Shin maganin ƙwayar ku na ƙwannafi ne yake haifar da ku?
Shin shan magani na ƙwaƙwalwarka zai iya taimaka wa bayyanar IBS ? Masu bincike suna kallon yiwuwar dangantaka tsakanin yin amfani da masu hana kwantar da hankalin proton (PPIs) da ƙananan kwayar cutar ta jiki (SIBO). Tun da yake SIBO ya zama dalili a kan wasu lokuta na IBS , duk wani dangantaka tsakanin mutane uku ya cancanci kallo.
Mene ne PPIs?
PPI su ne magunguna da suke aiki ta hanyar ragewa da mugun ciki na ciki.
An umarce su don magance yanayin kiwon lafiya daban-daban, ciki har da cututtukan gastroesophageal (GERD) da kuma cututtukan fata. Kodayake yawancin PPI na buƙatar takardar sayen magani, akwai wasu da suke kan-da-counter. Wadannan su ne wasu misalai na PPI:
- Aciphex
- Dexilent
- Kapidex
- Nexium
- Prevacid
- Prilosec
- Protonix
- Zegerid
Kodayake ana daukar nauyin PPI lafiya, sunyi ƙananan haɗari na ciwon huhu, da yiwuwar hadarin C wuya .
Menene SIBO?
SIBO wani yanayin ne wanda akwai kwayar cuta mai yawa a cikin ƙwayar hanji . Wadannan kwayoyin suna aiki akan carbohydrates da kuke ci, suna haifar da furotin da ƙumburi a cikin hanji. Kwayoyin cutar SIBO sun hada da:
- Abun ciki na ciki
- Ruwan jini
- Diarrhea
- Tsinkaya
- Flatulence
Hanya tsakanin IBS da SIBO ya kasance abin rikici. Wannan shi ne saboda wani ɓangare, don matsaloli tare da ganewar asali na SIBO.
Za a iya gane mahimmancin ƙwarewa ta hanyar ci gaba da al'adu ta jiki, duk da haka, a aikace, marasa lafiya suna iya bincikar su ta amfani da gwajin numfashi na jini , ƙananan ƙazantawa, amma gwajin da ba a dogara ba. Kodayake wasu ƙididdiga suna da kyau sosai dangane da farfadowa tsakanin IBS da SIBO, ya fi yiwuwa SIBO taka muhimmiyar rawa ne kawai a cikin sassan marasa lafiya na IBS.
Matsalar ita ce ba kowa ba ne ya yarda da SIBO wanda yake cutar. Mutane da yawa na iya samun shaidar SIBO ba tare da wani alamu ba. Saboda haka ba a fahimci SIBO sosai ba kuma mafi yawan abin da za'a iya fada game da shi shine cewa kallo ne da aka yi amfani dashi a lokaci don gano zancen alamun mutum.
Bincike a kan Mawuyacin Hanya tsakanin Amfani na PPI da SIBO
Ka'idar da PPI ta yi amfani da shi wajen bunkasa SIBO ya dogara akan gaskiyar ciki shine ɗayan dalilai da zasu hana yaduwar kwayoyin cutar cikin ƙananan hanji. Sabili da haka, ƙwayar ciki mai ciki wanda ya haifar da PPI, yayin da yake yin aiki da ƙwaƙwalwar ƙwayar ƙwannafi da ƙwayar cuta, yana iya haifar da matsala a ƙasa a cikin tsarin narkewa .
Hakika, bincike ya gano cewa ragewa a ciki zai iya ƙara yawan kwayoyin cutar cikin ƙwayar ƙwayar. Abinda ba haka yake ba, shine ko wannan karuwa ya haifar da cigaban SIBO da alamunta.
A cikin binciken daya, kusan rabin marasa lafiya da suka dauki PPI a kan dogon lokaci suna gwada tabbatacce ga SIBO. Abubuwan alamun su sun kara ƙaruwa a tsawon lokaci, tare da bayyanar cututtuka da farawa a matsayin m ga farkon watanni shida, amma kara zuwa matsakaici da kuma tsanani a tsawon lokaci.
Ruwan jini da cututtukan sune na farko sunyi alamun bayyanar cutar, yayin da ƙananan marasa lafiya suka nuna asusu da kuma ciwon ciki.
A cikin karamin binciken, mutanen da basu da GERD (NERD) ba tare da raunin ba, kuma wadanda ba su bayar da rahoto ba, an ba da alamun PPI ga watanni shida. Bayan makonni takwas na jiyya, kusan rabin marasa lafiya sun yi gunaguni, yayin da ƙananan lambobi suka yi kuka game da flatulence, ciwon ciki, da kuma zawo. Bayan watanni shida na jiyya, kimanin kashi ɗaya cikin hudu na marasa lafiya sun gwada tabbatacce ga SIBO tare da gwajin numfashi, kuma kimanin kashi ɗaya cikin biyar na marasa lafiya sun sadu da ka'idoji don ganewar IBS .
Wani maganin bincike game da batun ya gano cewa akwai alamar shaidar haɗin PPI / SIBO a cikin binciken da ya yi amfani da al'adu don maganin SIBO, amma ba a wadanda suka yi amfani da gwaji ba. A bayyane yake, ana buƙatar karin bincike, tare da ƙarin haɓakawa akan yadda aka gano SIBO.
Layin Ƙasa
Har sai an fahimci SIBO mafi kyau, ko kuma an gwada gwaje-gwajen gwaji mafi mahimmanci, ba za a iya tabbatar da cewa akwai alamar PPI / SIBO / IBS ba. Idan kana da damuwa game da haɗin kai tsakanin PPI da IBS, tattauna batun tare da likitanka.
Sources:
Kwatanta, D., da.al. "Hanyoyin maganin PPI na dogon lokaci akan samar da cututtukan zuciya da SIBO." Jarida ta Turai na Binciken Bincike 2011 41: 380-386.
Johnson, D. & Oldfield, E. "Hanyoyin da Aka Bayyana Bayanai da Rarraba na Mai Gwanin Tsuntsauran Tsaro na Tsare-Tsaren Yi amfani da: Bayyana Shaidar" Gastroenterology Clinic da Hepatology 2013 11: 458-464.
Lo, W. & Walter, W. "Proton Pump Inhibitor Use and Risk of Small Intestinal Injinization Overgrowth: A Meta-Analysis" Clinical Gastroenterology da Hepatology 2013 11: 483-490.
Lombardo, L., et.al. "Ƙarin Rashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙwayar Ciwon Kwayoyin cuta A Cikin Gidawar Cibiyar Pulluɗa ta Proton" Clinical Gastroenterology and Hepatology 2010 8: 504-508.
Minocha, A. & Adamec, C. (2011) The Encyclopedia of the Digestive System and Disposers Disorders (2nd Ed.) New York: Facts on File.