Kwayoyin mastuna suna samuwa a cikin jikin haɗin kai a jikin jikin mu a matsayin ɓangare na tsarinmu na rigakafi. Kwayoyin mastuna sune mahimmanci a cikin jikin jikinmu wanda ke hulɗa da duniyarmu, irin su waɗanda suka samo a kan fata da kuma cikin sassan mu na numfashi. Kwayoyin mast can kuma za a iya samuwa a cikin kwayoyin halitta da kuma kayan jikin mu na sassan jiki da kuma juyayi.
Mast cells suna da muhimmiyar rawa wajen kare lafiyarmu ta hanyar samar da layin kare kan pathogens .
Ayyukan Kwayoyin Mast
Dangane da yaduwa ga kamfanonin da aka sani, ƙwayoyin mast sun sanya mummunar amsawa ga masu ƙwaƙwalwa na waje, irin su germs, ƙwayoyin ƙwayoyin cuta, da kuma ɓangaren ƙwayoyin cuta. Kwayoyin Mast suna da damar su kashe rayukan kwayoyin halitta ko kuma su daɗa kayan aiki da saki kayan da zasu halakar da pathogen.
Kwayoyin mastuna suna taka muhimmiyar rawa wajen kunna maganin rashin lafiyar. Lokacin da mutum yana da ciwon haɗari, ƙwayoyin mast suna amsawa ga magungunan marasa lahani kamar suna barazanar.
Bugu da ƙari, ga tsarin lafiyar su da ƙarancin tsarin, kwayoyin mast ma sun shiga cikin:
- Tsare-tsaren jinin jini da aikin aiki na bronchial
- Raunin warkar
- Samar da sabon jini
- Daidaita aiki na sel a cikin jiki
- Dokar bunkasa kashi
Mast Cell Response
Domin amsa gagarumar barazanar, kwayoyin mastuna suna haifar da saki da dama na masu gwaji, irin su histamine da serotonin, da kuma enzymes irin su cytokines da proteases.
Wadannan abubuwa sun haifar da tsayayyen lokaci mai tsawo da kuma tsawon lokaci. Bari mu dubi wasu daga cikin mahimman ƙwayoyin mast cell.
Amsar ginsrointestinal fili
Lokacin da muka ci abin da ake zaton zai zama cutarwa, kwayoyin mast za su haifar da amsa wanda yana da sakamakon wadannan:
- Ƙara yawan kyawawan ruwa
- Ƙara ƙwayar tsoka a cikin tsarin narkewa (na iya haifar da vomiting ko zawo)
- Matsar da kwayoyi masu sauri cikin sauri
Wadannan ayyuka suna da mahimmanci, shin ba? Jiki yana ƙoƙari ya kawar da abin da ya gane zai zama mai cutarwa kamar yadda ya iya.
Kwayoyin mastuna suna da muhimmiyar gudummawa wajen inganta daidaitattun kwayoyin kwayoyin halitta wanda ke samar da furen mu. Yayin da aka samu suturar mast a cikin rufin mu, suna taka muhimmiyar rawa wajen lalatarwa da kare jikin mu daga dukkan kwayoyin cuta.
Amsar respiratory tract
Ana gano sassan mast a cikin rufin sassan mu na numfashi. Dangane da antigen, yawanci wanda aka shafe shi, ƙwayoyin mast za su haifar da amsawar ba tare da amsa ba:
- Ƙaddamar da hanyoyi
- Raguwa
- Coughing
- Ƙara yawan samar da ƙuduri
Kamar yadda kake gani daga abubuwan da ke sama, ba abin mamaki bane cewa sassan mast suna da hannu sosai a cikin bayyanar cututtukan fuka .
Maganin fata
Wataƙila ku san saba da ra'ayi cewa wasu mutane suna ganin asibitoci ko raguwa saboda amsa cin abinci. Wannan yana faruwa saboda antigens a cikin abinci shigar da jini ta hanyar GI fili. Yayinda suke tafiya cikin jikin su sun hadu da kwayoyin mast da aka gano a cikin takalma na fata.
Hanyoyin kumburi na waɗannan kwayoyin mast ɗin zasu iya haifar da kumburi, amya, rashes da kuma karin matsalar ƙwayar cuta ta nakasassu (eczema).
Mast Cells da kuma Abincin Nishaji
Saboda gaskiyar cewa kwayoyin mastuna suna siffanta fili na hanji, kuma sun ba da sakamakon su dangane da amsawar ba tare da amsawa ba, an sanya kwayoyin mast a cikin rawar da take takawa a cikin wadannan cututtuka biyu na gastrointestinal:
Hanyoyin da kwayoyin mast za su iya haifar da wadannan cututtuka:
- Hanyar tafiya mai sauri (sakamakon sakamakon zawo)
- Ƙara ƙwayar ruwa a cikin babban hanji (kuma yana taimakawa wajen zawo)
Abin sha'awa, ana iya rinjayar ayyukan ƙwayoyin mast da yawan damuwa da kake ciki. Akwai alamun sadarwa guda biyu tsakanin sassan jikinka mai juyayi da ƙwayoyin mast. Sabili da haka ayyuka na ƙwayoyin mast na iya taka muhimmiyar rawa a cikin gaskiyar cewa zafin jiki na IBS zai kara tsanantawa ta matsalolin waje.
Nazarin ya nuna cewa akwai yawan ƙwayoyin mast da yawa a cikin rufin intestinal na mutanen da ke da IBS. Masana kimiyya basu riga sun sani ba game da dalilin da yasa hakan yake, amma yana da matukar farin ciki na bincike yayin da zai haifar da yiwuwar ci gaban sababbin jiyya don maganin.
Sources:
Krystel-Whittemore, M. "Mast Cell: Babbar Jagora Mai Kyau" Fassara a Immunology 2015 6: 620.
Philpott, H., Gibson, P. & Thien, F. "Ciwo mai rashin tausayi na rashin jin dadi - Kwayar cututtuka da ke dauke da kwayoyin mast" Asiya Asiya ta Yammacin Turai 2011 1: 36-42.
Ramsay, D., et. al. "Mast Cells in Gastrointestinal Disease" Gastroenterology & Hepatology 2010 6: 772-777.
Urb, M. & Sheppard, D. "Matsayi na Mast Cells a cikin Tsaron da Pathogens" PLoS Pathogens 2012 8: e1002619.