Berberine wani sinadaran ne da aka gano a yawancin ganye, irin su haushi, asalinsu, rhizomes na tsire-tsire da aka samu a fadin duniya, da kuma ƙarin kayan abinci a cikin shaguna na abinci. Amfanin lafiya na berberine an san shi tsawon ƙarni da dama kuma ana amfani dasu don magance yanayin kiwon lafiya da dama a cikin likitancin Indiya da na kasar Sin, wanda ya kasance daga cutar ciwon sukari zuwa cututtuka.
Saboda launin rawaya, wasu al'adu sunyi amfani dashi don yin yaduwa.
A cikin 'yan shekarun nan, an yi binciken berberine daga wasu tsire-tsire a cikin maganin kumburi, ciwon daji, ciwon zuciya da ciwon zuciya. Akwai wasu shaidu da suke nuna cewa berberine na iya zama tasiri a rage yawan cholesterol da matakan triglyceride.
Binciken da ke faruwa a yanzu ya nuna alƙawari
Kodayake akwai wasu nazarin ɗan adam da ke nazarin sakamakon berberine a kan matakan lipid , yawancin waɗannan nazarin sun kasance a cikin ƙuƙwalwa da ƙwayoyi. An samo berberine a cikin wadannan nazarin daga wasu ganye, ciki har da tushen zinari da Huanglian.
A cikin nazarin dabba, an yi amfani da berberine a ko'ina a tsakanin 100 da 250 MG / kg na jiki a kowace rana. Berberine ya bayyana ga ƙananan matakan cholesterol zuwa ƙasa zuwa 31%. Bugu da ƙari, an sauke matakan triglyceride kusan kusan 32% kuma an saukar da matakan cholesterol LDL 25%.
Ko da yake an jarraba HDL , berberine ba ya bayyana ya shafi shi sosai ba.
Bayanan nazarin ɗan adam da aka yi nazarin berberine ya fito ya sake yin nazarin binciken da aka gudanar a cikin dabbobi. Berberine 500 MG da aka yi wa mutane tare da high cholesterol matakin biyu zuwa sau uku a kowace rana har zuwa watanni uku. A sakamakon haka, an ƙaddamar da matakan cholesterol zuwa kashi 29%.
Triglyceride da LDL cholesterol matakan kuma rage saboda sakamakon ciwon berberine. Alal misali, an saukar da matakan cholesterol LDL da kashi 21%, yayin da matakan triglyceride sun sauke ta ko'ina tsakanin 22 da 35%. Matsakanin HDL, a gefe guda, bai bayyana ya canza da muhimmanci tare da kariyar berberine ba.
Ta yaya Berberine Lower Cholesterol?
Kodayake hanyar da berberine ke aiki a rage yawan cholesterol ba a sani ba, masana kimiyya suna da mahimmancin ra'ayoyin akan wannan bisa ga nazarin kwanan nan. An yi tunanin cewa berberine yana da ikon ƙaruwa yawan masu karɓar LDL a cikin hanta, wanda zai taimaka wajen kara yawan LDL cholesterol daga jiki. Berberine ma ya nuna aiki a kan hanyoyi masu alamar shiga cikin ƙwayoyin ƙwayoyin cuta. An kuma nuna cewa Berberine ya yi daidai da nau'o'i na jiki ta hanyar hana yin amfani da lipids daga ƙananan hanji.
Ya kamata ku dauki Berberine zuwa ƙananan cholesterol?
Nazarin nazarin yin amfani da berberine don rage ƙwayar cholesterol ya bayyana alamar rahama, duk da haka, ana buƙatar ƙarin bincike kafin a iya hada shi a matsayin mai ba da shawarar rage yawan ƙwayar cholesterol.
Kada a ba Berberine ga jarirai, saboda zai iya haifar da lalacewar kwakwalwa, ko kuma ga mata masu ciki da mata masu shan nono (zai iya lalata tayin ko jariri).
Berberine ta kanta yana da wuya a samu a matsayin kari don ɗaukar ka lipids. Duk da haka, yawancin kayan lambu da tsire-tsire suna samuwa ne na kasuwanni wanda ya ƙunshi yawancin berberine, ciki har da:
- Goldenseal tushen ( Hydrastis canadensis L )
- Tushen innabi na Ohio ( Berberis aquifolium )
- Barberry ( Berberis vulgaris )
- Huanglian ( Coptis chiensis )
Kwayar berberine ta bambanta a tsakanin kowane tsire-tsire. Alal misali, zinariyaenseal na iya ƙunsar ko'ina a tsakanin 1% da 6% na berberine. Saboda haka, kuna buƙatar duba lakabin kari don lura da abun ciki na berberine, maimakon yawan yawan ganye, a kowace kwamfutar hannu.
Don ganin sakamakon ciwon cholesterol a cikin nazarin ɗan adam, kuna buƙatar cinye mintin 500 na berberine sau biyu zuwa sau uku a rana.
Kodayake sauƙin m, ya kamata ka tuntuɓi mai ba da sabis na kiwon lafiya kafin ka ƙara berberine - ko duk abincin da ke dauke da wannan sinadarin - ga tsarin gurɓin ka. Sakamakon sakamakon da aka ruwaito tare da samfurori da ke dauke da berberine sun hada da ciwon kai, na ciki mai zurfi, da kuma tashin hankali. Wadannan cututtuka akan wasu sha'anin lafiyar jiki ba a san su ba, kuma ba a san ko da kariyar ciwon hade da ciwon daji na iya haɗawa da wasu magunguna da kake dauka.
Sources:
Abidi P, Chen W, Kraemer FB, Liu J. Zamanin magani na zane-zane na halitta ne na LDL-lowering tare da ƙananan abubuwa da aka saba da su da kuma sabon tsarin aikin. J Lipid Res 2006; 47: 2134-2147.
Cicero AFG, Erkek S. Berberine: sakamako na rayuwa da na zuciya da na kwayoyin zuciya a cikin gwaji da kuma gwaji. Nutr Diet Supp. 2009; 1: 1-10
Na'urar Magana. (2015). Berberine [Monograph].
Pirillo A, Catapano AL. Berberine, wata shuka alkaloid tare da lipid da glucose-lowering Properties: daga shaida a vitro zuwa binciken asibiti. Atherosclerosis 2015; 243: 449-461.