Binciken da aka yi kwanan nan ya samo ƙananan ƙananan kwayoyin halitta amma ƙari ne ga ƙwayar lymphoma da kuma wasu ciwon daji biyu a marasa lafiya tare da psoriasis. Amma, akwai ƙari ga wannan labarin fiye da saduwa da ido.
Psoriasis
Psoriasis yana daya daga cikin cututtuka na fata na kowa, hade da alamun bayyanar cututtuka irin su ciwo, zafi, ko zub da jini. Yankunan da ke cikin fata suna bayyana a matsayin jan, wuraren da ake kira da ake kira plaques, wanda za'a iya rufe shi da ƙananan siliki.
Daban-daban na psoriasis na iya samun bambancin bayyanuwa da alamu daban-daban na shafi fata.
Psoriasis an dauke shi da yanayin ƙwayar cuta , wanda zai iya samun abubuwan da zai haifar da-kuma ya raba abubuwan cututtuka tare da wasu cututtuka, ciki har da wasu malignancies. Kuma mutane tare da psoriasis sunyi kwangila da wasu cututtukan da ke da alaka da yiwuwar a mafi girma fiye da za a sa ran bisa lambobi daga yawan jama'a, ciki har da:
- Psoriatic arthritis
- Crohn ta cutar
- Wasu malignancies
- Dama
- Cutar marasa ciwo marasa lafiya
- Ciwon maganin ƙwayar cuta da cututtukan zuciya
Lymphoma
Lymphoma shine ciwon daji wanda ke rinjayar lymphocytes, irin nau'in jini wanda yake samuwa a cikin jini kuma yana cikin kasusuwan kasusuwa da ƙwayoyin lymph . Lymphoma na Hodgkin, ko HL, da lymphoma ba Hodgkin , ko NHL, su ne manyan nau'o'in lymphoma.
Saboda lymphocytes sune wani ɓangare na tsarin rigakafin, masu bincike sunyi mamakin dangantakarsu tsakanin cututtuka da cutar lymphoma.
Har zuwa yau, suna ci gaba da kokarin gwada dangantaka tsakanin su biyu.
Psoriasis & Lymphoma: The Link
Cibiyar Cancer na Amurka (ACS) ba a lissafin jerin psoriasis a halin yanzu ba a matsayin lamarin haɗari ga lymphoma. Suna yin, duk da haka, sun haɗa da cututtuka na asibiti a cikin jerin sunayen abubuwan haɗari ga NHL, suna ambaton cututtuka na rheumatoid da tsarin lupus erythematosus kamar misalai.
Ritumatoid arthritis, psoriasis, da kuma cututtukan zuciya na huhu (IBD) duk an nuna cewa an hade da haɗarin lymphoma a cikin wasu, amma ba duka nazarin ba.
Hanyoyin rigakafi mai cututtuka a cikin cututtuka na kwayoyin halitta na iya haifar da ƙwayar lymphocytes da rarraba sau da yawa fiye da al'ada, wanda zai yiwu ya kara yawan ƙwayar lymphoma. Kamar yadda ACS ta nuna, duk da haka, mutanen da ke samun NHL suna da ƙananan ko babu sananne; kuma ko da wani mutum tare da NHL yana da ɗaya ko fiye da halayen haɗari, yana da wuya sosai a san yadda waɗannan dalilai zasu iya taimaka wa lymphoma.
Ƙãra yawan lymphoma da aka ruwaito a cikin yawan karatu na marasa lafiya tare da psoriasis. Kuma hadarin lymphoma tare da jami'o'in halittu, a cikin maƙasudin, ya kasance batun batun muhawara. Masana ilimin halitta sunyi tasiri a cikin maganin cututtuka kamar rheumatoid arthritis da psoriasis. Yayin da aka nuna su zama mai lafiya, suna aiki ta hanyar kawar da tsarin rigakafi-don haka akwai damuwa cewa wannan zai haifar da haɗari ga wasu cututtuka.
Akwai yiwuwar ƙara yawan ciwon cututtuka irin su lymphoma a cikin mutane tare da psoriasis, amma akwai wasu matsalolin da ke karatun irin wannan hanyar:
- Kodayake lymphoma yana da muhimmanci ga lafiyar jama'a, yawanci yana da mahimmanci idan aka kwatanta da psoriasis, wanda ya sa ya zama wuyar samun adadi mai yawa don nazarin.
- Samun psoriasis yana hade da ilimin lissafi tare da dalilai masu yawa, kamar shan taba, kiba, da kuma ultraviolet farfesa da kuma kwayoyi da suke hana tsarin rigakafi. Wadannan dalilai na iya ƙara haɗarin lymphoma da sauran cututtuka, mai zaman kanta na psoriasis kanta.
Kwanan nan, masu bincike sun tantance rikodin daga 198,366 marasa lafiya da psoriasis da 937,716 ba tare da psoriasis ta amfani da bayanai a Birtaniya. Sakamakon ya nuna cewa akwai karami amma "ainihin hakikanin ainihin" ya kara haɗari ga wadanda basu da ciwon daji na fata, lymphoma, da ciwon huhu a cikin mutanen da suke da psoriasis.
Wadannan masu bincike sun gano cewa hadarin ciwon daji ya kasance mafi girma ga marasa lafiya wanda aka lakafta suna da psoriasis mai tsaka-tsaki kamar yadda ya saba da rashin lafiya. Babu wata babbar dangantaka tsakanin psoriasis da ciwon daji na nono, mahaifa, prostate, ko cutar sankarar bargo, duk da haka.
Ko da kwanan nan, likitoci daga Cibiyar Nazarin Labaran Halitta a Wake Forest School of Medicine a Winston Salem, North Carolina sun gudanar da binciken da ya shafi hakan. Sun lura cewa psoriasis yana haɗuwa da wasu yanayi daban-daban na kiwon lafiya ko haɓaka.
Har ila yau, sun ji cewa yawan hadarin daga psoriasis-sau da yawa ya ruwaito likitoci da marasa lafiya kamar yadda haɗarin dangin ke iya zama-mafi mahimmanci. Yayin da hadarin dangi zai iya zama da amfani, masu marubuta sunyi tunanin cewa tunani game da hadari a cikin sharuddan dangi, maimakon kalmomin cikakke, zai sa mutane su yi la'akari da sakamakon psoriasis.
Saboda haka, ƙungiyar bincike ta tsara don lissafin cikakken haɗari ga psoriasis ga cututtuka daban-daban. Halin da ake danganta da psoriasis mafi karfi (tare da haɗarin dangin mafi girma) sune ciwon daji na fata, melanoma, da lymphoma kamar yadda aka gani a nan:
Abun Abun Abun Cutar Abun Neman Psoriasis-Risk Number of Patients
Ciwon daji na fata 7.5 0.64 1,551
Melanoma 6.12 0.05 29,135
Lymphoma 3.61 0.17 5,823
* Don yada labaran lymphoma zuwa psoriasis, likita zai ga likitoci 5,823 tare da psoriasis.
Sources:
Saleem M, Kesty C, Feldman S. Mai mutunci dangane da cikakken hadarin comorbidities a marasa lafiya tare da psoriasis. J Am Acad Dermatol . 2016 Dec 13. Koma: S0190-9622.
Fuxench ZC, Shin DB, Beatty AO, Gelfand JM. Rashin ciwon ciwon daji a cikin marasa lafiya da psoriasis: nazari na ƙungiyar jama'a a cikin Cibiyar Inganta Lafiya (wanda aka buga a kan layi gaba da buga ranar 16 ga Disamba, 2015). JAMA Oncol.
Boehncke WH, Boehncke S. Fiye da fata-zurfi: da yawa girma na psoriatic cuta. Swiss Med Wkly. 2014; 144: w13968.