T-Cell Cuticular Lymphoma (CTCL) wani lymphoma ne na fata. CTCL taso ne daga T-cell , irin lymphocyte ko jini mai tsabta. CTCL ba wata cuta bane, amma ƙungiyar daban-daban na lymphomas da suka shafi fata da suka hada da:
- Mycosis fungoides,
- Sezary ciwo,
- Siccoma siccoma cell na fata, kuma
- Yawan sauran lymphomas.
Lymphoma ya ƙunshi lambobin lymph .
Duk da haka, kwayoyin lymph ko lymphocytes suna cikin dukkan jikin jiki. Fatar jiki abu ne mai mahimmanci na karewa don tsarin rigakafi, kuma wasu kwayoyin T suna ta ƙaura zuwa fata don karewa daga kamuwa da cuta. Kwayoyin ciwon daji na T-cell lymphoma kuma sunyi ƙaura zuwa fata. Yawancin siffofin CTCL suna da alaƙa da raunuka, ko raunin da suka faru, suna samar da fata.
Tashin kwayar T-cell cutane yana wakiltar ƙungiyar marasa amfani na Non-Hodgkin Lymphoma (NHL). CTCL asusun don kawai game da 1 a cikin 40 sababbin diagnostiza marasa lafiya NHL.
Dalili na Hadarin
CTCL yana shafar maza fiye da mata. Kowane mutum tare da CTCL yawanci a cikin shekaru hamsin ko sittin. Yara ba su da alaka sosai. An sami karuwa mai yawa a cikin yawan mutanen da ke fama da fata lymphoma a cikin shekaru 3 da suka gabata.
Ba a san yawancin game da hanyar CTCL ba. Sabanin wasu nau'o'in lymphomas, babu wata dangantaka da ƙwayoyin da aka sani.
Binciken bincike yana gudana don sanin abin da ke haifar da CTCL.
Cutar cututtuka
Na farko bayyanar cututtuka na fata lymphoma sun hada da bushe ko scaly fata, jan rashes, da kuma itching. Rashes sun fi kowa a cikin yankunan da aka rufe da tufafi. Wasu mutane na iya fara lura da ja ko duhu cikin fata. Wadannan bayyanar cututtuka ba ƙayyadadden kwayoyin lymphoma ba ne kuma yawancin mutane ana kulawa da su saboda yanayin sanannen fata kafin a yi la'akari da lymphoma.
Yayin da cutar ta ci gaba, za a iya karfin ja, Ana ganin waɗannan alamomi kamar layi. Plaques na iya juyawa baya zuwa ƙwayoyin cuta ko ƙwayoyin cuta. A cikin ciwon da ke ci gaba, ulcers zai iya ci gaba a kan wadannan raunuka. CTCL na iya shimfidawa zuwa ƙwayoyin lymph ko sauran gabobin. Yawancin mutane tare da CTCL kawai suna da fata bayyanar cututtuka. Kimanin kashi 10 cikin dari na ci gaba na ci gaba da ci gaba da ci gaba da matsalolin matsala.
Sanin asali
Ana buƙatar saɓin fata don tantance CTCL. Za a bincika samfurin biopsy a karkashin wani microscope don gano kwayoyin lymphoma. Akwai wasu gwaje-gwajen da suka hada da gwaje-gwaje don alamun lymphoma (immunohistochemistry) da kuma kwayoyin lymphoma don neman irin lymphoma. Za a iya gwada CT ko wasu gwaje-gwajen hotunan don gano irin cutar.
Jiyya
Jiyya na fata lymphoma ya bambanta da yadda ake bi da sauran lymphomas. Tsarin dabarun ku zai dogara ne akan yadda aka sanya fata, irin launi na fata, da kuma sanya hannuwan jikin ko wasu jikin jiki.
Ana amfani da nau'ikan magani iri-iri:
- Magunguna na kariya sune kan fata
- Kwancen fata na farar fata - nau'in radiation treatment
- Psoralen da ultraviolet A haskoki
- Ultraviolet B haskoki
- Bexarotene - duka a matsayin gel da Allunan
- Denileukin Difitox
- Interferon alpha
- Chemotherapy da injections ko kwayoyi
Kusan kwanan nan, Cibiyar Abincin Amurka da Drug Administration (FDA) ta amince da gwanin mechlorethamine (Valchlor) a kan yadda ake kula da fata na mycosis fungoides, mafi yawan al'amuran CTCL. Kafin ta amince da shi, an yarda da mechlorethamine kawai don maganin cutar.
Kalma daga
Wata kungiya ta masana'antu ta Turai ta sadu da kuma wallafa shawarwarin su game da maganin daban-daban da kuma lokuta na CTCL, suna lura da cewa maganin cututtukan fata har yanzu shine mafi dacewa don dacewa da tsaka-tsakin mycosis, kuma mafi yawan marasa lafiya da masu launi na mycosis suna iya dubawa. sa ido ga rayuwa ta rayuwa.
Abin takaici, ƙwarewar ba ta da kyau ga marasa lafiya da cutar ci gaba, sun lura, kodayake ga marasa lafiya marasa lafiya, za a iya samun rayuwarsu ta tsawon lokaci tare da ƙwayar allogeneic cell transplantation (alloSCT).
Duk da haka, an samu ci gaban ci gaba a cikin shekaru goma da suka gabata game da fahimtar irin yadda mai yaduwar cutar Mycosis da kuma Sezary na ciwo, saboda haka akwai begen cewa wannan zai haifar da ci gaba.
> Sources:
> Mai fassara F, Eder J, Assaf C, et al. Ƙungiyar Turai don Bincike da Kula da Ciwon Cutar AIDS don magance cututtuka na mycosis / Ciwo na Sezary - Sabuntawa 2017. Eur J Cancer. 2017; 77: 57-74.