Yadda ake aiki, Hanyoyin Yanayi, da Ƙari
Gabapentin magani ne wanda aka saba wa fibromyalgia . Ana samuwa a matsayin jigilar jini kuma an sayar da shi a ƙarƙashin alamun sunayen Neurontin, Horizant, da Gralise.
Gabapentin ba FDA da aka yarda don magance wannan yanayin ba, saboda haka an rubuta shi-lakabin. Wannan miyagun ƙwayoyi yana da dangantaka da Lyrica (pregabalin) , wanda aka yarda a matsayin magani na fibromyalgia.
A gaskiya ma, Lyrica wani lokaci ake kira "dan Neurontin."
Ana kirga Gabapentin a matsayin magungunan rigakafi. An yi amfani dasu don maganin cututtuka, neuropathy (ciwo daga jijiyoyi masu lalacewa), rashin ciwon ƙafafun kafa , da kuma walƙiya.
Fibromyalgia ciwo yana kama da neuropathy, amma ko wannan yanayin ya shafi ciwon daji har yanzu ba a fili.
Ta yaya Gudun Kayan aiki yake aiki?
Gabapentin an yi imanin aiki ne ta hanyar sauya sutura da sauran masu amfani da su a cikin kwakwalwarka. Masu watsa layi na aika saƙonni daga ɗayan kwakwalwa zuwa wani.
Glutamate yana da taimako ga wasu abubuwa, kamar koyo sabon bayani. Wannan shi ne saboda yana samun kwakwalwarka ta kwayoyin halitta da tayi aiki.
Kyakkyawan kama da yaro tare da cakulan, ko da yake, idan kuna da yawa da yawa da ke gudana a can, kwakwalwarku zata iya zamawa ta hanyar motsa jiki. Wannan zai iya yin kowane nau'i na abubuwa ba daidai ba.
Glutamate yana da aiki fiye da ɗaya, ko da yake.
Har ila yau, yana taimakawa wajen aika sakonni masu zafi a kwakwalwarka da jijiyoyi. Yawancin abu mai yawa zai iya taka muhimmiyar rawa a cikin hyperalgesia , wanda ke da sauƙi ya juya ƙarar zafi.
Don magance ilimin glutamate, kana da wani sabon neurotransmitter da ake kira gamma-aminobutyric acid (GABA) . Yana kwantar da hankalin ku kuma yana kwantar da kwakwalwarku.
Lokacin da GABA da glutamate sun kasance a ma'auni tare da juna, abubuwa suna ci gaba.
Wasu cututtuka da yanayi na iya katse wannan ma'auni kuma bari glutamate gudu amok. Ana ganin Gabapentin don rage kwakwalwar kwakwalwarka don yaduwa don haka sel zasu iya kwantar da hankali kuma kwakwalwarka zai iya aiki mafi kyau.
Gabapentin ga Fibromyalgia
Bincike ya nuna cewa mutane da fibromyalgia sunyi yawa a wasu sassan kwakwalwarsu, saboda haka an riga an umarce su da su.
Amma yana da tasiri? Binciken bincike ne.
Bincike biyu na shaidu basu yarda ba. An sake saki a 2016 cewa gabapentin yana da tasiri na maganin fibromyalgia, amma wani, wanda aka buga a shekara ta 2017, ya ruwaito kawai shaidar bashi.
Binciken da aka yi a shekara ta 2014 game da fibromyalgia da neuropathy sun gano cewa kimanin kashi 35 na masu halartar nazarin ya ga yadda ciwon ya ragu da kashi 50 cikin 100 yayin da yake kan wannan magani. Yana da muhimmanci a lura da cewa, kashi 21 cikin dari na ganin irin wannan sauƙi a lokacin da take daukar wuri.
A cikin nazarin kwatanta gabapentin tare da pregabalin (magani a Lyrica), ciki har da wanda aka buga a The Journal of the American Medical Association, pregabalin ya bayyana ya yi mafi alhẽri.
Wani sashi na gaba-gaba ya nuna alƙawari a cikin ƙaramin ƙararrakin da aka buga a cikin Pain Practice .
Masu bincike sun ce ya cigaba da ciwo, barci, da kuma rayuwa mai kyau. Wannan shi ne gwaji na farko, duk da haka, don haka dole a yi aiki da yawa kafin mu san tabbas yana da lafiya da kuma tasiri na tsawon lokaci.
Gwanin Gabapentin
Gabapentin yawanci ana farawa a ƙananan ƙananan kuma sai ya karu da hankali. Tabbatar ku bi umarnin likitanku.
Hanyar jigilar jiki tsakanin 900 MG da 1,800 MG yau da kullum, zuwa kashi uku.
Bai kamata ku daina barin gaba gaba ba. Tabbatar yin magana da likitanku game da yadda ake dacewa da ƙuƙwalwa don ƙimar da kake ɗauka.
Gabapentin Side Effects
Kamar duk kwayoyi, gabapentin ya zo tare da hadarin sakamako masu illa.
Wasu suna da haɗari yayin da wasu ba su da kyau.
Idan kana da wasu daga cikin sakamakon da ke ciki a yayin da kake shan gaba, kira likitanka nan da nan:
- rauni mai tsanani na gajiya
- ƙananan ciwon ciki
- zafi ciwo
- sabon ko tsofafin tari tare da zazzaɓi
- wahalar numfashi
- babban tingling ko numbness
- hanzari, sauye-sauye-da-ido ido
- zafi ko wahala tare da urination, ko a'a urination
- zazzabi
- ciwon makogwaro
- kumburi a fuska ko harshe
- ƙona wuta
- rash
Hanyoyin da ba'a haifar da damuwa ba da sauri sun haɗa da:
- gajiya
- dizziness
- ciwon kai
- barci
- riba
Yara masu shan gaba suna iya samun wani nau'i na tasiri. Tuntuɓi likitanku nan da nan don wadannan:
- canje-canje a cikin hali
- ƙwaƙwalwar ajiya
- rashin iyawa
- rashin tausayawa, ƙiyayya, ko zalunci
Gabapentin na iya amsa mummunan kwayoyi. Tabbatar likita da likitan kwarewa sun san duk abin da kake ɗauka.
Shin Gabapentin Dama a gare ku?
Tare da shaidar kasancewa mai rauni da kuma gauraye, gaba ɗaya yana da amfani daya akan Lyrica-yana da jigilar, sabili da haka yana da tsada sosai. Bambancin farashin yana haifar da wasu mutane don gwadawa gaba daya duk da rashin ƙarfi a cikin binciken.
Bugu da ƙari, dukkanmu muna da mahimmanci ga magunguna. Wasu mutane da suka kasa yin amfani da wasu magunguna zasu iya samun taimako daga gaba.
Idan kana sha'awar ƙoƙari na gaba, magana da likitanka game da kwarewa da magungunan miyagun ƙwayoyi da kuma yadda zai dace cikin tsarin kulawar ku.
> Sources:
> Calandre EP, Rico-Villademoros F, Slim M. Apha2delta ligands gabapentin, pregabalin da mirogabalin: wani bita na maganin maganin likita da maganin likita. Binciken gwani na neurotherapeutics. 2016 Nov, 16 (11): 1263-1277.
> Cooper TE, Derry S, Wiffen PJ, Moore RA. Gabapentin ga ciwon fibromyalgia a cikin manya. Cochrane database na dubawa tsarin. 2017 Jan 3; 1: CD012188.
> Moore RA, Wiffen PJ, Derry S, et al. Gabapentin ga ciwon neuropathic na kullum da fibromyalgia a cikin manya. Cochrane database na dubawa tsarin. 2014 Apr 27; (4): CD007938.
> Moore A, Wiffen P, Kalso E. Magungunan rigakafi don ciwon daji da fibromyalgia. JAMA. 2014 Jul; 312 (2): 182-3.
> Arewa JM, Hong KS, Rauck RL. Sakamakon wani nau'i na wallafe-wallafe-rubuce-rubuce a kan ciwo da barci a cikin batutuwa fibromyalgia: binciken da aka yi da alamar kamfani. Hanyar shan wahala. 2016 Jul; 16 (6): 720-9.