Duk da haka wani abu na asiri, sarcoidosis wani cututtuka ne wanda ba a sani ba - ko da yake amsawar rigakafi da jinsin mutum yana da muhimmanci. Sarcoidosis, wani lokaci ana kiranta sarcoid, yana kaiwa ga irin ƙin ƙonewa wanda ke iya ganewa a ƙarƙashin kwayar halitta kuma yana iya shafar jikin jiki daban-daban. Sarcoidosis zai iya shafar kowane sashi, amma zai fi dacewa da shafukan yanar gizo masu zuwa:
- Kwana
- Skin
- Lambobi na Lymph - musamman magungunan lymph a cikin kirji
Sarcoidosis kuma an san shi don yiwuwar rinjayar idanun da hanta. Mafi yawancin, zuciya da kwakwalwa na iya shafarwa, yana haifar da rikitarwa mai tsanani.
Daga yanayin kwayoyin halitta da kyallen takalma, alamar sarcoidosis shine wani abu da ake kira granuloma. Granulomas sune jerin tarin kwayoyin halitta wanda, a ƙarƙashin microscope, yayi kama da wadanda jiki ke amfani dasu don yaki da cututtuka irin su tarin fuka.
Ba kowa da sarcoidosis na buƙatar magani, kuma sau da yawa ya tafi ba tare da magani ba, amma a wasu lokuta, zai iya haifar da cutar mai tsanani. Lokacin da aka shafi aiki na kwaya, alal misali, ana amfani da kwayoyi daban-daban da aka tsara domin kawar da tsarin rigakafi.
Kwayar cututtuka na iya danganta da kwayoyin da ke cikin cutar, ko kuma akwai alamun bayyanar cututtuka irin su gajiya, zazzabi, ƙwayoyin lymph mai ƙumi, da asarar nauyi . Yin amfani da wutsiyoci ya zama na kowa kuma bayyanar cututtuka na iya haɗa da tarihin busassun ƙasa, rashin ƙarfi, numfashi ko zafi na kirji.
Wasu mutane tare da sarcoidosis sun inganta bayyanar cututtukan fatar jiki irin su rash da aka yi da ja ko duhu bumps.
Lymphoma
Lymphoma yana daya daga cikin "cututtukan jini," ko rashin lafiyar jini, wani lokaci wanda ya haɗa da leukemias da myeloma . Lymphoma ciwon ciwon daji ne na ƙwayoyin jini na lymphocyte. Akwai nau'o'in lymphoma da yawa.
Yawancin, amma ba duka ba, lymphomas farawa a cikin ƙananan lymph nodes.
Hanyoyin lymphoma guda biyu sune Hodgkin (HL) da lymphoma ba Hodgkin (NHL). Dukansu nau'o'in suna da nau'o'in iri da yawa a cikin ciki, tare da siffofin cututtuka daban-daban da kuma prognoses.
Hodgkin da lymphoma ba na Hodgkin na iya shafar ƙwayar lymph na kirji - yankin da ke kusa da zuciyar da ake kira mediastinum. Sarcoidosis ma akai-akai ya ƙunshi wannan yanki.
Sarcoidosis da Lymphoma
Shekaru da dama, masu bincike sunyi mamakin dangantakar dake tsakanin sarcoidosis da lymphoma. Wannan dangantaka ta kasance mai ban mamaki har ma a yau, don dalilai da yawa.
A cewar wani rukuni na masu bincike ciki har da Ishida da abokan aiki, "Mafi yawan kwayar lymphoma mai kama da sarcoidosis shine lymphoma Hodgkin, amma yaduwar babban lymphoma B-cell, lymphoma follicular, da kuma myeloma mai yawa na iya shiga cikin sarcoidosis-lymphoma syndrome. "An tsara kalmar" Sarcoid-lymphoma syndrome "don bayyana wadannan binciken.
Ƙunƙasar granulomas na sarcoidosis sune ƙayyadaddun tsari, jerin tsararru na kwayoyin da ke cikin kwayar cutar ta lymphocytes. A bayyane yake, lymphomas na iya amfani da "sarcoidal" granulomas a cikin ciwon daji - kuma wannan canji, ko da yake rare, anyi zaton yana iya nuna rashin lafiyar cutar ciwon daji, kuma ba cututtuka ba, sarcoidosis.
Takardun da aka buga a cikin shekarun da suka gabata sun lura cewa rarrabe tsakanin sarcoidal da ƙwayar cuta na iya zama matsala.
Dukansu sarcoidosis da lymphoma suna da damar "haskakawa" a kan PET scans, ƙara da ƙwarewar da kuma damar don rikice batun mahallin ga sauran. Masu bincike suna kira don kara nazarin don tsaftace aikace-aikace na asibiti na FDG-PET / CT a cikin marasa lafiya da sarcoidosis.
A takaice dai, ba a amsa tambayoyin da yawa game da sarcoidosis-lymphoma syndrome.
> Sources:
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Reich JM, Mullooly JP, Johnson RE. Haɗin bincike na malignancy-hade sarcoidosis. Chest. 1995; 107: 605-613
Ciwon Zuciya na Ƙasar da Ciwon Jiki. Menene Sarcoidosis? Samun shiga Janairu 2016.
Goswami T, Siddique S, Cohen P, Cheson BD. Sarcoid-lymphoma ciwon. Clin Lymphoma Myeloma Leuk . 2010; 10: 241-247.