An bayar da shawarar maganin jiyya bisa la'akari da lissafin lamarin da aka lissafa
Magungunan magunguna sun kasance daga cikin magungunan likita a Amurka tare da tallace-tallace na shekara-shekara na dala biliyan 18, kamar yadda bincike daga Ma'aikatar Medicine ta Arewa maso yammacin Feinberg ta Birnin Chicago ta yi.
An san kwayoyi masu magunguna don rage yawan kuskuren ciwon ciwon zuciya ko bugun jini ta hanyar rage yawan "cholesterol" cikin jini.
Amma ba a ba su takaddun da aka samo asali ne kawai akan sakamakon gwajin jini ba. A yau, ana amfani da kwayoyi masu amfani da kwayoyi lokacin da mutum ya lissafi, haɗari daya cikin 10 na ciwon zuciya ko bugun jini a cikin shekaru 10 masu zuwa.
Jerin Tattalin Arbalar Cutar
Gidajen Abincin da Drug Administration na Amurka guda daya an yarda da su, ciki harda kwayoyi guda hudu masu haɗuwa. Hanyoyi bakwai na likitanci sune:
- Lipitor (atorvastatin)
- Lescol (fluvastatin)
- Mevacor (lovastatin)
- Livalo (pitavastatin)
- Pravachol (pravastatin)
- Zocor (simvastatin)
- Crestor (rosuvastatin)
Hakanan ana samun samfurori masu mahimmanci.
Amfanin Drugs
Magungunan ƙananan ƙananan ƙwayoyin ƙwayar ƙwayar cholesterol ta hanyar hana hanta enzyme, wanda aka sani da HMG Co-A reductase, wanda shine maɓallin ƙwayar cholesterol. Yin amfani da wadannan kwayoyi yana da dangantaka da raguwa mai mahimmanci a cikin "mummunan" LDL cholesterol, rageccen ragewa a cikin triglycerides , da karamin ƙãra a " cholesterol " mai kyau.
Wadannan sakamako suna fassara zuwa ƙarin ƙwayoyin cutar na zuciya, ciki har da:
- Ragewa a cikin ginin murya a kan ganuwar arteries
- Yin gyare-gyare na plaques don kada su karya da kuma haifar da katsewa a cikin zuciya ko kwakwalwa
- Rage ƙananan ƙumburi kamar yadda aka auna ta hanyar gwajin C-reactive protein (CRP)
- Rage raguwa da jini a kan shafin yanar gizo
Wadannan cututtuka na iya taimakawa wajen rage yawan jini, musamman ma mutanen da ke ɗauke da cutar karfin jini wanda basu rigaya akan maganin jini ba.
Hanyoyin Farko na Dokoki
Duk da yake kwayoyin magunguna sun ba da amfani mai mahimmanci ga mutanen dake fama da cututtukan zuciya na zuciya, akwai alamun da ke hade da amfani da su. Yawancin suna da sauƙi a matsakaici a cikin matsanancin hali kuma yawanci warwarewa sau ɗaya idan jikin ya daidaita zuwa magani. Mafi yawan sun hada da:
- Jiɗa
- Gas
- Upset ciki
- Ciwon kai
- Dizziness
- Wulo
- Rash
- Tatsauna barci
- Rage maida hankali
- Muscle aches
Statins kuma na iya haifar da tayi a cikin hanta enzymes a cikin ɗaya daga cikin masu amfani 100. A mafi yawancin lokuta, wannan haɓaka ba'a haɗuwa da lalacewar hanta mai haɗari ko mai haɗari, amma kulawa ya kamata a dauki idan an umurci statins ga mutanen dake fama da ciwon hanta.
Statins ma sun kara yawan haɗarin ciwon sukari irin na II na wasu, mafi mahimmanci matan mata .
Wanda Ya Kamata kuma Ya Kamata Bai Dauki Statins ba
An yi rikice-rikice a cikin shekaru masu zuwa game da ko koyayyun dokoki sun zama dole ko daidai da amfani a duk kungiyoyi. Wannan ya sa wasu sun sabawa ma'anar cewa statins basu da amfani, kuma mafi muni, na iya zama cutarwa.
Wannan ba gaskiya bane.
A shekara ta 2016, Gwamnatin Amurka ta Amurka ta ba da jagorancin sharuɗɗa ne kawai don nuna cewa shaidar "ba ta da" don bayar da shawarar farawa statins a cikin mutane 76 da tsufa wadanda ba su da tarihin ciwon zuciya ko bugun jini.
Sanarwar ba ta tsautawa ba ne a cikin wannan rukuni ko wata shawara da ya kamata mutane su daina shan magungunan su idan sun juya 76. Maimakon haka, yana nuna cewa amfanin zai iya zama karami kuma cewa hukuncin shari'a yana bukatar a yi a kan kararrakin -addas.
Ƙarin USPSTF ya ba da shawarwari game da amfani da statins a cikin wadannan rukunin hadarin:
- Yin magani tare da kashi-kashi zuwa kashi-kashi da aka ba da shawarar ga manya 40 zuwa 75 wadanda basu da ciwon zuciya ko bugun jini amma suna fuskantar haɗari. An tabbatar da ƙaddara akan ko mutum yana da ɗaya ko fiye da abubuwan hadarin ga cututtuka na zuciya da kuma kashi fiye da 10 cikin dari na lissafi hadarin ciwon zuciya ko bugun jini a cikin shekaru 10 masu zuwa.
- Haka kuma za'a iya fara magani, tare da hukunci na asibiti, a cikin tsofaffi na wannan rukuni wanda ke da ƙwayar cuta guda ɗaya ko fiye da jini da kuma hadarin lissafi tsakanin kashi 7.5 cikin dari da kashi 10.
> Sources:
> Taylor, F .; Huffman, M .; da kuma Ebrahim, S. "Tsarin Farko na Farko na Rigakafin Cututtukan Lafiya." JAMA. 2013; 310 (22): 2451-2. DOI: 10.1001 / jama.2013.281348.
> Ƙungiyar Ayyukan Tsaro ta Amurka. "Yin amfani da gaggawa don maganin cututtuka na farko na cutar cututtukan zuciya a cikin manya - Dokar Bayar da Shawarwarin Bayar da Taimakon Dokar Dokar Ta'addanci ta Amurka." JAMA. Nuwamba 16, 2016; 316 (19): 1997-2007. DOI: 10.1001 / jama.2016.15450.