakon yana da ƙarfafa.
Menene Berberine?
Berberine wani alkaloid ne wanda aka samo daga ƙwayoyin Sinanci irin su hydrastis cacadensis (goldenseal), berberis aquifolium (saran inabi), berberis vulgaris (barberry), berberis aristata (turmeric itace), da kuma coptidis rhizome (huanglian).
Ana iya ɗauka a matsayin capsule ko a cikin ruwa.
An nuna shinge don taimakawa tare da inganta yanayin kewayon yanayi, tare da amfanin kamar waɗannan:
- Inganta gwajin insulin
- Ana rage testosterone
- Rage kuraje
- Ya rage matakan cholesterol
- Inganta cututtuka mai cututtukan masu ciwo marasa barasa
- Inganta ciki da haihuwa
- Yana bayar da tallafi na rigakafi
- Bayar da amfani da magunguna
- Ya rage yawan hawan jini
- Yarda da asarar nauyi da kuma asarar mai
- Yin maganin ciwon daji
Berberine da PCOS
Berberine na iya ba da dama ga mata da PCOS ciki har da inganta ingantaccen haihuwa, taimakawa tare da asarar nauyi, da kuma rage haɗarin rikitarwa na rayuwa wanda ke haɗuwa da ciwo irin su cututtukan sukari 2, high cholesterol, da kuma ciwon hanta.
Sensitizer mai insulin mai karfi
Wataƙila babban aikin da berberine yake yi shi ne mai hangen nesa na insulin. Mata da PCOS sun nuna alamun insulin mafi girma idan aka kwatanta da mata masu nauyin nauyin ba tare da yanayin ba.
Metformin wani magani ne mai maganin insulin wanda aka saba wa mata da PCOS don taimakawa wajen sarrafa insulin da glucose. Duk da haka, yawancin matan da ke tare da PCOS sun sami sakamako na illa gastrointestinal na metformin irin su zawo, tashin zuciya, da kuma ciki mai ciki. An kuma nuna alamar ƙwayar metformin na tsawon lokaci don shafan bitamin B12 .
An nuna cewa Berberine ya inganta haɓakar insulin a irin wannan hanyar zuwa metformin. Berberine inganta ingantaccen siginar insulin ta hanyar haɓaka glucose amfani ta hanyar kunna hanyar haɓakar haɓakar haɓakar ƙarancin AMP.
Amfanin berberine an kwatanta da metformin a cikin mata da PCOS. A cikin wani binciken da aka buga a cikin Jarida ta Turai na Endocrinology , Wei da abokan aiki sun zaɓi 89 mata da PCOS don su samu ko dai berberine (500 MG, sau uku a rana), metformin (500 mg, sau uku a rana), ko wuribo na 3 watanni.
Dukan mata sun umurce su da wani mai gina jiki don rage yawan ciwon sukari da fatsari. Ba a samar da calorie ba. Ana kuma umarci mata su yi amfani da minti 30 a kowace rana tare da matsin motsa jiki.
Bayan watanni uku na jiyya, matan da ke da PCOS da suka dauki berberine sun ga yawan raguwa a asarar jiki kamar yadda metformin ko placebo ya fi. Berberine ya saukar da insulin da glucose matakan da metformin.
Mata tare da PCOS wadanda suka dauki berberine sun ga raguwa mai yawa a cikin dukan ƙwayar cholesterol , LDL (ƙananan cholesterol matuka), da kuma triglycerides da mahimmancin cigaba a cikin HDL (darajar ƙwayar cholesterol), fiye da shan metformin ko placebo.
Bugu da ƙari, shan berberine ya sauke matakan testosterone duka daidai da na metformin.
Inganta haihuwa
Duk da yake berberine yana nuna amfanoni wajen inganta rikitarwa na tsarin PCOS, yana iya inganta ƙwayar haihuwa . A cikin binciken gwajin gwagwarmaya, an baiwa mata 98 da ke da PCOS berberine. Ovulation ya inganta ta hanyar kashi 25 cikin 100 bayan watanni 4 na shan berberine.
Wani binciken da aka buga a cikin Clinical Endocrinology ya nuna cewa mata da PCOS wadanda aka zaba don su dauki berberine, suna da girma a ciki fiye da metformin ko placebo kuma tare da raƙuman sakamako a yayin da aka ɗauki makonni 12 kafin a yi amfani da IVF.
Taimakawa da Asarar Rashin
Kusan kowane mata da ke da PCOS zai iya gaya maka cewa rasa nauyi yana da wuya ga waɗanda suke da yanayin. Kuma asarar nauyi shine mafi wuya ga dalilai da yawa ciki har da haɓaka insulin ƙaruwa, ƙwarewa ga ƙwayoyin carbohydrates, da ka'idojin ci ci.
Berberine na iya ba da bege ga mata da PCOS wadanda ke gwagwarmaya da nauyin su. An nuna cewa Berberine ya rage yawancin abincin da ke ciwo da kwayar cutar hormone leptin . Berberine ya nuna cewa yana da tasiri wajen taimakawa tare da nauyin nauyi da hasara mai jiki ta hanyar hana ƙin enzyme lipoprotein lipase, wanda ke da alhakin ajiyar ajiya. Sakamakon lura da shan berberine a mafi yawancin karatu shine asarar nauyi, musamman ma a tsakiyar ɓangaren jiki, da kuma saukar da matakan rarraba jiki (BMI).
Rage Fatty Liver
Mata da PCOS suna fuskantar haɗari na samun ciwon hanta mai haɗari saboda dangantaka da matakan insulin. An nuna Berberine wani zaɓi mai inganci don rage hanta mai hasara. Binciken ka'idojin gwaje-gwaje guda shida da suka hada da mutane 500, sun gano cewa berberine yana rage yawan hanta mai haɗari a waɗanda ke da cutar ciwon hanta (NAFLD). Berberine ya saukar da TG da hanta ayyukan enzymes, kuma inganta overall hanta aiki. An gano cewa berberine yana inganta NAFLD ta hana ƙwayar hanta mai ginawa da inganta ingantaccen abuwan hawan acid a cikin tsoka mai ƙumshi.
Abin da ya sani game da Shan Berberine
Yawanci, berberine yana da haƙuri amma yana iya haifar da illa gastrointestinal masu haɗari ciki har da tashin zuciya da ƙyama, musamman idan aka yi amfani da su a cikin asurai.
Sashin magani na berberine don inganta insulin da sauran amfanin kiwon lafiyar da aka tabbatar yawan 500 mg, sau uku a kowace rana (kama da na metformin dosing). Don kauce wa GI tada, zai iya zama mafi kyau a yi amfani da shi a hankali har zuwa mita 1,500 a kowace rana ta hanyar shan mintuna 500 na mako na farko, ƙara ƙarin 500m na biyu na mako, har sai kun isa 1,500mg ta mako uku.
Ba a yi amfani da Berberine don amfani da dogon lokaci ba. Babu bayanai da ke samuwa game da lafiyar berberine daga matasan mata ko a lokacin da aka fara ciki. Ba a ba da shawarar Berberine a lokacin haihuwa ko lactation ba.
Berberine na iya canza yanayin hanta na wasu magunguna. Ana ba da shawarar kulawa idan ka ɗauki wasu magungunan magani kamar su antidepressants , MAAI masu hanawa, masu zubar da jini, da beta-blockers. Kulawa akai-akai game da gwajin aikin hanta yana da shawarar ga wadanda ke shan berberine. Tun da yake berberine shine insulin-sensitizer, zai iya haifar da ƙananan jini, musamman idan an hade shi tare da wasu magungunan insulin-lowering kamar metformin ko kari kamar inositol ko n-acetylcysteine. Yi shawara tare da likitanku kafin shan berberine.
> Sources:
> An Y, Sun Z, Zhang Y, Liu B, Guan Y, Lu M. Yin amfani da berberine ga mata tare da ciwon maganin polycystic ovary ɗauke da tsarin IVF. Clin Endocrinol (Oxf). 2014 Mar; 80 (3): 425-31.
> Chang X et al. Labarin lipid na ilimin warkewa na berberine a cikin marasa lafiya tare da cututtukan hanta mai cutar marasa ciki .J Transl Med. 2016 Sep 15; 14: 266.
> Lin L et al. Nazarin Kwalejin Lantarki na Ƙarshe na Halitta na Berberine a kan Harshen Menstual, Ƙimar Ovulation, Hormonal da Metabolic Bayanan martaba a cikin 'Yan matan Sin da ke da ƙwayar cutar ta Polycystic. PLoS Daya. 2015; 10 (12): e0144072.
> Wei W, et al. Nazarin binciken asibiti game da ɗan gajeren lokaci na berberine idan aka kwatanta da metformin a kan halaye na al'ada na mata tare da ciwon maganin polycystic ovary. Eur J Endocrinol. 2012 Janairu 166 (1): 99-105.
> Yang J et al. Berberine inganta ingantaccen insulin ta hanyar hana gine-gizen kayan sha da kuma daidaitawa da bayanin adipokines a cikin adadin mutane da kuma ciwon marasa lafiya. Ƙididdiga Tabbatar Da Sharuɗɗa Madauwari Mako. 2012: 363845.