Gwaje-gwaje-gwaje na Cutar Gashin Lafiya Aikin Rashin Magunguna na Rheumatoid
Akwai wasu gwaje-gwaje na jini da likitoci sukan umurta don tantance kumburi da kuma taimakawa wajen bincikar cututtuka. Kwanan gwaje-gwaje na jini guda hudu da aka yi akan marasa lafiya da ake zargi da samun ciwon maganin ƙwayar cuta , ko kuma don saka idanu akan tasirin magani, sun hada da rashawa na erythrocyte , CRP , factor rheumatoid , da anti-CCP . Amma, akwai 'yar jariri "sabon" a kan toshe, mai magana da ma'ana, da ake kira Vectra DA.
Vectra DA, wanda Cibiyar Cioscendo Bioscience ta kirkiro, ta zama gwajin kwayar halitta mai yawa don nazarin cutar cututtukan cututtuka a cikin marasa lafiya da aka bi da DMARDs (maganin maganin cututtuka da maganin cututtuka) da kuma maganin kwayoyi . Vectra DA ta haɗu da wani ɓangare na sunadarai masu mahimmanci 12 waɗanda aka hade da cutar arthritis a cikin gwajin daya wanda ya haifar da wani abu mai mahimmanci wanda ya shafi aikin cutar. Sakamakon, 0-100 (ƙananan kashi yana nuna ƙananan aikin cututtuka), yana taimaka wa likitoci da marasa lafiya suyi shawarar yanke shawara yayin da suke ci gaba.
Vectra DA an fara gabatarwa a ƙarshen shekara ta 2010. Tun daga nan, bisa ga Crescendo Bioscience, masu rheumatologists sunyi amfani da bayanan da kayan aiki zasu iya ba don magance cututtukan cututtuka a cikin mutanen da ke dauke da ciwon sukari. Vectra DA yana samuwa a cikin jihohi 50, kuma ana gwada gwajin a Crescendo Bioscience na Clinical Laboratory Improvement Amendments (CLIA).
Bayan an karbi samfurin jini kuma an gwada, ana bayar da rahoton a cikin kwanaki 7 zuwa 10. Doctors iya karɓar sakamakon a cikin wasu hanyoyi daban-daban: mail gidan waya, fax, ko a kan tashar yanar gizo portal Vectra View.
Bincika tare da mai zaman kansa mai insurer don tabbatar da cewa inshora ya rufe shi da Vectra DA. Medicare cikakken ɗaukar hoto na Vectra DA ba tare da takaddama ba ko kuma wanda ba zai iya ba.
Crescendo Bioscience yana so ya tabbatar da cewa kudin ba wani abu ne da zai iya hana kowa wanda ke dauke da ciwon wariyar launin fata wanda ya kamata yayi gwajin. Kuna iya kira 1-877-RHEUMDX (1-877-743-8639) don koyi game da taimakon kudi.
12 Biomarkers a Vectra DA
Wani mai tantance halitta shine kwayoyin a cikin jiki wanda za'a iya aunawa kuma an kimanta shi. An yi amfani dashi don ƙayyade al'amuran al'ada ko magungunan cututtuka, ko tasirin magani.
VCAM-1 (kwayoyin halitta mai ƙwayar jikin jiki-1) yana taka muhimmiyar rawa a cikin hulɗar tsakanin kwayoyin halitta, da jini, da kuma kayan haɗin kai a cikin haɗin gwiwa. A cikin kwakwalwan da kwayoyin rheumatoid ke ciki, hulɗar zasu iya taimakawa wajen gina jikin kumburi.
EGF (factor epidermal growth factor) an samar da kwayoyin halitta a cikin haɗin gwiwa wanda cutar ta shafa ta shafa, ta inganta ci gaban kwayoyin halitta da kuma kumburi.
VEGF-A (magungunan ƙwayar cuta mai cike da ƙwayar cuta) wanda aka haifar a cikin ɗakunan da aka flamed, yana taimakawa wajen samar da jini, ginawa da ruwa, da kuma yashwa na kashi.
IL-6 (interleukin 6) yana ɗauke da kumburi, tarin fuka-fuka, da kuma yaduwa na hakar da ke hade da cutar arthritis.
TNF-RI (magungunan ƙwayoyin ƙwayoyin necrosis na tumo, nau'in 1) mai karbi ne ga TNF-alpha, wani kwayoyin da ke motsa ƙonewa da haɗuwa.
MMP-1 (matrix metalloproteinase-1 ko collagenase-1) wani enzyme ne wanda ke taimakawa wajen lalacewa a cikin rheumatoid arthritis.
MMP-3 (matrix metalloproteinase-3 ko stromelysin-1) wani enzyme ne wanda ke lalatar da sassan sassa na guringuntsi.
YKL-40 wani sunadaran da ke taimakawa wajen tsara kayan gyaran nama da halakarwa.
Leptin wani hormone ne wanda kitsen jiki ya ɓoye, kwayoyin halitta a cikin haɗin gwiwa, da kashi. Leptin yana taimakawa wajen ƙonewa kuma yana tsara gyaran kashi.
Tsayayyar shi ne hormone ɓoyewa daga kwayoyin jikinsu a cikin haɗin gwiwa da kashi wanda ke taimakawa kumburi da kuma sarrafa kashi ta sake gyarawa.
SAA (magani amyloid) shine gina jiki wanda hanta ke haifarwa don mayar da kumburi.
Za a iya samar da amyloid mai magani ta hanyar haɗin gwiwa kuma, inda zai iya kunna nama da kuma maye gurbin sassan.
CRP (C-reactive gina jiki) ana haifar da hanta a mayar da martani ga kumburi.
Abin da Ma'anarka yake nufi
Harshen fassarar ku yana da mahimmanci: 45 zuwa 100 na nuna wani babban mataki na aikin cutar; 30 zuwa 44 na nuna aikin rashin lafiya; kuma 1 zuwa 29 na nuna ƙananan yanayin aikin cutar.
Layin Ƙasa
Vectra DA gwajin yana dacewa ga marasa lafiya da aka riga an bincikar su da cututtuka na rheumatoid wanda, a buƙatar likitan su, za i suyi la'akari da matakin aikin cutar. Ba'a amfani dashi don gano asali ba. Yana kimanta aikin rashin lafiya.
A shekara ta 2016 EULAR (Turai League against Rheumatism) taron shekara-shekara, an gabatar da binciken binciken wanda ya nuna, baya ga maganin cutar cuta, Vectra DA iya "hango hangen nesa da cigaba remission a marasa lafiya dakatar da magani, da kuma magani amsa ga biologic kuma ba -rapilologics. "
> Sources:
> Vectra DA. Gwajin Ayyukan Cututtuka.
> Crescendo Bioscience ya sanar da cewa sabon bayanai akan Vectra DA ba za a gabatar ba a Turai game da Rheumatism 17th Congress Congress. Crescendo Bioscience. Yuni 10, 2016.