Shin ƙwararren taurari mai tsananin gaske ne?
Harsashin Eosinophilic, wadda aka fi sani da fuka-fuka, ita ce mafi yawan yawan ƙwayar fuka da aka samo asali a cikin girma. An lasafta shi a matsayin maɗaukaki , wanda ke nufin cewa akwai yanayin kwayar cutar don allergies ya zama dalilin cutar. Sabanin sauran nau'ukan fuka, fosinophilic fuka yana da numfashi daga iska daga jikin ka har zuwa mafi ƙanƙara ƙwayar hankalin ka.
Kumburi daga fuka na eosinophilic yana faruwa ne a matsayin wani ɓangare na rashin lafiyar jiki ko tsari na rigakafi, wanda ke fito da wani jini mai tsabta wanda ake kira eosinophils . Lokacin da kake karuwa a cikin kwayoyin jinin fararen jini, za ka sami yawan amsawar mai kumburi, wanda zai haifar da ɗaukar hanyoyi. Ruwa da ƙuduri da sakamakon zasu haifar da spasms a cikin hanyoyi (bronchioles) ku kuma haifar da alamar cututtukan fuka.
Tsarin jima'i
Asthma shine mummunan ƙwayar kullun da kake iya numfashi. Kimanin mutane 1 daga cikin 13 suna shan wahala daga wannan rashin lafiya na kullum kuma kusan rabin mutanen da ciwon sukari ke fama da cutar tarin fuka a kowace shekara. Sanin cewa mafi yawan waɗannan fitattun abubuwa ana iya hanawa idan ana kula da asiri. Yayinda aka yi tunanin cewa kwayar cutar guda ɗaya ce, ƙwayar fuka tana da ƙwararru da yawa waɗanda zasu iya canza yadda za a iya sarrafa fuka.
Kimanin mutum 1 daga cikin mutane 10 da ciwon sukari suna da ciwo mai tsanani.
Yayinda yawancin ciwon fuka da ƙwayar eosinophilic ba shi da sani ba, akwai wasu hasashe cewa kashi 50 zuwa 60 daga cikin 100 na cututtukan fuka mai tsanani a cikin tsofaffi na iya zama fukacin eosinophilic. Idan kun tsufa fiye da 35 lokacin da aka gano ku da ciwon ƙwayar ƙwayar cuta mai tsanani za ku sami haɗari mafi girma na kasancewa da aka gano tare da fosinophilic fuka.
Rashin haɗarinsa daidai ne ko da kuwa jinsi ɗinku, kuma ba ku da haɗarin samun ciwo tare da fosinophilic fuka a cikin yarinku da shekarunku.
Cutar cututtuka
Yawancin alamun bayyanar cututtuka na fosinophilic su ne kamar sauran fuka-fuka har da:
- Rawancin numfashi
- Coughing
- Wheezing
- Tightness a cikin kirji
Akwai wasu bayyanar cututtuka waɗanda na iya kasancewa ba a yawanci hade da fuka ba ciki har da:
- Rashin ruwa mai laushi da ruguwa ( rhinosinusitis na kullum )
- Nasal polyps
- Ƙara girman ƙwayoyin mucous
- Rashin haushi (anosmia)
Yayinda fukacin fosinophilic ba shi da wani maganin da ke da alaka da allergies, mutane da yawa da aka gano tare da shi basu sha wahala daga rashin lafiyar jiki irin su ƙwayoyi, mildews, ko sauran kayan jiki na jiki.
Sanin asali
An yi amfani da fuka mai azabar asibiti. Ba a yi la'akari da shi ba ko da yake an yi la'akari da yaduwa fiye da yadda aka yi imani.
Idan fushinophilic ƙwaro ne dalilin tarin fuka kuma ba a gano shi ba, za ka iya gwagwarmaya don samun ciwo mai tsanani a karkashin iko. Kullum kuna son ganin wani masanin ilmin likita idan kun damu. Duk da haka, masu haɗari da magungunan rigakafi na iya zama masu taimako a cikin kwarewarka.
Eosinophil Cell Count
Ana yin la'akari da ƙwayoyin eosinophils daga wani samfurin sputum wanda aka haifar shine la'akari da ma'auni na zinariya na ƙwayar ƙwayoyin ƙwayoyin cuta, amma yana da wuya a samu, cin lokaci, da kuma mai kula da hankali.
Ya sau da yawa yana buƙatar yin amfani da wani takamaiman lab ma'aikata tare da masana.
Yayin da aka tattara samfurin, kana so ka tabbatar da cewa baka dafa ba, sai dai kawu da tsutsa daga hanyoyi na iska. Don taimakawa wajen haifar da sputum, likitanku na iya samun magungunan kwantar da hankali na numfashi ya ba ku kashi na albuterol ko wani mai amfani da hanzari. Wannan magani ana biyo baya ta hanyar baka saline mai kyakken jini. Babban haɗuwa da salin yayin da inhaled ke shawo kan hanyoyi da kuma taimaka wajen haifar da tari. Za a iya nazarin samfurin samfurin samfurin a cikin wani lab din don ganin idan akwai fiye da 1 zuwa 3 daga 100 eosinophils.
Airway Biopsy
Wata hanya ta ƙayyade ƙuƙwalwar ƙwaƙwalwa ita ce ta dauki iska ta iska ta iska a lokacin da yake da ƙwayar cuta. Wannan hanya za a iya yi don kammala gwajin da yawa. Duk da haka, wannan hanya bata da shawarar kawai don gane fuka-fizin eosinophilic tun lokacin da yake da hanyar ɓarna da ke buƙatar ƙaddamarwa sai dai idan ba a samo samfurin sputum ba.
Wasu hanyoyi
An tsara wasu hanyoyi don taimakawa wajen bincikar e-fuka. Kwararka zai iya duba CBC (cikakken jini) don bincika eosinophilia (ƙara yawan ƙidaya eosinophil). Duk da haka, fassarar haɗarin eosinophils a cikin jinin ya kamata a yi shi kawai ta hanyar likita tun lokacin da aka ƙididdige shi a cikin jininka bazai tabbatar da cewa kana da fukaccen eosinophilic ba. Zai iya, duk da haka, taimaka wa likitanka don ƙara bambanta kowane irin bayyanar da kake ciki.
Wasu cututtukan da za a iya la'akari da su idan kuna da lamarin eosinophil wanda aka haɓaka a cikin jininku sun hada da ciwo na hypereosinophilic, ciwon kai tsaye, nakasar adrenal, da kuma halayen magani.
Ƙarin ƙarin gwaje-gwaje biyu za a iya ɗauka a matsayin mai haɗari zuwa gawar da aka samu ko kuma sanadin eosinophil jini: ƙwararren numfashi na nitric oxide (FeNO) da kuma gwajin jini na lokacin. Idan kana da ciwon fuka na eosinophilic, zaka nuna yawan ƙaramin eosinophils a cikin jininka da sputum, immunoglobulin E, FeNO, da kuma periostin.
FeNO zai iya zama da amfani wajen taimakawa wajen hango ko idan za ku amsa maganin corticosteroids. Za a iya gwada gwaji ta amfani da na'urar da aka kira NIOX. Duk da haka, dalilai masu yawa zasu iya rinjayar matakan ku na FeNO ciki har da yin amfani da steroids, shekaru, jima'i, haɗari (nauyin inganta ciwon allergies), da kuma shan taba.
Periostin shi ne mai halitta a cikin kwakwalwan kwakwalwar iska. Matakan periostin suna dauke da su a cikin asma wanda ke kunna wasu kwayoyin da ba a rigakafi (TH2) kuma a wasu nazari an nuna su zama kyakkyawan matsala don gwaji sputum. Duk da haka, sakamakon yana iya canzawa a wasu binciken kuma gwajin ba sauƙin samuwa. Gudun daji da ƙaddamar da jini eosinophil har yanzu sun fi dacewa ga FeNO da kuma periostin bisa ga yawancin likitoci da jagororin.
Jiyya
Yin amfani da asibiti na eosinophilic na farko zai hada da tsarin kula da asibiti na asali. Sau da yawa zaku sami sakamako masu kyau daga masu ciwon corticosteroids (ICS) waɗanda aka yi amfani da su a matsayin ɓangare na ka'idojin kula da asibiti. Duk da haka, idan likitan ku ya kamu da ku tare da fosinophilic fuka, za su iya canza tsarin da ake amfani dashi tare da corticosteroids. Corticosteroid magunguna sun hada da:
- QVAR (HAUSA mai cin gashin kansa)
- Pulmicort (budesonide)
- Ruwa (fluticasone proprionate)
- Asmanex (mometasone)
- Azmacort (triamcinolone acetonide)
Yayinda cikewar corticosteroids suna da sakamako masu amfani, wasu mutane suna da steroid-fractory eosinophilic fuka, wanda kawai yana nufin cewa ƙwayar fuka ba ta da alamar bayyanar cututtuka ko amfani na asibiti daga ciwon corticosteroids. Idan ka taya daya ko fiye daga cikin corticosteroids waɗanda aka lakafta a sama ba tare da taimako na alama ba, to, za ka so ka tattauna tare da likitan wasu daga cikin magungunan da suka samo kwanan nan don magance asibiti na eosinophilic.
Akwai hanyoyin magance cutar 3 da aka ba da izini wanda ya sami izinin FDA don rashin lafiyar asma:
- Xolair (omalizumab) wani maganin rigakafi ne na immunogobulin E (IgE)
- Nucala (mepolizumab), wanda aka fi sani da Bosatria, wani maganin maganin anti-interleukin-5 (IL5)
- Cinqair (reslizumab) wani maganin magani na IL5 ne
- Fasenra (benralizumab) shine sabuwar FDA ta amince da maganin IL5
Magunguna guda uku da aka lissafa a sama sun nuna sakamako mai dadi idan har yanzu har yanzu suna nuna alama duk da kyawawan dabi'un da aka tsara wa ka'idodin corticosteroid. Daga cikin magungunan nan guda uku, omalizumab yayi tsammanin kasancewa mafi nasara, yayin da yake rinjayar allergies fiye da mepolizumab da reslizumab. Wadannan magunguna kuma suna da kyau a jure su tare da ƙananan ƙananan sakamako tare da yiwuwar ku ma za su iya rage yawan amfanin ku na corticosteroids. Yin amfani da magungunan ƙwayar amfani da hankali yana haifar da raguwa a sakamakon da zai iya ƙara yawan rayuwarku.
Kulawa da Kulawa
Ana bada shawarar a biyo baya a matsayin maganin asibiti ba magani bane, amma magani. Yi shirye-shiryen gwajin lokaci kuma ka tattauna da wadannan likita tare da biyan kuɗi:
- Gwajin aikin gwaji
- Kwayoyin cututtuka da suka faru tun lokacin ziyarar da ta gabata (ingantawa ko kuma ciwo)
- Yawan mikiyukan fuka-fuka
- Nasarar rikitarwa kamar asarar wari
- Overall yanayin kiwon lafiya
- Binciken binciken binciken rayuwa mai kyau
- Laboratory bincike
Hanyar bin biyan kuɗi daidai ne game da watanni 4 bayan farawa farfadowa. Idan ka samu sakamako mai kyau, za a kiyaye ka a kan magani da aka tsara. Idan sakamakon bai da yawa zuwa matsakaici, to, za ku ci gaba da tayar da hankali a kan magani har tsawon shekara guda kafin yin la'akari da canzawa ko ƙara ƙarin magunguna. Idan ba ku da wata amsa bayan watanni hudu, to likita zai iya dakatar da magani kuma ya canza ku zuwa wani farfado da aka yi niyya.
Likitan likitanka na iya so ya bi matakan jini na IgE idan ya dauki komai. Duk da yake IgE matakan ba su gano asalin foshinophilic ba, wani maganin maganin warkewa ga omalizumab zai kasance ga ragewa a cikin yawan jinin IgE na jini.
Kalma Daga
Yayinda fushinophilic fuka yana hade da ciwon sukari mai tsanani, magani zai yiwu idan aka bincikar da yadda ya kamata. Rashin kuskuren ƙwayar fosinophilic zai haifar da wuya a sarrafa magungunan asthma wanda ba kawai ya kara yawan rayuwarka ba amma zai zama barazanar rai. Yin aiki tare da likitancin ku tare da maganin kwantar da hankalinku zai iya taimaka maka sake dawo da ingancin rayuwar da ka cancanci kuma zai iya rage yawan yawan haɓakar tarin fuka.
> Sources:
> Amfani na asibiti na Ƙarƙashin Ƙarƙashin Ƙarƙashin Ƙarƙashin Nitric Oxide (FeNO) a cikin Harkokin Asthma. Aikace-aikace don Nazarin Lafiya da Kyautattun Bayanan Yanar Gizo. Updated Dec 20, 2017. https://effectivehealthcare.ahrq.gov/topics/asthma-nitric-oxide/research/.
> Buhl, R, Humbert, M, Bjermer, L, Chanez, P, Heaney, LG. Holgate, S. (2017). Cikakken ehistoshinic asthma: wata hanya zuwa yarjejeniya. Turai na numfashi na numfashi. 49: 1700634, DOI: 10.1183 / 13993003.00634-2017.
> Asthma Eosinophilic. Abokan Hulɗa na Abokan Hulɗa na Yanar Gizo Eosinophilic. http://apfed.org/about-ead/eosinophilic-asthma. Updated 12/19/2017.
> Asthma Dat kwanan nan. Cibiyoyin Kula da Cututtuka da Cututtuka. http://www.cdc.gov/asthma/most_recent_data.htm. Updated 6/2017.
> Wagener AH, de Nijs SB, Lutter R, et al. Tabbataccen waje na eosinophils na jini, FE (NO) da kuma serum periostin a matsayin surrogates ga sputum eosinophils a cikin asma. Thorax 2015; 70: 115
> Walford, HH & Doherty, TA. (2014). Binciken da kuma gudanar da asibiti na eosinophilic: hangen zaman gaba na Amurka. J Allergy Asthma. 7: 53-65, misali: 10.2147 / JAAS39119.