Statins ba da kyauta kaɗan ga masu lafiya
Statins ne mafi yawancin wajabtaccen cholesterol-ragewan magunguna da ke shafar dukkan fannoni na bayanan cholesterol.
Amfanin statins sun hada da:
- Ƙasawa LDL da matakan triglyceride
- Girman matakai na HDL
- Rage hadarin cututtukan zuciya
- Tsayar da hare-haren zuciya da ciwon zuciya a cikin marasa lafiya da suka kamu da cututtukan zuciya
Koda a cikin amfanar da za a iya ɗauka, wasu marasa lafiya suna jin kunya daga gare su saboda suna ganin sakamakon da zai haifar da cutar ta haifar da mummunan cutar.
Shin marasa lafiya sun dace su guje wa statins saboda sakamakon lalacewa?
Ƙananan Amfani ga Masu Samun lafiya
Statins na iya amfana da marasa lafiya da tarihin cututtukan zuciya, amma yanayin da ake tsara ka'idoji ga masu lafiya don rage haɗari zai iya kawo ƙarshen ƙaddamar da edita na 2015 wanda aka wallafa a mujallar Prescriber. Rahoton ya bayyana cewa, bayan da ya dauki shekaru 5, kashi 0.5 cikin 100 na marasa lafiya sun guje wa ciwon zuciya ko bugun jini. Masu marubuta, likitan likitancin London da kuma likitan likitancin Amurka, suna kira ga cikakken rubutawa na jagororin Amurka da Birtaniya.
Hanyoyin Enzyme na Hawan Nuna Tsarin Dokoki
Dukkan kwayoyin magungunan sunadaran hawan enzymes har zuwa aminotransferase (AST) da alanine aminotransferase (ALT), wanda mai kula da lafiyar ku ke kulawa kafin ku fara aikin likita, bayan watanni uku bayan farawa, kuma a kalla a kowane watanni shida yayin da ake ci gaba da aikin likita.
Wadanda ke dauke da hanta enzymes bazai lura da wani bayyanar cututtuka ba.
Tsare-tsaren tsararru na statins suna inganta hanta enzymes a kimanin kashi 1 cikin dari na marasa lafiya, yawanci a cikin watanni huɗu na farko. Zai yiwu wannan tsayi ya ƙaru a cikin tsofaffi da kuma wadanda ke shan magunguna da zasu iya hulɗa da statins ko kuma tada hanta enzymes.
Wannan tasirin sakamako na statin yana dogara ne da kashi-kashi, wanda ke nufin cewa mafi girman kashi na statins da kake dauka, mafi kusantar zaku sami karuwa a cikin hanta enzymes.
Akwai rahotanni masu raguwa game da rashin ciwon hanta da kuma ciwon daji da ke hade da statins da hawan enzymes hanta. Binciken na yau da kullum ba su iya kafa hanyar haɗakarwa tsakanin amfani da statin da cutar ciwon hanta ba.
Matakan enzyme masu haɗari masu hanta suna komawa al'ada lokacin da ka daina ɗaukar statins.
Mawuyacin Musamman da Rashin Lahani Yayi Ƙari na La'idodi
Myopathies, ko bayyanar cututtuka irin su rauni da ciwo, sune wani sakamako na gaba na statins.
Myopathies yana da tsauri daga mummunan ƙwayar cuta , ko tsokawar baƙin ciki , zuwa yanayin da ke barazanar rai da ake kira rhabdomyolysis. Mafi yawan maganin da ke tattare da amfani da kwayoyin halitta, myalgia , yana faruwa ne kawai game da 1 daga kowace 1,000 marasa lafiya da ke daukar kwayoyin.
Samun damar fuskantar wannan sakamako na statin yana ƙaruwa yayin da kake tsufa, tare da ƙananan asibiti da kuma yayin shan wasu magunguna. Wadannan bayyanar cututtukan zasu bayyana a cikin watanni hudu na farawa tsarin farfadowa.
Rhabdomyolysis, wani mummuna wanda zai iya faruwa tare da yin amfani da statin, yana da mahimmanci da m idan ba'a bi da shi ba. Yana faruwa a cikin mutum guda daga mutane 10,000 da ke ɗauke da statins.
Kwayoyin cututtuka na rhabdomyolysis sun hada da:
- Jin zafi tsoka
- Rashin rauni
- Yawanci ƙara yawan creatinine phosphokinase
Shin Amfanin Amfani da Rashin Ƙari?
Wannan shawara ce da kai da mai kula da lafiyar ku ya kamata ku yi.
Idan kana shan statins don yanayin lafiyar halin yanzu, watakila sakamakon da ke tattare da yin amfani da statin ba su da kyau sosai idan ka kwatanta shi zuwa ga amfanin.
Idan mai kula da lafiyar ku ya ba da shawara cewa abubuwa kamar ma'auni ne, kada ku tabbata cewa kuna da duk bayanan da kuke buƙata, ciki har da sabon binciken, don yin shawara mai kyau.
Sources:
Armitage J. Tsaro na statins a cikin asibitin yi. Lancet . 2007; 6736 (07): 60716-8.
De Denus S, Spinler SA, Miller K, et al. Statins da ciwon hanta: wani zane-bincike. Pharmacotherapy . 2004; 24 (5): 584-591.
Harper CR da Jacobson TA. Hanyoyin da ake amfani da su a ka'idar myopathy: daga myalgia zuwa rhabdomyolysis. Curr Opin Lipidol . 2007; 18 (4): 401-08.
Jacobson TA. Tsare-tsare na kariya: darussa daga sababbin aikace-aikace na miyagun ƙwayoyi don kasuwancin kasuwa. Am J Cardiol . 2006; 97 (8A): 44C-51C.
Spencer B. Daily Mail: Masu amfani da lafiyar Amfani da Statins sun fi dacewa don shawo kan raunin-rafi fiye da lafiyar lafiyar lafiyar '