Nicotine zai haifar da ciwon daji ko ya sa ciwon daji zai yada? Yaya tasirin Nicotine ke da shi akan maganin ciwon daji? Yayinda karin kayan shan taba da ke dauke da nicotine ya zama samuwa, wadannan sune tambayoyi masu muhimmanci. A daya daga cikin mahimmanci shine amfanar maye gurbin nicotine - zai iya taimakawa mutane suyi wani al'ada da aka sani da zai haifar da ciwon daji (da kuma sauran cututtuka). A wasu lokuta mutane ne da ke nuna cewa nicotine na iya zama m da kuma an yi amfani dashi a matsayin kwari.
Hanyoyin Nicotine akan Kankara
Don amsa wannan tambaya - muhimmancin nicotine game da ciwon daji - dole ne a rushe wannan tambaya a cikin batutuwan da dama. Saboda haka, ya kamata mu bincika muhimmancin nicotine a cikin wadannan:
- Tsuntsar Tumor ko Mutagenicity - Wannan yana nufin ikon abu don haifar da lalacewa (maye gurbi a cikin DNA) wajibi ne don canza salon tantanin halitta a cikin kwayar cututtuka .
- Rawanin Tumor / Ciwon Tumor - Wannan yana nufin ikon abu don haifar da ciwon tumo riga ya kasance don bunkasa da sauri da / ko yada (metastasize) zuwa wasu sassa na jiki da sauri.
- Dama akan Ciwon Kankara - Wannan yana nufin yadda wani abu zai iya kasancewa akan maganin ciwon daji, misali, idan wani abu ya hana ko ya hana aikin maganin ƙwayar cutar shan magani.
Matsayi na Nicotine a Ciwon daji
Ko da yake ba a gudanar da nazarin akan duk wani tasiri na nicotine a kan dukkan ciwon daji ba. Kuma, yawancin karatun da aka yi a yau an yi a kan ƙwayoyi, berayen, ko kuma kwayoyin cututtuka da suka girma a cikin Lab, mun san wadannan:
- Hanyoyin Nicotine akan Gyara Tumor ko Mutagenicity - Binciken da aka yi a baya ya nuna cewa nicotine na da ayyukan mutagenic da ci gaba da tumo. Akwai kuma shaida cewa nicotine zai iya haifar da lalata DNA-irin lalacewar da zai iya haifar da ciwon daji. Akwai kuma shaida cewa nicotine yana haifar da tsarin carcinogenesis-ma'anar cewa ingantaccen kwayar halitta zai zama mai karba a mayar da martani ga wani abu. Har ila yau, wannan ba yana nufin ba mai hatsari ga wadanda ba tare da ciwon daji ba. Abubuwan da ke ƙasa zasu iya faruwa a yayin da ciwon daji ke samuwa amma ba'a gano shi ba tukuna.
- Sakamakon sakamako da cigaba da tumo - Yayin da nicotine bazai da alhakin ƙwayoyin farko a cikin ƙwayar cutar, wasu ƙarin bincike sun nuna cewa da zarar wani ciwon daji ya taso, nicotine zai iya inganta ci gaban ƙwayar. Alal misali, an gano nicotine don inganta mummunan ciwon daji na pancreatic a cikin mice. Haka kuma an samo shi don inganta yaduwa, mamayewa, da kuma ƙaura da kwayoyin tumo da cutar kanjamau.
- Dama akan Amsoshin Ciwon Cutar Cancer - An gano Nicotine don magance wasu jiyya don ciwon daji, wanda zai iya nufin cewa nicotine zai iya rage yawan ciwon daji daga ciwon daji. Alal misali, nicotine na iya inganta juriya ga maganin ƙwayoyin cutar shan magani na Platinol (cisplatin) a cikin kwayoyin cutar kanjamau.
Yana da muhimmanci a lura da cewa, a mafi yawan waɗannan nazarin, an kwatanta nicotine daban daga taba shan taba don tabbatar da cewa sakamakon ne saboda nicotine kadai maimakon wasu abubuwa dake cikin taba.
Ta yaya Nicotine keyi don inganta Ciwon Ƙwayar Cutar Canji kuma yadawa da rage Rashin Jiyya
Akwai hanyoyi daban-daban da aka gano nicotine don tasiri da girma da yaduwar ciwon daji.
Wadannan sun haɗa da:
- Ƙara ƙarfafa fararen ciwon daji (kamar yadda muka gani a sama).
- Yada yawan ciwon tumo (ta hanyar samar da sunadarai da ke da alhakin radiyo da kuma girma).
- Gudanar da ciwon daji (misali, ta hanyar inganta motility na ciwon daji (kamar yadda aka ambata a kasa).
- Hanyar angiogenesis - Nicotine na iya bunkasa iyawar ciwon daji don samar da sabon jini da ake buƙata don ci gaba da hana ƙwayar halitta na tsofaffi ko maras kyau (apoptosis.)
- Hanyar damuwa - Ta hanyar hanyar motsa jiki daban-daban, nicotine na iya haifar da ƙwayar ƙwayar zama maras nauyi ga ma'aikatan chemotherapy.
Kodayake kwatanta hanyoyin da suka dace daidai da fasaha da kuma bayan wannan labarin, wasu misalan hanyoyin da aka gano nicotine don inganta ci gaban da yaduwar cututtuka sun haɗa da:
- Nicotine na iya yin aiki ta hanyar haɗin tare da masu karɓa da ake kira masu karɓa na nicotinic acetylcholine (nAChRs.) A gaskiya, wannan ita ce hanyar da nicotine ke jaraba. Ta hanyar kunna wadannan masu amfani da nicotine zasu iya ƙarfafa ciwon ciwon sukari, don inganta jigilar jini da ake bukata don ciwon sukari su yi girma ( angiogenesis ) da kuma hana mutuwa (apoptosis) na kwayoyin ciwon daji. Tun da akwai bambanci na masu karɓar acetylcholine na nicotinic tsakanin mutane daban-daban, waɗannan abubuwa zasu iya bambanta tsakanin mutane daban-daban. (Abin sha'awa shine, dabarun nicotine mai karfi ya danganta da babban cutar kanji.)
- Nicotine ta karfafa nau'in gina jiki wanda ake kira beta-arrest-1. Wannan furotin, ta biyun, yana inganta ƙwayar wasu kwayoyin cutar kanjamau wanda ya ba su damar yadawa da kuma mamaye sauƙi.
Cancers da aka haɗa zuwa Nicotine a wasu hanyoyi
An yi nazarin sakamako na nicotine a kan farawa, ci gaba, da amsawa ga magani ba tare da duk wani ciwon daji ba, amma akwai shaida cewa nicotine na iya zama mummunar aiki a akalla hanya ɗaya don wadannan cututtuka:
- Ƙananan ciwon huhu na huhu
- Magungunan ciwon huhu na kananan kwayoyin cutar
- Ƙunƙarar kai da wuyansa
- Ciwon gastric (ciwon ciwon ciki)
- Ciwon daji na Pancreatic
- Gallbladder ciwon daji
- Ciwon daji
- Ciwon kankara
- Ciwon daji na nono
- Ciwon daji
- Ciwon daji na bladder
- Maganin ciwon cizon daji (ƙwayar cutar ciwon jini)
Sources:
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