Allergy to Beta Lactam Antibiotics
Mene ne rashin lafiya na Penicillin?
Penicillin shine mai sanannun memba na ƙungiyar maganin rigakafi da ake kira beta lactams, wanda ke nufin wani tsari a cikin kayan shafa kayan shafa. Tsarin kuma ana raba shi da nau'in penicillin mai tsaka-tsalle (amoxicillin), cephalosporins, da sauran maganin rigakafi (kamar imipenem). Penicillins da cephalosporins sune maganin rigakafin da ake amfani dashi don magance cututtuka na kowa.
Penicillins da cephalosporins sune mawuyacin haddasa rashin lafiyar miyagun ƙwayoyi . Kimanin kashi 10 cikin 100 na jama'ar Amirka suna bayar da rahoto game da rashin lafiyar su zuwa penicillin ko kwayoyin maganin. Yayin da alhakin sikila yakan fi faruwa a cikin samari, halayen zai iya faruwa a kowane zamani. Mata sun kasance sun fi girma fiye da maza. Kusan 300 mutuwar za a iya dangana ga rashin lafiyar penicillin a kowace shekara a Amurka. Hanyoyin cututtuka na rashin lafiyar maganin penicillin na iya hada da anaphylaxis , amya, fuka -fatar jiki, fuka-fuka na fuka , da kuma rashin lafiyar cututtuka irin su cututtuka, wasu nau'i na anemia, da sauran rashes.
Ta yaya Penicillin Allergy Diagnosed?
Duk da yake mutane da yawa suna nuna cewa suna da ciwo da furotin din din din, fiye da kashi 10 cikin dari na ainihin suna da ƙwayar rashin lafiya ga miyagun ƙwayoyi. Binciken fata shine hanya mafi kyau don bincikar rashin lafiyar penicillin. Duk da haka, an cire samfurin samfurori don azabar penicillin gwajin fata daga kasuwa a shekarar 2004, saboda matsalolin masana'antu.
Wannan cirewa, wanda ake kira Pre-Pen, ya sake samuwa a shekara ta 2009. A madadin haka, akwai RAST (gwajin jini) don penicillin. Abin takaici, sakamakon RAST mara kyau ba zai hana yiwuwar allergy din penicillin ba.
Ta Yaya Zaman Lafiya na Penicillin?
Baya ga yadda ake maganin alamun rashin lafiyar miyagun ƙwayoyi, mahimmin maganin likitanci na penicillin shine kauce wa yin amfani da cutar penicillin da sauran maganin rigakafi .
Cephalosporins na iya haifar da cututtuka a cikin mutane masu fama da ciwon sikila na penicillin. Hanyoyin rashin lafiyar su zuwa cephalosporin a cikin mutanen da ke dauke da ciwon sikila yana da kimanin 5 zuwa 10%, kodayake rates zai iya zama mafi girma ga wasu mutane. Rashin haɗarin rashin tausayi ga cephalosporins na iya zama mai tsanani har ma da barazanar rai; an bayar da shawarar cewa wadanda ke fama da rashin lafiya ga penicillin guje wa citloslosins duka.
Akwai wasu lokuta, duk da haka, lokacin da mutumin da ke da tarihin fariki na penicillin yana buƙatar gaske na penicillin ko cephalosporin. A cikin waɗannan yanayi, mai ciwon daji zai iya yin gwajin fata, kuma idan yayi mummunan, ba wa marasa lafiya wani ƙananan magani a cikin kulawa ta kusa don sanin yawancin - idan wani - zai iya jurewa (wanda aka sani da ƙalubalen gwaji ). mutumin da yake fama da rashin lafiya ga penicillin yana da kamuwa da cuta wanda ke buƙatar magani tare da penicillin, za a iya aiwatar da tsarin lalatawa a asibiti. Wannan yana hada da bada farko da miyagun ƙwayoyi da kuma karuwan ƙwayoyi na tsawon sa'o'i, har sai mutumin zai iya jurewa cikakken magani.
Wadanne Magunguna Masu Mahimmanci Dole ne Mutumin da ke Kula da Aljilanci na Penicillin Kiyaye?
Iyali na maganin cututtuka na penicillin sun haɗa da:
- Penicillin VK
- Penicillin G
- Dicloxacillin
- Oxacillin
- Nafcillin
- Harshen
- Aminiya
- Augmentin (amoxicillin / clavulanate)
- Unasyn (ampicillin / sulbactam)
- Zosyn (pipercillin / tazobactam)
Iyalin cephalosporins sun haɗa da:
- Keflex (cephalexin)
- Ancef (cefazolin)
- Ceftin (cefuroxime)
- Cefzil (cefprozil)
- Omnicef (Cefdinir)
- Vantin (cefpodoxime)
- Da dama wasu maganin rigakafi da suka fara da "cef-" ko "ceph-"
Tsinkaya zai iya haifar da cututtuka a cikin mutanen da ke fama da ciwon sikila kuma ya kamata a kauce masa.
Kuna son ci gaba da koya? Mutanen da ke da alurar furotin din suna fuskantar haɗari mafi girma na bunkasa rashin lafiyar maganin maganin maganin rigakafi. Koyi game da rashin lafiyar sulfa .
Sources:
Yi amfani da sigogi don maganin cututtuka na Drug. Ann Allergy 1999; 83: S665-S700.
Macy E. Drug Allergies: Abin da za ku yi tsammani, abin da za ku yi. J Respir Dis. 2006; 27: 463-471.
Mellon MH, Schatz M, Patterson R. Drug Allergy. A cikin: GJ Lawlor, Fischer TJ, Adelman DC, eds. Manual na Allergy da Immunology. 3rd ed. Boston: Ƙananan, Brown da Co, 1995: 262-289.
Romano A, Gueant-Rodriguez RM, Viola M, Pettinato R, Gueant JL. Tsunin-kwance-kwakwalwa da Toleratbility na Cephalosporins a cikin marasa lafiya tare da nan da nan Hypersensitivity zuwa Pencillins. Ann Intern Med. 2004; 141: 16-22.