Magunin injectable ya rage ciwon osteoarthritis gaba
Synvisc (hylan GF 20) wani ruwa ne mai ban sha'awa wanda aka samo daga wani abu da ake kira hyaluronan (hyaluronate sodium). Hyaluronan an samar da ita ta jiki a cikin jiki don taimakawa a saɗa gidajen. Nau'in da aka samo a Synvisc anyi shi ne daga abubuwa gelatinous da aka samo daga cikin kaza.
Ana amfani da Synvisc a cikin hanyar farfado da aka sani da haɓakawa wanda aka yi amfani da abu zuwa cikin haɗin gwiwa don taimakawa wajen ƙara lubrication.
Drug Overview
Synvisc injections an yarda don maganin osteoarthritis na gwiwa a cikin mutane da suka kasa amsa ga mafi mahimmanci farfadowa, ciki har da analgesics da ba da miyagun zažužžukan.
An kawo Synvisc a cikin allurar biyu-milliliter kai tsaye a cikin haɗin gwiwa. Ba'a amince da shi ba don kowane haɗin gwiwa ba tare da gwiwa ba. Synvisc an ba da shi a matsayin jerin jerin injections guda uku da aka kawo kowace mako. Don cimma sakamakon mafi kyawun, hawan gine-gine a cikin gwiwar gwiwa suna yawan cirewa kafin inuwa na farko.
Akwai wasu samfurin Synvisc, wanda aka sani da Synvisc-One, wanda aka gudanar a matsayin guda ɗaya, harbi shida.
An amince da Synvisc don amfani da Amurka da abinci a kan Agusta 8, 1997. Synvisc-Daya ya karbi takardar shaidar FDA a ranar 26 ga Fabrairu, 2009. Abubuwa masu rinjaye da suka hada da Synvisc sun hada da:
- Pain, kumburi, ko hawan gwiwa a gwiwa gwiwa
- Hadin gwiwa ("ruwa cikin gwiwa")
- Haɗin gwiwa jijiya ciwo
- Rash ko amya
- Fever
- Jiɗa
- Ciwon kai
- Dizziness
- Muscle cramps
- Wulo
Yawancin waɗannan bayyanar cututtuka suna da sauƙi a matsakaici a cikin tsanani kuma za su warware kan kansu ba tare da magani ba. Idan wani daga cikin alamun bayyanar ya ci gaba ko ciwo, kira likitanka nan da nan kamar yadda wannan zai iya zama alamar kamuwa da cuta ko rashin lafiya.
Kyakkyawan Synvisc a Cigaba Tarkon Hoto
An gudanar da gwaje-gwajen gwaji don tantance tasiri na Synvisc a cikin mutanen da ke da ciwon osteoarthritis na daya ko biyu. Mahalarta sun hada da mata 56 da maza 52 da shekarun da suka kai 62. Kowane ya kasa samun taimako tare da magungunan ƙwayoyin anti-inflammatory (NSAIDs) ko cortisone Shots .
A lokacin shari'ar, kowanne dan takara ya karbi Synvisc guda uku a cikin mako daya. An yi nazari akan daya, uku, shida, 12, 15, da 18 watanni. Binciken ya yi nazarin fahimtar jin daɗin jin dadi a tsakanin mahalarta nazarin kuma ya tabbatar da yadda tasirin ya kasance mai tasiri a jinkirta tayar da gwiwa gwiwa (TKR) .
Bayan kammala, masu binciken sun bayyana cewa kashi 72.6 cikin dari na marasa lafiya da aka bi da su tare da Synvisc sun guje wa aikin TKR a duk lokacin binciken. Duk da yake ba a yi la'akari da sakamako mai tsanani ba ko kuma lokaci mai tsawo, mutane takwas sun sami wani mummunar halayen ƙin ƙetarewa bayan injections. Ba wanda aka yi la'akari da tsanani.
Dangane da Cibiyar Yammacin Ontario da McMaster Osteoarthritis Index ( WOMAC ), kimanin kimanin kashi 20 cikin dari na shan wahala idan aka kwatanta da wadanda suke a kan placebo.
Osteoarthritis na gwiwa ne a yau mafi yawan maganin arthritis a Amurka, yana da kimanin mutane miliyan 13.7. Bisa ga binciken binciken, Synvisc ana daukar su mai lafiya da tasiri wajen magance ciwo da nakasa a cikin wannan jama'a kuma, idan aka yi amfani dashi daidai, zai iya taimakawa jinkirin yin aiki na tsawon shekaru uku ko fiye.
> Source:
> Cibiyar Abinci da Drug. (2008) "An gabatar da Synvisc-Ɗaya daga cikin taƙaitaccen Tsaro da Kwarewa." Silver Spring, Maryland.