Kuna iya samun matakan cholesterol masu girma ƙara yawan hadarin ku?
Kamar sauran dalilai, irin su cutar hawan jini, high cholesterol na iya kara yawan hadarin ka.
Cholesterol wani abu ne wanda yake taimakawa wajen gina gurasar, wanda ake kira plaques, a cikin jini. Plaques zasu iya tarawa a cikin suturar jini, wanda zai ba da oxygen zuwa zuciya, da kuma a cikin carotid arteries, wanda ke samar da oxygen zuwa kwakwalwa.
Tare da cutar hawan jini , da ciwon sukari , shan taba, da kuma kiba, ƙananan ƙwayoyin cholesterol an kafa su a matsayin wani abu mai hadari ga cututtukan zuciya na zuciya ga maza da mata. Kamar sauran dalilai, cholesterol ma damuwa ne game da bugun jini .
Kamar dai yadda ciwon zuciya zai iya faruwa lokacin da ɗayan maganin jinin na zuciya ya rabu da kuma an katange, fashewa ko "kwakwalwar ƙwaƙwalwa," zai iya haifar da haɗuwa da maganin da ke samar da oxygen zuwa kwakwalwa. Duk da haka, binciken da aka yi a wannan yanki ya ba da gudummawar ra'ayi akan tasirin cholesterol a cikin bugun jini.
Cholesterol da Cutar - Labari mai rikitarwa
Hadin da ke tsakanin cholesterol da bugun jini yana da rikitarwa saboda dangantakarsu ta bambanta ne bisa irin irin ciwon bugun jini da kuma nau'in cholesterol.
Akwai manyan nau'i biyu na fashewa. Mafi yawan bugun jini, fashewar ischemic , ya haifar da tawayar jini. Abubuwan haɗari ga cututtuka na ƙishirwa, ciki har da ƙananan cholesterol, suna da irin wannan cututtukan zuciya.
Sauran magungunan ƙwayar cuta, fashewar jini , yana haifar da rushewar jirgi mai jini, wanda ya shiga cikin kwakwalwa. Duk da haka, saboda wannan irin ciwon bugun jini, ƙananan cholesterol yana da ƙarfin rage yawan hadarin bugun jini. Don bugun jini na ischemic, a gefe guda, ƙananan ƙwayoyin cholesterol wani abu ne mai hadari - ba babban abu ba, watakila, amma tabbas lamari ne mai hadari.
Wani muhimmiyar wahala: Ba dukkanin cholesterol ba ne. Daban-daban na cholesterol na iya samun tasiri daban a jiki. LDL shine "mummunar cholesterol" dangane da yiwuwar cutar da zuciya da kwakwalwa kuma yana da babbar mahimmanci ga bunkasa takarda. Yawan matakin LDL cholesterol fiye da miliyon 130 a kowace deciliter (MGM / DL) ana danganta shi da haɗakar ƙwayar cutar bugun jini.
HDL , a gefe guda, shine "mai kyau cholesterol." Matsakanin HDL fiye da 35 MG / dL kare kariya daga cututtuka ta hanyar taimakawa LDL zuwa hanta kuma daga jini kuma ta hanyar taimakawa wajen daidaita batutuwan da ke ciki. Matsakanin mafi girma na HDL sun ci gaba da ƙara kariya, tare da mafi girma yawan ƙimar da HDL ya ba su akan 60 mg / dL. A gefe guda, matakan HDL da ke ƙasa da 35 mg / dL ƙara zuwa hadarin ƙwaƙwalwa.
Matsayi na Cholesterol-Sauke Magunguna
Magunguna amfani da su don rage yawan ƙwayar cholesterol - musamman, ma'anar kwayoyin da ake kira statins - an nuna su ƙananan haɗarin samun ciwon bugun jini kuma zai iya rage yawan ciwon bugun jini, idan wani ya faru. Ta rage matakan LDL, statins da sauran ƙwayoyin cholesterol-lowering da kwayoyi sun taimaka wajen hana kwaskwarima, kuma, bi da bi, bugun jini da cututtukan zuciya.
A gaskiya ma, an nuna cewa statins ya rage yawan haɗari da cutar a cikin marasa lafiya da matakan cholesterol na al'ada.
Statins kuma sun taimaka wajen tabbatar da adadin takaddun shaida . Statins na taimakawa wajen sanya alamun marasa lafiya da kuma fibrous, yana sa su zama mafi tsayayya ga rushe. Lokacin da raguwa na guntu, ragowar gwal na kyauta kuma ana ɗauke su a cikin jini, inda zasu iya zama a cikin arteries wanda ke samar da oxygen zuwa kwakwalwa. Bugu da ƙari, ƙwaƙwalwar da aka ruptured zai iya jawo jini zuwa jini, wanda hakan ya kara haɓakar ƙwayar jini. Statins, duk da haka, rage ƙonawa da kuma taimakawa hana rigar daga forming.
Binciken bincike mai zurfi ya kulla dangantaka tsakanin yin amfani da statins da rage rage hadarin bugun jini. Ɗaya daga cikin zane-zane (binciken da ya sake mahimmanci sakamakon binciken da yawa) ya gano cewa amfani da stinine ya rage hadarin bugun jini da kashi 21 cikin dari kuma kowane kashi 10 cikin dari na matakan LDL ya haifar da raguwar kashi 15.6 cikin hadarin bugun jini.
Nazarin ilmin lissafi na musamman sun nuna mahimman sakamako. Yawancin bincike sun gano cewa yayin da statins ke ba da babbar raguwa ga hadarin bugun jini, mafi yawan amfanin da aka gani a cikin waɗanda basu da kisa ba. Kodayake statins suna amfana ga waɗanda suka riga sun kasance akalla guda daya ko bugun jini, tasirin yana da raunana.
Sauran ƙwayoyi na rage yawan ƙwayoyin cholesterol ba su dace da rikodin statins ba. Duk da haka, wasu ƙananan binciken sun nuna alamun kare, musamman ta hanyar taimakawa wajen bunkasa matakin HDL cholesterol. Ɗaya daga cikin binciken Lopid (gemfibrozil), alal misali, ya nuna cewa amfani da Lopid ya rage hadarin fashewa ta kashi 31 cikin dari - tare da mafi girma da aka samu a marasa lafiya da ƙananan matakin farko na HDL.
Cholesterol Guidelines for Rage Rashin Ƙari
Sharuɗɗa na yau da kullum suna samar da burin maganin cholesterol kamar yadda za a rage cututtuka da kuma hadarin cututtukan zuciya. Wadannan jagororin sun bayar da shawarar cewa mutane ba tare da cututtukan zuciya ba wadanda ba su shan taba ba kuma basu da wata cututtukan zuciya (irin su ciwon sukari, hawan jini, kiba, tarihin iyali na cututtukan zuciya) ya kamata kula da matakin cholesterol kasa da 240 MG / dL, tare da LDL žasa 160 MG / dL da HDL sama da 40 MG / dL.
Duk da haka, mutanen da ke dauke da cututtukan ƙwayoyin cuta na zuciya sunyi shawara don neman mahimman ƙwayar cholesterol don kare lafiyar cututtukan zuciya da bugun jini. Wadannan mutane zasu kula da matakin ƙwayar cholesterol da ke ƙasa 200 mg / dL, tare da LDL a ƙasa da 100 MG / dL, da kuma HDL sama da 60 MG / dL.
> Sources:
> Navi BB, Segal AZ. "Matsayin cholesterol da statins a bugun jini." Curr Cardiol Rep. 2009 Janairu 11 (1): 4-11.
> Tanaka T, Okamura T > .. > "Tsarin cholesterol na jini da hadarin bugun jini a cikin ƙungiyoyi masu zaman kansu ko nazarin gwaninta: nazari na 'yan jaridar Japan a cikin shekaru 20 da suka wuce." Keio J Med. 2012; 61 (3): 79-88.
> 2013 ACC / Dokokin Shari'ar Hanyoyi akan Yanayin Zubar da Cutar Kwayar Zubar da Lafi don Rage Ciwon Halitta na Ingancin Tsari na Atherosclerotic a Manya. Yanayi. 2014; 129: S1-S45 An wallafa shi a layi kafin a buga ranar 12 ga watan Nuwamba, 2013, danna: 10.1161 / 01.cir.0000437738.63853.7a