Otrexup Yakanin Autoinjector ne kawai
Otrexup ( methotrexate ) wani abu ne mai sassaucin zuciya, guda-kashi autoinjector dauke da maganin maganin likitanci. Oterxup ya fara amincewa da FDA a ranar 11 ga Oktoba, 2013. Otrexup, wanda kamfanin Anatares Pharma, Inc. ne ya tsara, ya zama madadin hanyoyin da za a iya yin amfani da shi, da magungunan shinge wanda ke da inganci, ko wani jigon autoinjector, Rasuvo .
Shaidawa ga Otrexup
Otrexup, mai maganin maganin maganin analog ɗin analog, shine FDA-an yarda da shi don gudanar da mutane tare da mai tsanani, arthritis mai yaduwar cutar da kuma maganin ƙwararrun ƙwayoyin cuta na ƙwayoyin cuta na polyarticular wanda ke da rashin dacewar amsa ga farfadowa na farko. An kuma yarda da Otrexup don kula da bayyanar cututtuka da ke haɗuwa da tsanani, kawar da psoriasis a cikin tsofaffi waɗanda basu sami amsa ga sauran maganin. Otrexup ba a yarda da maganin cututtukan cututtuka ba.
Gudanarwa na Otrexup
Farawa allurai don methotrexate ne 7.5 MG sau ɗaya a mako daya ga mutane tare da rheumatoid arthritis, 10 MG / m2 sau ɗaya mako-mako na marasa lafiya tare da polyarticular yara idiopathic arthritis, da kuma 10 zuwa 25 MG sau ɗaya mako domin psoriasis. Otrexup ana gudanar da shi a matsayin mako daya, injection subcutaneous. Ana iya allura a cikin cinya ko ciki ta kowace hanya.
Otrexup yana samuwa a cikin allurai tsakanin 10 zuwa 25 MG a 5 MG increments.
Dole ne a yi amfani da wani tsari na hanya, ban da Otrexup, a cikin marasa lafiya da ke buƙatar bugun zuciya, intramuscular, intravenous, intra-arterial, ko intrathecal dosing, allurai kasa da 10 MG a mako, allurai fiye da 25 MG a mako, high-dose tsarin , ko gyare-gyaren gyare-gyare na kasa da 5 MG.
Contraindications
Otrexup kada a yi amfani da mata masu juna biyu, masu uwa masu yayewa, ko wadanda ke fama da cutar hanta ko kuma maye gurbi. Har ila yau, Otrexup ya kamata a kauce masa ta hanyar mutanen da ke fama da rashin daidaituwa, rashin jini a gabanin jini, ko sanannun sanadiyar hanya.
Hanyoyin Kasuwanci na Musamman
Otrexup yana hade da halayen halayen na yau da kullum, ciki har da: tashin zuciya, zafi na ciki, dyspepsia, ƙumburi da baki, ƙuƙwalwa, rash, nasopharyngitis, zawo, hanta aiki abnormalities, vomiting, ciwon kai, mashako, low platelet count, low number of white blood kwayoyin, kasawa da kowane nau'in jini, nau'i-nau'i, photosensitivity, da alopecia.
Idan kun fuskanci wani mummunan aiki ko mummunan dauki, za ku iya ba da rahoto ga FDA a http://www.fda.gov/medwatch/ ko ta kira 1-800-FDA-1088. Hakanan zaka iya tuntuɓar mai yin Otrexup a http://www.otrexup.com ko kuma kiran 1-855-Otrexup (1-855-687-3987).
Drug Interactions
Shan aspirin , NSAIDs , ko corticosteroids tare da Otrexup na iya tsawanta tsararren matakan da ke haifar da ƙara yawan guba. Samun proton pump inhibitors yayin amfani da Otrexup Har ila yau, zai iya ƙara da tsawanta serum methotrexate matakan, kara haɗarin rashin guba.
Tabbatar cewa likitanku yana da lissafi na yanzu na duk magunguna da kariyar da kake ɗauka. Haka kuma yana da kyau a yi amfani da kantin magani daya, idan za ta yiwu, don duk kwayoyi kwayoyi. Zai fi sauƙi don yin hulɗa da hulɗar magungunan likita idan dukkan kwayoyi ku ke cikin tsarin kwamfutar kantin da kuke zaɓar.
Gargaɗi da Tsaro
Akwai gargadi mai ban dariya ba tare da dangantaka da Otrexup wanda ya nuna cewa an kawo rahoton mai tsanani mai haɗari da mutuwa ba tare da yin amfani da hanya. Ana amfani da kwayoyi masu amfani da miyagun ƙwayoyi don yatsun kasusuwa, hanta, huhu, fata, da kuma koda koda. An kuma bayar da rahoto cewa Methotrexate ya haifar da mutuwar tayi ko kuma rashin haɗari wanda shine dalilin da ya sa aka hana ta ciki.
Ƙararrakin tsananin maye gurbin ɓawon jini, anemia na aplastic, da kuma cututtuka gastrointestinal da aka ruwaito a marasa lafiya dauke NSAID yayin amfani da hanya. Haɗarin hawan, fibrosis, da kuma cirrhosis na iya faruwa bayan an yi amfani da hanzari tsawon lokaci. Hannun pneumonitis na iya faruwa a kowane lokaci har ma tare da ƙananan sashi na methotrexate. Diarrhea, ulcerative stomatitis, ciwon jini da ciwon ciki, da tsinkaye na ciki zai iya faruwa. Mai tsanani, mai yiwuwa mutuwa, halayen fata zai iya faruwa. Hanyoyin cututtuka mai yiwuwa na iya samun ci gaba.
Lymphoma non-Hodgkins da sauran ciwace-ciwacen da aka nakalto a cikin marasa lafiya da aka bi da su tare da low dose methotrexate. Ya kamata a lura cewa a lokuta inda m lymphoma ya ci gaba a lokacin lura da methotrexate, katse methotrexate ya isa ya sa regression na lymphoma.
Methotrexate kuma a gwargwadon rahoto ya haifar da rashin haihuwa a wasu marasa lafiya, ƙananan ƙwayoyin cuta da kuma rashin daidaituwa. Wannan yana iya zama matsala yayin da ake amfani da matakai kuma na tsawon lokaci bayan an tsaya.
Kalma Daga
Mutane da ke amfani da Otrexup ya kamata suyi gwaje-gwajen jini na lokaci-lokaci ciki har da cikakkiyar ƙididdigar jini, hanta enzymes, da gwajin aikin aikin koda. Idan ana tsammanin al'amura na huhu, zane-zanen rayukan kirji da gwajin gwagwarmaya na iya zama dole.
Mutane da ke amfani da Otrexup ya kamata su fahimci abubuwa masu tasiri, don su iya ganewa da kuma bayar da rahoton al'amurra da zarar sun faru. Admittedly, lissafin abubuwan da ke faruwa mai ban tsoro shine abin ban tsoro, amma tuna, mutane da yawa suna amfani da hanya ba tare da fuskantar matsalolin ba. Sanin hankali da kulawa yana da muhimmanci.
Sources:
Otrexup. Cikakken Bayanan Bayani . Revised 3/2016.
Tarihin Amincewa na Otrexup. Drugs.com.