Kamar yadda kimiyyar likita ta fahimci game da ciwo na fibromyalgia (FMS), kamfanonin kamfanonin suna racing don samun FDA don amincewa da karin maganin fibromyalgia. Doctors sun rubuta duka magungunan da aka amince da su da magunguna masu magunguna don sun sami su zama tasiri.
FDA-ANYA FIBROMYALGIA KASHI
Lyrica (pregabalin) : A watan Yunin 2007, Lyrica ya zama magungunan fibromyalgia na farko na FDA.
A cikin gwaje-gwaje na asibiti , mutanen da ke tare da FMS sun nuna gagarumar cigaba a cikin ciwo, barci, gajiya, da kuma rayuwa mai kyau . Kayan aikin Pfizer, Lyrica kuma an yarda da shi don magance ciwon sukari neuropathy da ciwon ƙananan ƙwayar cuta . Ana amfani da shi, a hade tare da sauran kwayoyi, don hana tsoma baki a cikin tsofaffi marasa lafiya.
Yana iya zama m, amma Pfizer ba daidai ya tabbata dalilin da yasa Lyrica ke aiki ba. Wannan shi ne abin da ya ce a shafin intanet na FDA:
Kayan aikin ba a san shi ba, amma akwai wasu bayanan da ke nuna cewa yana da tasiri a kan sakin neurotransmitters a kwakwalwa. Neurotransmitters sune sunadarai a cikin kwakwalwa wanda ke watsa siginonin daga wani neuron zuwa wani.
Cymbalta (duloxetine) : FDA ta amince da Cymbalta a matsayin likitan fibromyalgia a watan Yunin 2008. Cymbalta an classified shi ne a matsayin SNRI, ko kuma mai ba da izini na rerotonin-norepinephrine. Serotonin da norepinephrine duka biyu ne waɗanda ba su da raguwa a cikin mutane da fibromyalgia.
SNRIs sa yawancin su zuwa kwakwalwa.
Cymbalta ta kasance FDA ta amince da ita don magance matsalolin da ciwon sukari neuropathy .
Savella (Milnacipran) : Sabbin magungunan miyagun ƙwayoyi zuwa kasuwar Amurka, Savella ya amince da shi a watan Janairu 2009 a matsayin magani na fibromyalgia. Kamfanin Forest Laboratories, Inc. da Cypress Bioscience, Inc., sunyi amfani da su, Savella mai maganin antidepressant ne kamar Cymbalta sai dai shi ne farkon magani a cikin kundin don bunkasa norepinephrine fiye da serotonin.
Sabuwar Maganin Drug , wanda aka yi a watan Disamba na 2007, ya hada da bayanai daga gwajin gwaji na biyu na Phase III wanda ya shafi fiye da marasa lafiya 2,000. Kamfanin ya ce bayanan ya nuna Savella ya fi tasiri fiye da wuribo kuma an yarda da shi. Babu mutuwar kuma mafi yawancin cututtukan da aka kwatanta a matsayin m zuwa matsakaici.
An sayar da Milnacipran a Turai a karkashin sunayen Dalcipran da Ixel. An kasance a kasuwa har tsawon shekaru goma kuma an yarda da shi a cikin kasashe fiye da 50.
Neman BABI NA FIBROMYALGIA
JZP-6 (sodium oxybate) : Gwajin gwaji na JZP-6 (mai aiki a cikin Xyrem) ya nuna cewa ya inganta ingantaccen barci kuma rage yawan ciwo a cikin marasa lafiya na fibromyalgia . JZP-6 yana da mawuyacin tsarin kulawa mai mahimmanci kuma ana zaton zai taimaka wa mai haƙuri ya sami zurfin mataki 3 da mataki 4 na barci. An gabatar da gwaji na gwaji na farko na III na asibiti a cikin watan Satumba na 2008 da Jazz Pharmaceuticals sun gabatar da takardar Drug Application zuwa FDA a cikin watan Disambar 2009. Sakamako na karin gwajin Phase III suna jiran, amma kamfanin ya ce binciken da aka goyi baya a baya sakamako mai kyau.
Xyrem ne FDA-yarda don cataplexy (asarar kwatsam na karfin tsoka) da kuma barci mai tsanani a rana a marasa lafiya da narcolepsy.
Lura: Saboda yiwuwar cin zarafinsa, Xyrem wani jigilar kayan aiki ne mai sauƙi.
Adeona Pharmaceuticals na fatan samun Effirma a Amurka a karo na farko, kuma a cikin watan Afrilu 2008 kamfanin ya sanar da cewa FDA ta ba shi Sashin Sabuwar Magunguna. Wannan yana bada izinin kamfanin don gudanar da gwagwarmaya, mai makafi guda biyu, mai gudanarwa na Phase II na gwaji don Effirma a matsayin magani na FMS.
An amince da jigilar ta baka a Turai domin fiye da shekaru 25. A nan, ana amfani dasu don maganin ciwo daga magunguna masu yawa, ciki har da tiyata , ciwon daji, cututtuka da hanta.
Har ila yau, Adeona yana fatan ya nuna cewa yana magance fiye da lalacewar FMS, amma inganta yanayi, gajiya, matsalolin da zafin hankali, tashin hankali da kuma aiki na gaba.
WANNAN FIBROMYALGIA DRUGS
Magungunan antidepressants: Magunguna suna ɗauke da matakan wasu sunadarai a cikin kwakwalwa, ciki har da serotonin neurotransmitter and hormone norepinephrine - duka biyu suna da rauni a cikin mutanen da ke ciki ko FMS.
- Mawallafi Masu Dubu Biyu: Wannan kundin ya haɗa da Cymbalta da Savella. Wasu misalan wadannan kwayoyi sune: venlafaxine da nefazodone.
- Tricyclic Antidepressants : Idan aka dauke da dare, waɗannan kwayoyi zasu iya taimakawa mutanen da ke da FMS samun barci mai kyau. Suna kuma kara yawan sakamakon ciwon endorphin-kashewa da kuma taimakawa wajen shawo kan tsokoki . Wasu magungunan antidepressic da aka saba amfani dashi don bi da FMS sun hada da: amitriptyline, doxepin da nortriptyline.
- Masu amfani da maganin raunin maganin Serotonin Reuptake ( SSRI s): Wadannan kwayoyi sun sami kwakwalwa don saki mafi yawan sifa, wanda ke taimakawa wajen daidaita barci, kuma wasu lokuta sukan taimaka wa mutanen da ke fama da rashin lafiya da kuma samun mafita daga wasu cututtuka. Duk da haka, zasu iya tsoma baki tare da barci. Misalan SSRIs sune: fluoxetine, paroxetine da sertraline.
Duk magunguna da aka jera a nan suna da tasiri mai tasiri kuma zai iya haifar da matsalolin lafiya idan ka daina ɗaukar su ba zato ba tsammani. Yana da muhimmanci a zauna tare da likitan ku don tattauna duk wani matsalolin ko canji.
KASHI / NARCOTICS A matsayin FIBROMYALGIA TREATMENTS
Nazarin ya nuna cewa yawancin marasa lafiya ba su da tasiri akan cutar ta FMS. Duk da haka, mutane da yawa sun bayar da rahoton cewa suna taimakon, kuma wa] annan magungunan suna wajabta shi.
Masu bincike / narcotics sun hada da:
- Vicodin (hydrocodone acetaminophen)
- Percocet (oxycodone acetaminophen)
- OxyContin (oxycodone)
Don magance tsoratar da cin zarafi da cin zarafi, Cibiyar Harkokin Ciniki ta Amirka ta ba da takaddama ga likitoci.
RAYUWA DRUG & NASIHIYA RUKUNWA
- Tabbatar likita ya san game da dukkan kwayoyi da kayan abinci mai gina jiki da kake dauka. Yi magana da likitanku ko likitan magunguna game da illa masu lalacewa da hulɗar saɓani mara kyau.
- Don ganin jerin jerin abubuwan da ke cikin tasiri da kuma hulɗar miyagun ƙwayoyi , tare da kuri'a na wasu bayanai, ga Drugs.com ko RxList.com.
- Idan kana da halayen halayen likitanci, to tabbata ka bayar da rahoto ta hanyar FDA Safety Information da Shirye-shiryen Rahoton Abubuwan Taɓaɓɓe.
Source:
NIH Publication NO. 04-5326.
Cibiyar Abinci da Drug. "Rayuwa da Fibromyalgia"