Wani tambayoyin yakan taso a cikin aikin likita na yau da kullum. Masanan sun tambayi, "Ina da tarihin cutar ciwon gurgu, amma matakan testosterone suna da rauni. Zan iya daukar testosterone? "Amsar amsar da likitoci da dama ke bayar shine" ba shakka ba "- testosterone zai zama kamar makamashin a kan wuta kuma ya hanzarta cigaban ciwon daji.
Amma wannan gaskiya ne? Amsar ita ce mai cancanta "eh," amma akwai akalla yanayi hudu tare da wasu waɗanda za a yi magana a kasa.
Duk da haka, kafin mu bayyana yanayin da maza da ke fama da ciwon karuwanci na iya yin la'akari da ɗaukar testosterone, muna bukatar mu tattauna yadda za'a gwada gwajin jini da za a auna testosterone. Mene ne ainihin bakin kofa wanda yake bayyana lokacin da matakin testosterone a cikin jini ya wuce ƙasa?
Testosterone Laboratory Testing Blood
Akwai wasu batutuwa da suka danganci gwajin testosterone a cikin jini. Na farko, yawan kwayoyin cutar testosterone sun fi girma da safe da kuma ƙananan maraice. Wani gwajin da aka kai a karfe 4 na yamma wanda "low" yana iya kasancewa a waje na al'ada saboda ranar da aka dauki jini.
Na biyu, akwai hakikanin gwajin testosterone guda biyu: jimlar testosterone da free testosterone. Yawancin gwaje-gwaje na yau da kullum kawai auna yawan kwayoyin testosterone. Duk da haka, kyautar testosterone kyauta shine ma'auni mafi nauyin aikin aikin physiologic na testosterone. Wannan ya ce, masana a fili sun fahimci cewa haɗin tsakanin matakan ƙididdigar ƙwayoyin testosterone kyauta da kuma tunanin da mutane ke yi game da makamashi da libido su ne sau da yawa.
Wasu maza tare da ƙananan testosterone kyauta suna jin lafiya.
Tabbatar da matsayin mutum na testosterone da kuma yanke shawarar game da bukatar yin maganin testosterone kada ya dogara ne kawai akan matakin testosterone cikin jini. Yana da mahimmanci don kafa shawarar da za a yi amfani da testosterone a kan mutum na bayyanar cututtuka.
Mene ne ma'anar bada testosterone ga wani kawai don gyara abin da ya rage a sakamakon gwajin jini idan mai haƙuri ya ji dadi?
Testosterone Far da Ciwon ƙwayar cuta
Yanzu bari muyi magana game da yanayin da za a iya ba da maganin testosterone a cikin mutumin da ke da ciwon sankarar sankara.
Matsayi na farko shine bada testosterone ga maza da ƙananan ciwon ƙwayar cuta. Wasu cututtuka na ciwon sankara suna da ƙananan ƙananan basu zama marasa lahani. Wadannan nau'in ciwon gurguwar cutar karuwanci ba su yadawa kuma ya kamata a kira su ciwon ciwon sukari. Abin takaici, an ba da kalmar maganganun "ciwon daji" ba daidai ba ga waɗannan nau'i na ciwon daji na ƙwayar ciwon daji a shekarun da suka wuce kuma wannan manufar kiran su ciwon daji yana rayuwa har yau.
Matsayi na biyu inda bada testosterone zai kasance lafiya mai lafiya shi ne lokacin da mutane sun rigaya sun fara farfadowa tare da tiyata ko radiation kuma sun bayyana sun warke. Bayan lokacin jiran dacewa a wani wuri a tsakanin shekaru biyu da biyar, haɗarin ciwon daji ya sake zama maras kyau. Tsoro na yin amfani da testosterone a cikin wannan halin da ake ciki alama ba tushe.
Halin na uku ya auku a cikin maza da ciwon ciwon karuwanci wanda suka sake komawa bayan tiyata ko radiation. Wannan alama ce ta alamar ta hanyar cigaba da matakin PSA cikin jini.
A al'ada, ana gudanar da waɗannan mutane tare da maganin kwayoyin testosterone masu rikitarwa irin su Lupron ko Firmagon. Nazarin ya nuna cewa dogon lokaci maganin ciwon daji yana daidai ne ta yin amfani da launi na Lupron ko ci gaba da Lupron.
Haka ne, wannan sauti ba ta da kyau, amma yana da lafiya don dakatar da maganin maganin anticancer da kuma hutawa. Da zarar an dakatar da magani, aikin samar da kwayoyin testosterone daga kwayoyin halitta ya samar da matakan testosterone na al'ada cikin jini. Duk da haka, wani lokaci testosterone ya kasance mai rauni, musamman a cikin tsofaffi maza. Lupron na baya ya sa waɗannan masu binciken su barci.
Lokacin da samar da sinadarin testosterone ba zai sake ci gaba ba, yana da kyau a yi la'akari da samar da testosterone. Bayan haka, tun da an tabbatar da cewa barin izinin barin kwayoyin testosterone daga cikin kwayoyin halitta lafiya, to yaya ba zai zama mai lafiya don gudanar da kwayar cutar kwayoyin halitta ba a cikin allurai wanda aka tsara don cimma daidai matakan jini na testosterone wanda aka samu ta hanyar kwayoyin?
Halin na hudu da za a yi la'akari shi ne lokacin da matakan testosterone suna da rauni a cikin mutumin da ke da ciwon sankarar sankara wanda yake da mummunan ciwo na jiki ko tsokawar tsoka da aka ci gaba da haɗuwa da rauni da lalata. Wannan labari zai iya faruwa a cikin maza da shekarun tsufa ko kuma saboda wasu cututtuka masu tsanani. Lokacin da mutane suka raunana (saboda wasu marasa ciwon daji) zai iya zama mafi haɗari don riƙe testosterone fiye da ba shi, ko da yake cutar cancer na prostate zai iya girma da sauri saboda tsinkaya ga testosterone. Ya kamata mu tuna cewa ko da magungunan ciwon ciwon sukari "mummunan" sun kasance a cikin rashin girma. Idan an yanke shawara don fara testosterone, za a iya kula da ci gaba na ciwon hankali tare da nazarin jini na PSA da ƙuƙwalwar jiki. Idan waɗannan gwaje-gwaje sun nuna cewa ciwon daji ke ci gaba da sauri, za a iya dakatar da kwayar cutar testosterone tare da tsammanin ciwon daji zai daina ci gaba ko cigaba bayan da aka dakatar da testosterone.
Me ya sa rikici?
Rashin rikici game da yin amfani da maganin gurgun kwayoyin cutar a cikin maza da ciwon sankarar da aka sani shine sakamakon ciwon ciwon gurguwar ƙwayar ƙwayar cuta ba ƙima ce ba. Akwai ƙananan, matsakaici, da siffofi masu daraja; ciwon daji da kuma ciwon daji na cin zarafi ; iri iri iri iri iri masu tsauraran kwayoyin halitta wadanda basu da mahimmanci ga maganin hormone. Wata yarjejeniya guda ɗaya ba zai dace da kowane ɗayan ƙwayar cutar ciwon sankara ba.
Saboda haka, yanke shawara don fara testosterone, don haka, ya sauko zuwa al'amura biyu. Na takaitaccen bayani na farko da bayanin da aka kwatanta akan abubuwa hudu da suka faru a cikin maza da ciwon sankarar da ake kira prostate wanda ke da ƙananan testosterone kuma zai iya amfana ta yin amfani da testosterone mai yawa. Batu na biyu ya shafi haɗari na yin amfani da testosterone a cikin wani namiji mai lafiya wanda ba shi da ciwon ciwon gurgu. Nazarin ya nuna cewa bada testosterone ba shi da lafiya sosai-har ma a cikin maza da basu da wani ciwon gurguwar cutar ta prostate.
Matakan Testosterone a cikin jini suna karuwa da shekaru. Yawancin mutane sukan dace da wannan sauƙi a cikin testosterone ba tare da fuskantar wahala ba. Duk da haka, akwai wasu, sakamakon mummunar sakamako da rashin ciwon gurguntaccen ƙwayar cuta, musamman ma lokacin da aka kawar da testosterone. Wadannan sakamako na low testosterone sun hada da matakin ƙananan makamashi, rashin jima'i, motsa jiki, matsalolin ƙwaƙwalwar ajiya, wadata mai yawa, ƙarar nono, kuma wani lokacin, hanzari na asarar allura daga kasusuwa - watau osteoporosis. Duk wadannan mummunan sakamako na testosterone marasa ƙarfi za a iya jujjuya ta hanyar sake dawo da matakin gurguntaccen kwayar testosterone cikin jini.
Gwajin Cibiyar Nazarin Tsaro na Testosterone da Risks?
Ana iya samun maganin testosterone a cikin nau'o'in nau'i daban-daban, ciki har da yin amfani da injections, gels, da kuma transdermal faci. Aikace-aikace na jiyya yana da sauki. Duk da haka, kamar yadda muka gani a baya, farfadowa na testosterone ba tare da hadarin (ba daga hadarin yin amfani da shi a cikin maza da ciwon daji). Babbar damuwa daga maganin maye gurbin testosterone shine ci gaba da ƙididdigar jinin jini wanda ya fi yadda al'ada-lokaci na fasaha yana da babban halayen rubutu. Halin na hematocrit, sau da yawa sau da yawa kamar Hct, wani ɓangaren wani sashin jini, CBC ko ƙididdigar jini. Wani kalma na fasaha da za ka iya samowa wanda ke nuna ma'anar wannan ma'anar shi kamar high hematocrit shine " polycythemia ."
Girman ƙananan ƙuƙwalwar ƙuƙwalwa shine nufin jini ya zama mai ƙwaya (thickening of blood), wanda zai iya haifar da mummunan matsaloli irin su ciwon zuciya da shanyewa. Kula da hankali na hematocrit ya zama wajibi, sabili da haka, a cikin kowane shirin da za a maye gurbin testosterone. Ya kamata babban halayen halayya ya bunkasa yayin da ake ci gaba da maganin testosterone, wato, ya kamata basaltcrit ya tashi sama da kashi 50 cikin dari, wasu nau'ikan bukatun da za a aiwatar. Irin wannan matakan na iya haɗa da cirewar jini na lokaci akan aikin hawan jini ko yiwuwar ragewa a cikin jigilar testosterone.
Gudanar da gyaran maganin testosterone ya zama daidai, kuma a cikin maza ba tare da ciwon gurgunta ba, amfani da shi ya zama sananne. Kamar yadda muka gani a sama, ba duk wanda yake nazarin testosterone zai fuskanci irin amfanin da za'a iya tsammani-amfanin kamar karuwa a libido ko ƙara yawan matakan makamashi.
Bayan shekaru da yawa na kwarewa na ba da ilimin testosterone ga mutane da yawa, na koyi cewa akwai matukar tasiri a hanyar da mutane za su amsa. Wasu lokuta tasiri na testosterone yana da sauri da ban mamaki. A wasu mutane, koda bayan an kammala fitinar watanni shida, ana iya samun amfani mai mahimmanci.
Hanyar hanyar da za ta tantance ko wani mutum zai amfana daga testosterone shi ne ya fara gwaji kuma ya lura da abin da ke faruwa a tsawon watanni shida ko fiye. Ana buƙatar tsawon lokacin fitina don sanin idan sakamako mai amfani zai faru. Testosterone ba zai haifar da sakamako mai sauri ba kamar wasu kwayoyin halitta, kamar adrenaline, alal misali.
Nemo Ciwon Cutar Ciwonku
Yawancin abin da muka tattauna a daidai yake kuma yawancin masu aikin likita da kuma likitoci na al'ada sun saba da bayar da maganin testosterone ga maza ba tare da ciwo ba. Halin halin da ake ciki, kamar yadda aka gani a sama, yana cikin maza da ke aiki ko a baya sun kamu da ciwo da karuwanci. Bayan haka, ƙwayar maganin testosterone yana daya daga cikin hanyoyin da ya fi dacewa don magance cutar ciwon gurba. Yaya, saboda haka, za a iya samun ciwon ƙarin testosterone a cikin maza da ciwon karuwanci ba cutar? Amsar ita ce, irin ciwon daji na prostate ya kamata a bayyana a fili.
Magunguna na ciwon sankara suna iya rarraba zuwa manyan nau'i biyu - siffar marar lahani (musamman, waɗanda aka ƙaddara su zama na saita na shida ko žasa kamar yadda aka ƙaddara ta hanyar allurar maciji ko ta tiyata), da kuma sauran abubuwa masu mahimmanci, wanda an karu daga bakwai zuwa goma. Ƙarin dalilai irin su PSA da sakamakon sakamako daban-daban na iya shafar yanke shawara. A mafi yawancin lokuta, kimantawa ta likitan kwari na prostate zai zama wajibi ne don yanke shawarar karshe game da lafiyar samar da maganin testosterone ga mutumin da yake da tarihin ciwon kwari na prostate.
> Sources:
> AVEED ® (Bayyana Bayanai). Malvern, PA: Endo Pharmaceuticals Inc.
> Edelstein D, da Basaria S. "Testosterone undecanoate a cikin maganin namiji na hypogonadism." Kwararren masanin kwarewa a kan pharmacotherapy 11.12 (2010): 2095-2106.
> Eisenberg, ML. "Sanarwar maganin ƙwayar cutar ta Tostosterone da Ciwon daji na Ciwon Tsari". Labarin Jaridar Lafiya ta Jama'a 33.3 (2015): 125-129. PMC . Yanar gizo. 28 Mar. 2017.
> Pickles, T, et al. "Turawa na Testosterone bayan adjuvant da ciwon hawan ma'adinan da ke ciwon hawan karuwa na prostate carcinoma." Ciwon daji 94.2 (2002): 362-367.
> Matsananciyoyin matakin Testosterone suna da muhimmanci. Tattaunawa da Dr. Laurence Klotz ta Prostatepedia. http://pcri.org/insights-blog/2016/4/6/testosterone-levels-are-significant-.