Ƙarƙashin Sprinkles da sauran Valproate Forms
Valproate shi ne miyagun ƙwayoyi da aka lissafa a matsayin magungunan antionvulsant kuma ta haka ne aka ba da umurni da yawa don sarrafa kaya. An kuma umarce shi a wasu lokuta don hana ciwon kai na ciwon kai da kuma rage yawan farfadowa na manya a cikin ɓarna. Wasu likitocin sun kuma rubuta shi don magance matsalolin ƙalubalen da ke cikin cutar Alzheimer da sauran nau'in lalata .
Yin amfani da valproate a wannan hanyar ana dauke da lakabin-lakafta tun da Cibiyar Abinci da Harkokin Kiyaye ta Amurka (FDA) ba ta yarda da ita ba don wannan amfani.
"Valproate kayayyakin sun hada da valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, da Depakote ER), valproic acid (Depakene da Stavzor), da kuma generics," a cewar FDA.
Daban-daban daban na Valproate
Valproate ya zo cikin nau'o'i daban-daban, ciki har da Allunan, ɗakunan da aka kwashe-kwashe masu yawa, capsules tare da furofesa sprinkling (wadannan capsules za a iya haɗiye duk ko bude kuma abin da ke ciki yafa masa abinci mai laushi ga wadanda ke fama da wahalar haɗiye) da injections / IVs ga wadanda basu iya dauki magungunan magunguna.
Me ya Sa An Yi Amfani da Shafin Farko don Yin Halayyar Ƙaƙwalwa a Cikin Dama?
Ɗaya daga cikin matsalolin da cutar Alzheimer ke ciki shine cewa mutane da dabi'u zasu iya canzawa sakamakon cutar. Wasu daga cikin halayyar kalubalanci a cikin rikici za su iya haɗa da tashin hankali , rashin natsuwa, haɗuwa , maganganun magana , tsayayya da kulawa, ɓoyewa da tunani marar kyau .
Yana da wuya a san yadda za a amsa wadannan nau'ukan da motsin zuciyar.
Ƙungiyar kiwon lafiya ta yi kokarin gwada kwayoyi daban-daban don kokarin rage waɗannan halayyar, ciki har da magungunan antipsychotic (wanda zai iya haifar da mummunar tasiri kuma an kafa shi sosai a cikin masana'antar gidaje masu noma), benzodiazepines (wanda ya zo tare da sakamako mai tasiri da tasiri mai tasiri) da kuma antidepressants (wanda basu da tasiri ko dace).
Labaran ƙasa shine cewa akwai gaba ɗaya ba magani mai mahimmanci don bi da halayen halayyar hali a cikin lalata .
Saboda haka, valproate ya tashi a matsayin mai takaici a cikin ƙoƙarin ƙoƙarin magance matsalolin tashin hankali. Bugu da ƙari, cewa bege yana kasancewa magani mai kyau, valproate yana da amfani da kasancewa magani wanda ya fara tafiya kadan a karkashin radar bisa ka'idodin kulawa da gidaje-wanda aka mayar da hankali ga ragewa da kuma kawar da magungunan antipsychotic a cikin dementia amma ba kamar yadda mayar da hankali a kan valproate.
Ya kamata a yi amfani da Valproate don magance matsalolin ƙalubalen da ke ciki?
Bisa ga nazarin binciken bincike da yawa, amsar ita ce: A'a.
Me yasa ba?
Yana da sau da yawa m. Kodayake akwai maganganu masu mahimmanci na al'amuran, ƙididdigar nazarin binciken da yawa sun tabbatar da cewa valproate bai kasance mai taimako fiye da kwayar cutar ba (inji kwayar cutar) a rage yawan halayyar da ake fuskanta na lalata.
Bisa ga wani binciken da aka wallafa a JAMA Psychiatry , basproate kuma ya kasa rage jinkirin ci gaba da ciwon hankali, rashin amfana da amfani da bai fito da amfani ba.
Hanyoyin Gaba
Binciken da yawa ya gano cewa mahalarta wadanda suka karbi baftisma sun kasance cikin haɗari ga illa masu illa daga magani.
Wadannan cututtuka sun hada da thrombocytopenia (raguwar jini), ƙaruwa mai tsanani, damuwa da tashin hankali, tashin hankali, tashin hankali da barci, tashin zuciya, zubar da jini, da kuma zawo.
Alternatives zuwa Valproate
Maimakon kai ga kwalban magani don canza yanayin halayya a cikin rikice-rikice, tsarin farko shine ya zama magungunan miyagun ƙwayoyi . Yi la'akari da abubuwan da zasu iya haifar da waɗannan dabi'u irin su yanayi , ciwo na jiki , rashin jin daɗi ko raguwa kuma yayi ƙoƙari don magancewa da daidaita waɗannan matsaloli.
Yi amfani da hanyoyin da za a iya ba da damar dan lokaci don kwantar da shi kadai sannan kuma dawo daga baya don kammala aikin da kake ƙoƙarin cim ma.
A ƙarshe, gane cewa damun kulawa da ƙonawa zai iya haifar da halayen mutumin da ke da lalata. Kula da kanka don alamun kulawa da kulawa da kuma amfani da iyali, abokai da albarkatu na gari don tallafa maka a cikin aikin kula da ku.
Kalma daga
Daidai ne da ya dace don neman magungunan da ke taimakawa tare da halayen halayen da sukan ci gaba da rikici. Abin takaici, har yanzu ba mu sami mafita mai kyau ba kuma mai amfani da magani don wannan dalili.
Saboda wannan, tabbatar da neman tallafi a matsayin mai kulawa tun lokacin da alamomi da halayyar kwakwalwa na damuwa na iya zama damuwa don rikewa. Wannan goyon baya zai taimake ka ka ji ƙanƙantar da kai kuma ka ba da damar taimakawa wajen raba wasu hanyoyin da suka taimaka maka.
> Sources:
> ClinicalTrials.gov. Valproate a Dementia (VALID). Yuli 6, 2010.
> Ƙungiyar Cochrane na Kamfanin Gudanarwa. 2009 Yuli 8; (3). Shirye-shiryen Sharuɗɗa don Tabbatarwa a Dattiya.
> Depakote. Takaddun tsari.
> JAMA Dama. Na'urar Divalproex Sodium zuwa Cibiyar Tattaunawa da Ci Gaban Ciwon Alzheimer.
> Mental Health Clinician. 2012; 1 (11): 14. Bayar da Valproate a cikin Al'ummar Al'umma da Ƙaddamarwa: Bayani akan Ƙasantawa da Rage Ƙasa.
> Cibiyar Abinci da Drug. Bayanin Sabis.
> Williams, Dukkansu sunyi aiki game da Shaida: Valproate for Agitation in Dementia.
> Yeh, Y. da Ouyang, W. (2012). Shirye-shiryen yanayi don lura da alamun cututtukan hali da na kwakwalwa na lalata: Rahoton sabuntawa. Jaridar Kaohsiung na Kimiyyar Kimiyya , 28 (4), pp.185-193.