Nazarin Binciki Hanya Mai Ma'ana tsakanin Statins da Kumburi
Nazarin sun gano sakamako masu amfani na statins , ciki har da dangantaka tsakanin statins da kumburi .
Mene ne kumburi?
Kumburi wani ɓangare ne na al'amuran al'ada don maganin rauni ko kamuwa da cuta. Lokacin da ka samu raunin rauni (abrasion ko yanke), yankin da ke kusa da shi ya yi rawar jiki kuma ya kara dan kadan. Wadannan alamu ne na kumburi, alamun jikin da ke tattare akan lalacewa.
Yana da wani ɓangare na tsari na warkaswa. Amma ba koyaushe ba ne taimako.
Kumburi yana faruwa ne lokacin da tsarin na rigakafi ya aika a cikin jikin jini na musamman a wani wuri mai lalacewa. Wadannan kwayoyin sun taimaka wajen magance duk wani kamuwa da cuta da kuma tsabtace jikin da aka bari a baya. Haka tsari wanda yake faruwa tare da yanke, kurkusa ko sprain kuma ya faru tare da raunuka ga tsoka tsoka ko arteries.
Matsayin LDL Cholesterol a Kumburi
Hakazalika, jiki yana aiki da kwayar cuta ta damuwar dakaru zuwa wurare masu zafi masu zafi - watau, ƙwayoyin da ƙananan cholesterol ( LDL ) suka yi a cikin ganuwar maganin. Abin takaici, yayin da macrophages ke ɗaukar waɗannan nau'o'in, za su iya zama tare da cholesterol kuma su ƙara ƙara zuwa babban taro (da kuma rikici) na alamar. Ko da yake ana nufi don magance nau'in plaque, mai mayar da martani yana mayar da takarda ba tare da barci ba kuma mafi kusantar rushewa, kuma wannan zai haifar da ciwon zuciya ko bugun jini.
Bugu da ƙari, ƙonewa a cikin zuciya da jini yana haifar da ganuwar jini don ya zama "m" kuma yana iya jawo hankalin ƙarin jinin jini da cholesterol, wanda ke nuna alamar, ko tara a kan bayanan da aka riga ya kasance. Daga ƙarshe, wannan tsari zai iya toshe jini da oxygen.
Idan ciwon da ya shafa ya ba da zuciya ko kwakwalwa, kuma sakamakon, zai iya zama ciwon zuciya ko bugun jini .
C-Reactive Protein a Kumburi
Lokacin da kumburi ya kasance a ko'ina cikin jiki, ana fitar da sunadarin sunadaran cikin jini wanda za'a iya aunawa ta hanyar gwajin jini. Wasu gwaje-gwaje, irin su rashawa mai ƙaurin rashawa (ESR, ko "ƙananan rasha") su ne ma'auni na ƙima. Kwayar C-reactive (CRP) wani ƙari ne na kumburi ko kamuwa da cuta cikin jiki. CRP matakan da ke sama da 10 MG / L sune alamar cewa ƙonewa yana kasancewa a cikin jiki. Duk da haka, a lokacin da aka ɗauke girman CRP, tsakanin 1 MG / L zuwa 3 MG / L, an haɗa shi da matsaloli tare da tsarin zuciya, wato, zuciya da jini.
Duk da yake matakan CRP masu girma sun kasance wani ɓangare na irin halin da jikin ke ciki na matsala, suna da mummunar labarai. Suna iya hango hadarin zuciya a cikin mutanen da ba su taba samun daya ba. A game da marasa lafiya wadanda ke fama da wasu hanyoyi na zuciya - ciki har da angioplasty , matsayi na stent, da kewayar murfin jini - da wadanda ke da ciwon zuciya na zuciya - halayen angina ko angina marasa ƙarfi - wadannan halayen CRP masu girma sun haɗa su an kara haɗari ga ƙwayar zuciya ko bugun jini kuma yafi mutuwa.
A gefe guda, hana ƙinƙarawa yana taimaka wa mutane da ke fuskantar hadarin cututtukan zuciya. Muhimmancin cututtukan zuciya na zuciya sun haɗa da cutar hawan jini , da ciwon sukari , hawan cholesterol mai tsanani, shan taba ko tarihin iyali na cututtukan zuciya.
Menene Statins ke yi a Kumburi da ƙaddamar matakan CRP?
Statins wani nau'i ne mai mahimmanci na magunguna wanda ke rage matakan cholesterol marasa kyau. Statins zai taimakawa cututtukan zuciya, cututtuka da sauran cututtukan da ke da alaka da mummunan cholesterol (LDL) cikin jini. Har ila yau, suna haɓaka jini sosai na kyawawan cholesterol ( HDL ). Statins aiki ta hanyar kulle wani enzyme da ake kira HMG-CoA reductase da cewa yana da muhimmanci ga yin mummunarrol mummunan daga cikakken fats a cikin abinci.
Bugu da ƙari ga rage ƙananan ƙwayoyin cholesterol, statins kuma taimakawa wajen sauko da matakan jini na CRP. Kodayake tasirin maganin cholesterol ya fahimci sosai, ba a fahimci hanyoyin da aka rage rage CRP da kumburi ba. Masana kimiyya sunyi imanin cewa statins sun lalata sunadarai kuma sunadarai kwayoyin da aka saki a matsayin wani ɓangare na tsari na al'ada ta jiki. Rage waɗannan matakan gina jiki yadda ya kamata ya hana kumburi daga faruwa.
Har ila yau, yana nuna cewa yin amfani da statins amfani da dogon lokaci yana haifar da ƙonewa a cikin zuciya da ƙananan matsaloli. Nazarin magungunan marasa lafiya da ke jurewa da hanzari suna nuna cewa wadanda ke daukar kwayoyin kafin suyi hanya suna da ƙananan matakan CRP daga bisani kuma basu iya samun ciwon zuciya ko mutu a cikin shekara bayan hanya.
Nazarin marasa lafiya wadanda ke fama da ciwon shawo kan ƙwayoyin cuta sun gano cewa a cikin gajeren lokaci har zuwa shekara 1 bayan fashewar, marasa lafiya da ke ɗauke da kwayoyin suna da matakan CRP da kuma ingantaccen sakamakon. Wadannan amfani sun haɗa da rashin lalacewar neurologic, kamar maganganu da matsalolin motsi. Har ila yau, akwai mummunar mutuwa a cikin shekara bayan fashewar. Bugu da ƙari, statins rage cututtuka na ƙwayar cuta a cikin mutanen da suka kamu da ciwon zuciya, irin su ciwon zuciya.
Kamar yadda CRP a cikin jini zai iya hango tunanin matsaloli na zuciya, rage yawan matakin CRP na rage rashin lafiyar zuciya da ciwon zuciya ko wasu abubuwan zuciya, ciki har da bugun jini. Kodayake ainihin ingancin har yanzu ba shi da tabbacin, masana kimiyya sun kafa wata hanyar haɗin kai tsakanin statins da rage matakan CRP. Bugu da ƙari, nazarin ya nuna cewa mafi kyawun amfani daga bin ka'idodin su ne wadanda ke farawa tare da manyan CRP; Wadannan amfanin sun fi karfin da za'a iya lissafta su ta tasiri akan tasirin cholesterol kadai.
Yana da muhimmanci mu tuna cewa ragewan matakin CRP da statins bai isa ba don kansa don hana cutar kwakwalwa. Kodayake ƙananan matakan CRP suna da amfani, kowane nau'in haɗari na zuciya-jijiyo - irin su ciwon sukari, hawan jini , shan taba, kiba da / ko high cholesterol - yana taimakawa cututtukan zuciya da kuma haifar da hadarin samun ciwon zuciya ko bugun jini. Hanya mafi kyau don kauce wa waɗannan abubuwa shine motsa jiki, biye da lafiya, mai rageccen mai da kuma biyan magunguna kamar yadda shawararka ta hanyar likita naka don taimakawa ƙananan haɗarinka kamar yadda ya yiwu.
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