Tambaya: Ya Kamata Ka Ɗauki CoQ10 tare da Statins?
Dikina ya sanya ni a cikin simastastatin don rage ƙananan cholesterol. Ina ganin in yarda da shi OK, amma na ji cewa idan kana shan maganin magunguna, ya kamata ku dauki CoQ10 don hana matsalolin tsoka. Shin gaskiya ne? Ya kamata in dauki CoQ10?
Amsa: Abin baƙin ciki, babu amsa mai mahimmanci ga wannan tambaya.
Duk da haka, shaidun shaidar asibiti da muke da ita sun nuna cewa CoQ10 baya taimakawa sosai, idan a kowane lokaci, don hana ko magance matsalolin tsoka da statins .
Mene Ne CoQ10?
CoQ10 - wanda aka fi sani da suna ubiquinone - wani coenzyme ne wanda ke taimakawa tsokoki samar da makamashi da suke buƙatar yin aiki. Duk da yake wasu binciken sun nuna cewa statins zasu iya rage adadin CoQ10 a cikin tsoka, wasu nazarin ba su samo raguwa a cikin matakan CoQ10 da statins ba. Don haka ko da tambaya game da ko ka'idodin shafi na CoQ10 ba duka cikakke ba ne. A kowane hali, mutane da yawa sun yi la'akari da cewa ƙananan matakai na CoQ10 zasu iya taimakawa wajen maganin myopathy (ciwon tsoka) wanda zai iya faruwa tare da statins . Don haka, wasu likitoci sun ba da umarnin karin CoQ10 tare da tsarin likita.
Menene Shaida akan CoQ10 da Dokoki?
An wallafa littattafai na likita a kan tambaya na CoQ10, da dalilai guda biyu.
Na farko, kamar yadda aka ambata, ba duk binciken da ya nuna ba cewa ka'idodin sun shafi matakan CoQ10 a cikin jikin tsoka kanta.
Kuma na biyu, nazarin da CoQ10 a cikin mutane da ke daukar jinsin suna da iyakancewa sosai. An ƙaddamar da ƙididdiga kaɗan, ƙananan, ƙididdigar gajeren lokaci, kuma sakamakon waɗannan ƙananan binciken kullum sun kasance abin takaici.
Nazarin binciken da aka gudanar a yanzu ya binciki ikon CoQ10 don magance ciwo mai tsoka.
Dalilin waɗannan binciken shine don sanin ko yin CoQ10 zai ba marasa lafiya da ciwon ciwon zuciya mai ci gaba da ci gaba da ci gaba. Wannan abu ne mai mahimmanci, domin idan ya zo ne don rage cututtukan zuciya kamar yadda ya kamata a sakamakon ƙwayoyin cholesterol, babu wani abu mai kyau wanda zai maye gurbin statins .
Wadannan binciken sun haifar da sakamakon rikici. Kwararrun gwaji a cikin marasa lafiya 32 da ciwon tsofaffin mahaifa sun nuna cewa, bayan kwanaki 30, waɗanda suka karbi CoQ10 suna da raguwa mai tsanani a cikin ciwon tsoka idan aka kwatanta da waɗanda aka bazu don su sami bitamin E. Ana duba kwanaki 30 na wannan binciken. matsalar, duk da haka, saboda yana ɗaukar fiye da kwanaki 30 don ƙarin haɗin CoQ10 ya shafi adadin CoQ10 a cikin tsokoki kansu. Bugu da ƙari kuma, da yawa irin wannan gwajin, tare da CoQ10 sun nuna rashin cigaba a cikin tsoka akan tsofaffin kwayoyin.
Don ƙoƙarin magance matsalar, an yi nazari kan meta-bincike a shekara ta 2015, yana nazarin gwaje-gwajen da aka samo. Wannan bincike bai samo wani amfani mai amfani idan an yi amfani da CoQ10 don magance cututtukan da aka yiwa mutum ba. Duk da haka, ingancin binciken da aka samo yana kasancewa batu, saboda haka ba za'a iya la'akari da sakamakon wannan maganin ba.
Yafi girma, gwajin gwagwarmaya na tsawon lokaci zai zama dole don samun mahimmanci akan wannan tambaya.
Babu wani daga cikin wannan, duk da haka, ainihin tambayarka, wato, ya kamata mutumin da yake daukar statins ya dauki CoQ10 don hana statin myopathy? Dalilin da na yi magana kawai game da yin amfani da CoQ10 don magance ciwon tsoka ta jiki shi ne cewa akwai akalla bayanai da ke magance wannan tambaya (kamar yadda ƙananan bayanan yana iya zama).
Amma idan yazo game da yin amfani da CoQ10 a matsayin ma'auni na ƙariya, shaidar da kawai take samuwa ne gaba daya anecdotal. Ba a buga jarrabawar gwagwarmayar bazata ba wanda ke magance wannan tambaya.
CoQ10 da Statins - Layin Ƙasa
Labaran ƙasa shine cewa babu wani kyakkyawan shaida, daga cikin gwaji na asibiti yana samuwa don nuna ko CoQ10 ko dai ya hana ko ya dace da maganin ciwon tsoka na stin. A lokaci guda kuma, ka'idar da CoQ10 zai iya taimakawa ya kasance yana da sha'awa sosai, kuma karatun da aka yi suna da iyakancewa a kan iyakarsu da tsawon lokaci. Bugu da ƙari, karɓar ƙarin CoQ10 (kamar yadda kowa ya san) ba shi da lahani.
Don haka idan kuna da sha'awar ƙoƙari, kuma za ku iya samunta, mafi yawan likitoci za su yi murmushi ba da karfi ga ra'ayin.
Idan kuna ciwon ciwon tsoka yayin da yake a kan kwayoyin, ya kamata ku yi magana da likitanku game da kokarin daya daga cikin kwayoyin kwayoyin da ake san su da wuya su haifar da matsaloli na muscle, wato, Lescol (fluvastatin) ko Pravachol (pravastatin). Har ila yau, tabbatar da cewa likitanku yana kula da aikin maganin thyroid da matakan bitamin D, tun da dai dai hypothyroidism ko rashin bitamin D zai sa likitan myopathy ya fi dacewa.
> Sources:
> Banach M, Serban C, Sahebkar A, et al. Hannun Coenzyme Q10 a kan Labaran Ƙungiyar Myopathy: Meta-Analysis of Randomized Controlled Trials. Mayo Clin Proc 2015; 90:24.
> Bookstaver DA, Burkhalter NA, Hatzigeorgiou C. Sakamakon Coenzyme Q10 Karin Ƙari a kan Magunguna da aka ƙaddara. Am J Cardiol 2012; 110: 526.
> Caso G, Kelly P, McNurlan MA, Lawson WE. Sakamakon Coenzyme q10 a kan Myopathic cututtuka a cikin marasa lafiya bi da tare da Statins. Am J Cardiol 2007; 99: 1409.
> Taylor BA, Inon L, White CM, Thompson PD. Wani gwajin Random na Coenzyme Q10 a cikin marasa lafiya tare da Tabbatar da Myopathy. Atherosclerosis 2015; 238: 329.