Magungunan jini mai yawa ne gaskiyar rayuwa ga wasu marasa lafiya da cutar sankarar bargo, lymphoma da myeloma. Ana amfani da karfin jini don inganta yawan ƙwayoyin jini kuma su bi da alamomin da alamun alamun anemia - kamar gajiya, tunani mai hankali, rashin ƙarfi na numfashi da rauni . Duk da haka, yawancin jini na tsawon lokaci zai iya haifar da karfin baƙin ƙarfe - yanayin da, idan ba a rage shi ba, zai iya lalata zuciya da hanta.
Ta yaya Yake faruwa?
Iron yana da muhimmiyar rawa a jikinmu. Yana taka rawar a cikin matakai masu yawa, ciki har da kira DNA a yayin da sassan ke raba, da kuma kawo iskar oxygen daga huhu zuwa jikinmu da kyallen. Iron da muke dauka ta hanyar abincinmu yana danganta ga gina jiki wanda ake kira transrin kuma yana zagaye a cikin jini na jini.
A mafi yawancin, ana amfani da wannan ƙarfe don ya haifar da haemoglobin, abu a cikin kwayoyin jinin jini wanda ke dauke da iskar oxygen da muke numfashi cikin kyallen mu . An ajiye baƙin ƙarfe a cikin hanta, don amfani da shi a nan gaba.
Jigon jikin mutum ba shi da ikon iya cire koɗaɗa baƙin ƙarfe, ko da yake an yi amfani da baƙin ƙarfe a cikin tsarin al'ada kamar zubar da fata. Da zarar karfin ƙarfin ƙarfin ƙarfin jikin ƙarfin jikin ya isa, ƙarfe zai fara ginawa a wasu sassan jiki, wanda zai haifar da ƙarfe.
Sassarar jini na jini yana ba da ƙarfe mai yawa.
A cikin mutane masu lafiya, kimanin 1-2 mg na baƙin ƙarfe an juya a cikin rana da aka ba - wato, baƙin ƙarfe wanda aka karɓa daga abinci kuma ya rasa ta wurin zubar da fata da kuma kwayoyin gastrointestinal, alal misali. Ɗaya daga cikin ɓangaren kunshe da jinsin jinin jini (PRBCs), duk da haka, ya ƙunshi kusan 200-250mg . Mafi sau da yawa, marasa lafiya suna karɓar raka'a biyu a duk lokacin da aka canja su, don haka shine karin karin miliyon 500 a rana ɗaya.
Hanyoyin
Lokacin da baƙin ƙarfe ya rinjaye iyawar jiki don ajiye shi da aminci, zai iya haifar da lahani a hanyoyi da yawa. Da farko, idan akwai ƙarfe a cikin jiki fiye da canzawa don ɗaure shi, sai ya kewaya ta kusa da kansa a matsayin wanda ba a canza shi ba (NTBI). Wannan nau'i na baƙin ƙarfe ne mai guba ga jikinmu, kuma yana haddasa lalacewar jikinmu da gabobin a matakin salula.
Bugu da ƙari, ƙarfe mai yawa yana tarawa a cikin zuciya, huhu, kwakwalwa, endocrin gland, hanta kuma har ma da kasusuwa.
Untreated, wannan jari zai iya haifar da:
• Ƙarfin zuciya
• rashin amfani
• Ciwon sukari
• Cirrhosis na hanta
• Arthritis
• Hypothyroidism (underroiding thyroid)
• Ci gaba da rashin ƙarfi
• Dirfunction Erectile
• Ciwon daji
• Dama
Wasu shaidu kuma suna nuna cewa kamuwa da kwayar cuta na kwayar cutar na iya kasancewa daya daga cikin sakamakon sakamakon sauke ƙarfe.
Wane ne ke cikin Hadarin?
Mutanen da ke cikin haɗari na ƙwayar baƙin ƙarfe mai karfin jini sune wadanda suka karbi yawan jini na jini. Mazan da suke karbar karbar jini suna cikin haɗari bayan kimanin kashi 20 na raka'a na PRBCs, ko kuma sauyawa 10 idan ka sami raka'a biyu a lokaci guda.
Marasa cutar sankarar jini da lymphoma, irin su cutar sankarar bargo da lymphoma, yawanci suna buƙatar yawancin ƙwayar cutar bayan sunadarai, bayan radiotherapy zuwa yankin pelvic su, ko kuma biye da tsire-tsire na cell .
Magunguna da ƙwayoyin cuta na myelodysplastic (MDS) sau da yawa suna da rashin haemoglobin mai ci gaba kuma mutane da yawa suna dogara ne da jini, suna sa su a babban haɗari don sauke nauyin. MDS tare da maganin anemia na tsakiya zai iya haifar da marasa lafiya su karbi nauyin baƙin ƙarfe daga abincin su, yin matsalar har ma da muni.
Sanin asali
Sauye-sauyen ƙarfe yana faruwa a tsawon lokaci, kuma sau da yawa marasa lafiya ba za su nuna alamun ba. Zai fi yiwuwa cewa samfurin gwagwarmaya zai iya gano karfin ƙarfe a gaban mutum yana da alamun bayyanar.
Kwalejin da aka fi dacewa don gwada ƙarfin ƙarfin baƙin ƙarfe ana kiransa matakan ƙwayar jiki. Wannan gwajin jini ne wanda za'a iya yi akai-akai don mutane masu haɗari.
Rigarrun ƙwayar ƙwayar sukari ya karu kamar yadda yawancin NTBI ya karu cikin jinin. Tsarin gine-gine na jini wanda ya fi 1,000 mcg / L ya nuna nauyin ƙarfe. Mutane masu lafiya sun kasance suna da maganin serritin na 24-336 mcg / L da mata masu lafiya 12-307 mcg / L. Sauran cututtuka da yanayi na iya haifar da ƙwayar ferritin mai yawa don a saki a cikin wurare dabam dabam, duk da haka, wanda zai iya yin karatu guda ɗaya wanda ba shi da tabbacin, don haka gwadawa akai-akai shine al'ada.
Magungunan ƙila ma za su zaɓa su yi hawan kwayoyin hanta don duba ƙin baƙin ƙarfe. Duk da yake wannan gwaji na iya ba da cikakkun bayanai fiye da nauyin ƙwayar jiki, ya buƙaci hanya mai banƙyama wanda zai haifar da rikitarwa, kamar kamuwa da cuta da zub da jini. Sakamakon kwayoyin halittu mafi girma fiye da nau'i na 7 MG da nau'in hanta ya nuna nauyin ƙarfe.
Nazarin ilmantarwa zai iya bayyana abubuwan da suke nunawa game da ƙarfe. Za'a iya amfani da hotunan haɓaka na Magnetic (MRI) don gano ƙwayar ƙarfe a cikin hanta da kuma zuciya. Ana iya amfani da MRI tare da hawan mai ilimin hanta don tantance ƙarfin ƙarfe ko kuma kai tsaye. Duk da haka, ba a amince da MRI ba a wasu lokuta, irin su lokacin da ake yin baƙin ƙarfe a cikin pancreas.
Jiyya
Akwai hanyoyi guda biyu da aka yi amfani da nauyin ƙarfe a cikin ƙarfe: farfadowa da magungunan furotin da sauransu.
Harkokin ilimin lissafi shine hanyar da ta fi sauri da kuma mafi inganci don samun matakan ƙarfe a cikin mai haƙuri. Abin takaici, ba za a iya amfani dashi ba a kan marasa lafiya da suka kasance anemic. Sabili da haka, ana adana yawan marasa lafiya waɗanda cutar cutar sankarar jini ko lymphoma ke cikin remission.
A yayin da ake cike da cutar, likita ko likita za su saka babban allura a cikin ƙwaƙwalwarka , yawanci a hannunka. Sai su cire kimanin lita 500 na jini daga jikinka kimanin minti 15-30. Idan ka taba bayar da jini, zaka sami ra'ayin. Wannan adadin jini yana dauke da nau'in mita 250. Yayin da aka cire wannan ƙarfe ta wurin jininka, hanta zai sake wasu daga cikin kayan ajiyarsa kuma a ƙarshe ana iya mayar da adadin baƙin ƙarfe a cikin jeri na al'ada. Za a iya yin wani abu sau ɗaya ko sau biyu a mako kamar yadda ya cancanci don cimma burin kwayoyin ƙwayar ferritin na 50-100mcg / L.
Maganin iron chelation yana amfani da magunguna wanda ke ɗaure, ko chelate, baƙin ƙarfe da kuma sauƙin cire shi daga jiki. Manufar irin wannan farfasa ita ce kawar da baƙin ƙarfe daga jini da kwayoyin jikin. Kodayake wannan farfadowa yana aiki sosai a kan ƙwayar plasma da hanta da ƙwayoyin hanta, ba abu mai tasiri ba ne wajen cire kwalliyar baƙin ƙarfe daga zuciya.
Deferoxamine (Faɗakarwa), cutrasirox (Exjade), da deferiprone (Ferriprox) sune uku magunguna.
Magunguna masu magungunan iron din suna da tasiri wajen rage matakan NTBI, amma waɗannan matakan sunyi sauri idan an dakatar da farfadowa. Saboda haka, dole ne a ɗauki waɗannan magunguna daidai yadda aka umurce su suyi aiki yadda ya kamata. Wannan zai iya zama babban alhakin wasu marasa lafiya. Ma'aikata masu amfani da ƙura ba ma ba tare da cututtuka ba, kuma hadarin da kuma amfani da baƙin ƙarfe baƙin ciki ya kamata a yi la'akari sosai.
Bugu da ƙari da waɗannan maganin, mai bada sabis na kiwon lafiya zai iya yin shawarwari don rage yawan baƙin ƙarfe da ka sha ta wurin abincinka. Duk da yake wannan ma'auni ne wanda yake da hankali sosai, tare da wasu 'yan kaɗan, amfanin amfani da ƙin baƙin ƙarfe a cikin abinci yana da kwarewa tun lokacin da wannan matsala ta sha wahala daga maɓallin "gilashi a cikin guga", kuma tun lokacin da ake jiyya don ƙarfe baƙin ƙarfe irin su phlebotomy mafi tasiri a rage matakan ƙarfe.
Tips on Kai-Care
Cigar jini yana da mahimmanci da kuma tasiri na cutar sankarar bargo da magani na lymphoma. Abun cutar zai iya zama mummunar cutarwa, har ma da muni, illa a jikinka da kuma karfin jini na iya zama wanda ba a iya shakkuwa.
Duk da haka, akwai abubuwa da za ku iya yi domin tabbatar da ganin yadda matakan ƙarfinku suke kula da kyau. Tabbatar cewa kamfanonin kiwon lafiyarku na yanzu sun san duk labarin tarihin jinin jini na baya. Kila ka karbi PRBCs shekaru da suka wuce don yanayin da ba shi da dangantaka, amma likitanka ya kamata ya sani game da wannan yanzu. Ka tuna cewa baƙin ƙarfe ba shi da hanyar da za a cire daga jikinka, saboda haka kowace fassarar da kake karɓa a rayuwarka tana da damar bayar da gudummawa ga karfin ƙarfe a yau.
Ya kamata ku yi ƙoƙari ku ci gaba da lura da kowane fassarar da kuka karɓa. Wannan bazai da sauƙi, kuma akwai lokuta a farfadowarka lokacin da alama kamar duk abin da kake yi shi ne karɓa, amma zai zama mahimmanci a baya.
Kamfanin ku na kiwon lafiyar ya kamata ku fara nazarin kwayoyin halittarku na rukuni bayan kun sami kimanin tsawon shekaru 20 na jini. Idan kuna samun raka'a biyu a wani lokaci, wannan zai iya zama sau goma kawai. Idan ba su tsara ta atomatik ba, ya kamata ka nemi shi.
Layin Ƙasa
Marasa lafiya da ke karɓar jini na jini a cikin rayuwarsu suna fuskantar hadarin bunkasa ƙarfe. Saboda yanayin cututtukan su, kuma hanyoyin shan magani sunyi amfani da su, jinin da ciwon daji marasa lafiya ne sau da yawa transfusion-dogara ga wani lokaci. Idan ba tare da izini ba, ƙarfewar ƙarfe zai iya haifar da mummunan kwayoyin halitta da lalacewa, har ma da mutuwa, amma ana iya samun jiyya mai mahimmanci.
Duk da yake ba zai yiwu ba ne don guje wa karuwar jini, marasa lafiya zasu iya taimakawa wajen kare kansu ta wajen tunawa da yawan raka'a da suke karɓarwa kuma suna buƙatar gwaji idan aka buƙata.
Updated Maris 2016, TI.
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