Ta yaya Likitocin Ma'aikata na Lymphoma zasu taimakawa wajen bincikar Lymphoma a matakin Ƙungiyar Molecular?
Mene ne alamomin magunguna na lymphoma, ko alamar CD? Me ya sa suke da muhimmancin gaske kuma ta yaya suke taka muhimmiyar rawa wajen maganin lymphomas?
Muhimmancin CD na Likitoci na CD
Tabbatar da alamar CD a kan lymphomas yana da mahimmanci a zaɓar mafi kyau jiyya ga waɗannan cututtuka, amma ba a koyaushe akwai samuwa ba. Bari mu dubi tarihin don fahimtar muhimmancin waɗannan gwaje-gwajen a cikin ƙayyade mafi kyau ga lafiyar ku.
Dalilin da ya sa masu alama na Lymphoma suna da muhimmanci
Gwada tunanin wani nau'i na kwayar halitta wanda ke samar da kusan cibiyoyin ciwon daji kusan talatin - duk suna da suna ɗaya. Yawancin lymphomas daban-daban na iya kasancewa a cikin ƙananan lymph, a matsayin kwakwalwa a cikin kwakwalwarka, a matsayin cuta na ciki, ko kamar yadda jikunan da ke cikin fata. Ba kawai batun batun ba - wani lymphoma da aka samu a cikin kowane ɗayan waɗannan wurare zai iya kasancewa ɗaya daga cikin iri daban-daban. Kuma zabar mafi kyawun magani ya dogara da sanin irin takamaiman.
Kayan ƙwaƙwalwa ba shi da isa don tantancewa Lymphomas
Ko da wasu shekarun da suka gabata, abin da masanin ilimin lissafi ya gani a karkashin na'urar microscope tare da zane mai sauki shine duk abinda muke da shi don gano irin lymphoma. Kuma akwai wasu 'yan nau'ikan lymphoma wanda za'a iya bambanta. Duk da haka, sau da yawa ya nuna cewa irin wannan nau'in ƙwayar cuta ya bambanta a cikin mutane daban-daban. A fili, mun rasa wani abu.
Ma'anar yana cikin ƙwayoyin wuta
A matsayin magani da aka motsa daga kwayoyin halitta zuwa kwayoyin, an tsara fasaha don gano wasu kwayoyin da aka samo a jikin sel.
Lokacin da aka yi amfani da wadannan kwayoyin lymphoma, abubuwa sunyi ban mamaki. Ya bayyana cewa lymphomas ba kawai hannunsu ne na daban ba, amma yafi yawa rikitarwa.
Mene ne alamomin CD na Lymphoma?
A saman sassan lymphocytes, kwayoyin da aka canza zuwa lymphomas, sunyi wasu kwayoyin sunadaran.
Wadannan sune ake kira 'bambance bambancen' ko alamar CD . Yayin da lymphocytes na al'ada ke bunkasa daga sababbin kwayoyin zuwa girma kwayoyin, wadannan alamomi sun canza. An gano cewa lymphomas da suka kasance kama da su a karkashin microscope suna da alamomi daban-daban a saman su. Lokacin da wannan ya faru, sun yi kama da cututtuka daban-daban.
Samfurin CD a cikin ganewar asali
Yau, ilimin ilimin lymphoma ba shi cikakke sai dai idan an gano wasu alamomin lymphoma. Don sanya wani lymphoma a cikin ƙungiyar ta dace, an yi amfani da immunohistochemistry don gano wadannan kwayoyin sunadarai a kan kwayoyin halittun biopsy.
Yanzu muna da kwayoyi masu mahimmanci wadanda ke kai wa kwayoyin CD a kan wasu kwayoyin lymphoma. Wadannan magunguna - sunada magunguna guda daya - kai hari kawai kwayoyin da ke da alamar CD.
Misali na musamman zai iya sa wannan ya fi sauƙin fahimta. Tare da lymphomas, zai iya zama da wuya idan ba zai iya yiwuwa ba a bayyana bambancin tsakanin wasu nau'in ciwon daji. Wasu lymphomas sune lymphomas ne na B kuma wasu su ne lymphomas T, amma kuma sel B da kuma kwayoyin T za su iya kama su a karkashin microscope. Ko da yake sun yi kama da juna, cututtukan da suka shafi wadannan kwayoyin halitta na iya nuna bambanci sosai kuma sun amsa daban-daban ga magunguna daban-daban.
CD20 alama ce ko antigen da aka samu akan farfajiyar B amma ba kwayoyin T ba. Yaduwar babban lymphoma cell (BLBCL) mai yawan ciwon daji na B - zai iya kama da ƙwayoyin lymphoma na cellular anaplastic - ciwon daji na T - ƙarƙashin microscope. Wani gwajin immunohistochemistry, duk da haka, zai iya tabbatar da kasancewar CD20 - antigen da aka samo a jikin B don tabbatar da cewa ciwon daji ne DLBCL kuma ba mai amfani da lymphoma ba. Ana iya rarraba kwayar cell lyphoma mai ɗorewa, ta bambanta, ta wurin kasancewar CD30 antigen.
Masana Alamar Lurauta a Tsarin Dama da Tsarin Dama
Ba ya tsaya a can ba. Wasu alamomi na musamman (ɗaya daga cikin su ana kira bcl-2) zai iya sanar da likita yadda lafiyar ku zai ci.
Wasu wasu (kamar CD20) sune ma'anar ko wani magani zai yi aiki. Misalan alamomin CD da aka kera a cikin maganin lymphoma sun hada da Rituxan antibody (rituximab) wanda ke kai hari ga maganin antigen na CD20 a kan wasu kwayoyin lymphoma da wasu kwayoyin cutar sankarar sankarar lymphocytic.
Kamar yadda karin bincike ke shiga cikin waɗannan alamomin, sabon amfani yana zuwa a duk lokacin. Hakika, lymphoma ya shiga wani zamanin kwayoyin.
Sources:
Cibiyar Cancer ta Kasa. Alamar Tumor. Updated 11/04/15. http://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet