Samun CF Gene Ba Ya Ma'anar Kuna Da Fibrosis Tsari
Cystic fibrosis shine cutar da aka haifa wanda ke haifar da ciwon huhu da cututtuka na sinus, rashin cin nasara a matsayin jarirai da ƙwayoyin cuta irin su mai yalwaci, daɗaɗɗo daga fatalwar malabsorption a cikin guttu ko maƙarƙashiya mai tsanani.
Bari mu binciki irin gadon da aka samu na cystic fibrosis, kazalika da yiwuwar kididdigar yarinyar da ke bunkasa CF idan iyayensu biyu masu ba da tallafin CF ne.
Cystic Fibrosis: Cututtuka da ƙwayar cuta ta Mutosomal
Kowane mutum yana da nau'i nau'i nau'i nau'i nau'i biyu na chromosomes a kowace tantanin halitta. Daga waɗannan nau'i nau'i nau'i nau'i nau'i biyu, nau'in biyu shine jima'i na chromosomes (X chromosome da Y chromosome) da sauran nau'in nau'i biyu na chromosomes an kira su autosomes.
Kowace ƙungiyar biyu suna da nau'o'in kwayoyin guda ɗaya, amma ba dole ba ne daidai da lambar jinsi guda. Alal misali, dukkanin chromosomes a cikin biyu wadanda suke ƙayyade launin gashi zasu ƙunshi jigon launi, amma ɗayan yana iya zama launin ruwan kasa da sauran launin launi.
Cystic fibrosis an lalacewa ta hanyar maye gurbin gwargwadon tsarin gwanin fibrosis transmembrane (CFTR). Idan kai mai dauke da CF ne, yana nufin cewa daya daga cikin kwayoyin ka na CFTR na al'ada ne, ɗayan kuma yana dauke da maye gurbin da aka sani don haifar da cystic fibrosis.
Cutar fibrosis kawai yakan faru ne a yayin da duka kofe guda guda na CFTR sun ƙunshi maye gurbin - wannan shine dalilin da ya sa ake kira cystic fibrosis da ciwon magungunan autosomal, a maimakon tsayayya da cutar da ta fi dacewa da ita (wanda kawai ana buƙatar guda ɗaya daga cikin kwayar halitta don ci gaba da cutar) .
Kwararru shine idan kai da abokin tarayyar ku abokan cinikin CF ne, zaka iya sanya CF zuwa ga yaro. Wannan shi ne saboda yaro zai sami gado daya daga kowane ɗayan daga gare ku, kuma ɗaya daga abokinku. Idan yaro ya sami duka kololin chromosome wanda ke dauke da kamfanonin CFTR da suka canza, za su sami takardun mutane biyu da za a haifa tare da cystic fibrosis.
Idan yaro ya karbi chromosome wanda ya rage daga daya daga cikin ku da kuma al'ada daga ɗayan, zasu zama mai dauke da CF, amma ba su da cystic fibrosis. Idan yaron ya gaji chromosome na biyu daga gare ku, zai sami takardun al'ada guda biyu, ma'ana ba ya ɗauka ko kuma yana da CF.
Fibrosis na Cystic: Yanayi na Ƙididdiga
Ga wata hanya don duba abin da ake nufi ya kasance mai ɗauka na CF.
Hannun haɗuwa da dillalai biyu na CF zasu iya ba wa ɗansu su ne:
- Hanyar CFTR daga iyaye + maye gurbin daga baba = mota
- Dalilai na CFTR daga iyaye na mutuntaka daga masihu = mota
- Bada al'ada CFTR daga uwa + al'ada CFTR daga baba = ba mai ɗaukar hoto ba kuma ba shi da CF
- Mutunta CFTR daga Iya + mutunta CFTR daga baba = cystic fibrosis
Idan kai da abokin tarayyarku duka masu sufuri ne, ɗayanku na da kashi 25 cikin dari na samun CF, kashi 50 bisa dari na damar kasancewa mai ɗaukar hoto, kuma kashi 25 cikin dari na dama ba tare da ɗaukar CF ba.
Idan abokin tarayya ba abokin tarayya ba ne, zai zama ba zai iya yiwuwa yaro ya sami CF ba domin yana iya samun asali na al'ada na CFTR daga abokinka. Duk da haka, idan yaro ya karbi lamirin CFTR daga gare ku, shi ko ita za su samu kashi 25 cikin dari na kasancewa mai hawa. A wannan yanayin, ɗayanku zai iya ba da alamar kamfanonin CF ga 'ya'yansu.
Abin da ake nufi don zama mai kiwon lafiya
Idan kun kasance mai kula da CF, ba za ku sami alamun bayyanar cututtuka na ƙwayar cuta ba kuma kada ku damu da inganta cutar. Bugu da ƙari, kasancewa mai ɗaukar kaya na CF bazai rage hankalinka ba ko ƙuntata ka a kowane hanya (banda shirin iyali).
Lokacin da kuka fara tunanin tunanin haihuwa , ku da abokin tarayyarku su nemi shawara ta kodayake don ƙayyade haɗarin haɗarin wucewa na CF ga 'ya'yanku masu zuwa. Musamman ma, za ka iya ganin idan kai da abokin tarayyarku abokan cinikin CF ne ta hanyar jarabawar jini don bincika samfurin CF.
Kalma Daga
Tsarin da za a sani shine kafin kafin shirye-shiryen jarrabawar yara, yawancin mutane ba su san cewa suna da CF har sai suna da alamun bayyanar.
Yanzu, idan jariri yana da gwajin gwaji mai kyau na CF, zai koyi wata gwagwarmaya ta chloride don tabbatar da ganewar asali na CF.
Tare da gwagwarmaya ta gwajin chloride, an auna gishirin abun ciki na gumi na jariri. Mutane da CF suna da mummunan mataki na gishiri a cikin gumi saboda nauyin gyarshe mai lalata.
Tare da ganewar asalin da suka gabata, kulawa a karkashin kungiyar kiwon lafiya ta CF na iya farawa da wuri. Ƙungiyar ta ƙunshi likitoci (musamman ma likitan kwantar da hankali tare da gwaninta a CF), masu jinya, likita, likita mai kwakwalwa, mai ilimin likitancin jiki, masanin kimiyya, da kuma ma'aikacin zamantakewa.
> Sources:
> Torpy JM, Lynm C, Glass RM. Cystic fibrosis. JAMA haƙuri Page. JAMA . 2009; 302 (10): 1130.
> Jami'ar Virginia Health System. (2016). Cystic Fibrosis.