MTHFR Gene da TRPV1 Gene da Taimaka wa Migraines
Idan ka sha wahala daga lalacewa na migraines, akwai kyakkyawar damar da 'yar'uwarki, dan uwanka, ko mahaifiyarka ta yi. Wannan shi ne saboda jinsinku na sa ku kara ko ƙananan mai saukin kamuwa da ƙauraran ƙaura.
Bari mu binciki kwayoyin halittar migraines kuma abin da wannan ke nufi a gare ku da iyalinku.
Haɗin tsakanin Tsakanin Halitta da Muhalli a cikin ciwon kai
Mafi yawan ciwon kai shine sakamakon yawan kwayoyin halitta da abubuwan da ke cikin muhalli suna hulɗa a cikin yanar gizo mai rikitarwa.
Yayinda yawancin ku ke aiki ba tare da bata lokaci ba akan sarrafa abubuwan da ke halayen muhalli ta hanyar haifar da kaucewa da gyare-gyaren hali, to ba za ku iya canza jinsin da aka haife ku ba. Duk da haka, ta hanyar nazarin kwayoyin halitta da suka shafi asalin ƙaura, masana kimiyya zasu iya ƙirƙirar sababbin kwayoyi da suka dace da wasu kwayoyin halitta, a cikin bege na maganin, idan ba ta sauke nauyin ciwon da muke ciki ba.
Wadanne Dabbobi ne ke Cikin Migraines?
Akwai muhimmiyar rawar gādo a ci gaba da ƙaura da sauran ciwon kai . An nuna wannan ta hanyoyi masu yawa na iyali da na biyu. Amma menene hakikanin ainihin gine-ginen da aka saukar? Da ke ƙasa akwai misali na kwayoyin halitta biyu da ake tsammani zasu taka muhimmiyar rawa wajen samar da migraines.
Kwayar daya ana kiransa jigidar MTHFR , wadda take tsaye ga dogon lokaci, methylenetetrahydrofolate reductase. Wannan nau'in yana cikin hanyar homocysteine. Homocysteine amino acid ne a cikin jini cewa lokacin da aka hawanta, zai iya haifar da kumburi na jini, da kuma kwarewa daga wasu kwayoyin jikinsu wanda zasu iya shiga cikin ciwon kai.
Wasu maye gurbin a cikin wannan jinsin an hade su tare da magunguna da kuma ciwon kai na cluster .
Ɗaya daga cikin binciken da aka yi a Pharmacogenetics da Genomics ya gano cewa a cikin mata da migraine tare da aura , karin kayan bitamin ya sauke da matakan homocysteine, matsanancin ƙwayar ƙwayar cuta, da kuma nakasassu ta ƙaura, idan aka kwatanta da matan da suka dauki wuri.
Ana amfani da karin bitamin tare da bitamin B6, B9 (folic acid), da kuma B12, wanda aka samo su zuwa matakan homocysteine a cikin jini.
Bugu da ƙari, a lokacin da aka bincika ƙungiyar bitamin a hankali, an gano cewa marasa lafiya tare da wani alamar gwanin MTHFR sun sami raguwa mafi girma a matakan homocysteine, da ƙananan ƙwayar ƙwayar cuta da kuma nakasa, fiye da wadanda ke da nau'i daban-daban . Mai gani shine wani nau'i nau'i na jinsin da ke da wani wuri a kan wani ƙananan chromosome. Wannan binciken ya nuna cewa wasu jinsunan jinsin halitta zasu iya tasiri yadda yadda 'yan gudun hijirar ke amsawa ta hanyar kariyar bitamin.
TRPV1 (Maɗaukakiyar Maɗaukaki Mai Mahimmanci Vanilloid Type 1) an ba da shawarar yin aiki mai mahimmanci a cikin haɓakawa na migraine - wata kalma wadda take nufin tsarin da ba a juyayi ko mai juyayi a cikin marasa lafiya tare da migraines.
Wannan jinsin yana taka rawar a cikin hydraralgeia da kuma allodynia , yanayin biyu wanda zai iya faruwa a lokacin harin kaiwa. Hyperalgesia yana nufin ƙara karuwa ga mai daɗaɗɗa mai raɗaɗi. Allodynia tana nufin mayar da martani ga wani abu mai mahimmanci marar lahani, kamar jin tausayi tare da sauƙi mai sauki a lokacin harin kaiwa.
A cikin 'yan shekarun da suka wuce, an yi amfani da kwayoyi masu amfani da tashoshin TRP a matsayin magungunan ƙwayar ƙaura.
Misali na miyagun ƙwayoyi wanda ke fuskantar tasirin TRPV1 shi ne sumatriptan , wata magungunan ƙaura na kowa.
Menene Wannan Ma'anar Na?
Babban hoto a nan shi ne cewa migraines suna da asali mai karfi. Ta hanyar ƙarin koyo game da wasu kwayoyin da suka sa mutum ya zama na migraines, masana kimiyya zasu iya amfani da kwayoyi zuwa wadannan kwayoyin.
Har ila yau, fahimtar tsarin jinsin rayuwa na iya taimakawa wasu daga cikin nauyin da mutane ke fuskanta, yayin da suke kokarin gudanar da hare-haren su na migraine. Ka yi la'akari da tantaunawar tarihin iyalinka tare da mai bada sabis na kiwon lafiya, saboda wannan zai iya ba da basira game da ƙaurawar ka da kuma tasiri na gaba.
Sources:
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