Fahimtar Cachexia a marasa lafiya

by Lynne Eldridge, MD; Binciken by Grant Hughes, MD

Cutar cututtuka, da mahimmanci, da kuma maganin Ciwon Cutar Cancer

Cachexia wata cuta ne na kowa na ciwon daji (kuma wasu yanayi na kiwon lafiya kamar HIV / AIDs) wanda ake jin cewa yana da alhakin kashi 20 cikin 100 na mutuwar daji a Amurka . Wannan ya ce, ba a iya gano shi ba har sai ya kasance na tsawon lokaci. Menene ainihin cachexia, menene alamomi da alamomi, menene ya haifar, kuma yaya aka bi ta?

Bayani

Cachexia wani ciwo ne wanda ke nuna alamun rashin lafiyar rashin lafiya, rashin ciwo mai tsoka, da rashin ci. Kasancewa a akalla kashi 50 na mutanen da ke ciwon ciwon daji, an kiyasta cewa yana taimakawa kashi 20 cikin 100 na mutuwar daji .

Ko da yake ana nuna alamar bayyanar cututtuka da alamun cachexia a cikin marigayi na ciwon daji, muna koyo cewa tsarin da ke haifar da raunin tsoka yana farawa ne da wuri bayan bayan ganowar ciwon daji. A irin wannan, cachexia yakan kasance a gaban lokaci kafin wani asarar nauyi ya auku.

Ana amfani da cachexia a matsayin wani ciwo na paraneoplastic , wanda kawai yana nufin alamar cututtuka da ke haifar da abubuwa da ciwon daji ke haifarwa ko kuma yadda jiki yayi ga ciwon daji. Zai iya zama kamar cachexia ya kamata a sauƙaƙe shi a kallo na farko, amma jiyya yana da kyau. Wannan shi ne saboda cachexia ya fi kawai rashin rashin adadin kuzari a jiki.

Ƙungiyar tare da Ciwon Cutar

Ana ganin yawan cachexia akai-akai tare da ciwon daji amma ana ganinsa tare da cututtuka irin su AIDS / HIV, ciwon zuciya , emphysema , da kuma koda koda. Game da ciwon daji, ana ganin shi mafi yawanci tare da ciwon huhu na huhu , ciwon daji na pancreatic , da ciwon ciki.

Cachexia ba wai kawai cike da rayuwa ga mutanen da ke fama da ciwon daji ba, amma yana tsangwama da ingancin rayuwa.

Mutane da cachexia sun kasa iya jure wa jiyya, irin su chemotherapy , kuma sau da yawa suna da ƙarin illa. Ga wadanda suke da tiyata , matsalolin da suka shafi aiki ba su da yawa. Cachexia yana damuwa da gajiya na ciwon daji , daya daga cikin bayyanar cututtuka na ciwon daji.

Cutar cututtuka

Babban magunguna na cachexia sun haɗa da:

Abin da ba daidai ba (rashin kulawa) asarar nauyi: Asarar nauyi tare da cachexia yana da hannu, yana nufin cewa yana faruwa ba tare da ƙoƙari ba. Duk da haka ya wuce fiye da asarar rashin nauyi. Rashin hasara zai iya faruwa ko da yake kuna samun adadin adadin kuzari a cikin abincinku, kuma idan cin abincin calorie ya fi ƙarfin samar da makamashi.
Maƙarƙan ƙwaƙwalwar ƙwaƙwalwa yana raguwa: Ƙunƙarar ƙuƙwalwa shine alamar cachexia kuma yana faruwa tare da asarar mai. Hakanan zai iya zama mai banƙyama. A cikin mutanen da suke da karba a lokacin ganewarsu, asarar hasara na muscle zai iya faruwa ba tare da bayyanar bayyanar nauyin hasara ba.
Anorexia / asarar ci: Rashin ci abinci shine wata alama ce ta cachexia, kuma kuma, wannan alama ce ta bambanta da "asarar" ciyayi. Tare da cachexia, ba kawai ragewar buƙata ga abinci ba, amma mafi yawan hasara na sha'awar ci.
Ƙarƙashin rai mai kyau: Raƙƙarwar ƙuƙwalwa zai iya rage ikonka na tafiya da kuma shiga cikin ayyukan da za su kasance da farin ciki.

Dalilin

Ana iya haifar da cachexia ta hanyar "ƙwayoyin tumɓuke" - abubuwa da aka gina da kuma ɓoyewa da ƙari, ko kuma "amsawar mai karɓa." Amsar mai watsa shiri tana nufin ma'anar jikin ta zuwa tsari. An mayar da martani ga tsarin rigakafi don ciwon daji da sauran cacaxia don kokarin gwada abubuwan da ke cikin cachexia.

Cachexia ya mamaye metabolism na catabolic. Idan kuna tunanin al'ada al'ada ta hanyar gina jiki da ƙwayar tsohuwar jiki (na anabolic metabolism), akasin haka gaskiya ne tare da cachexia, wanda shine rashin ƙarfi na tsarin tafiyar jiki na al'ada.

Bincike

Akwai hanyoyi da dama da za'a iya kimanta cachexia.

Wasu daga cikin wadannan matakan sun hada da:

Rajista ta jiki (BMI): Rubutun launi na jiki ba wai kawai nauyin jiki ba ne amma zai iya ba da ƙarin bayani game da nauyin lafiya. BMI ana lasafta ta hanyar amfani da tsari na tsawo da nauyi.
Masarar kututture a jikin kututture: Sakamakon jikin jiki zai iya taimakawa wajen ƙayyade adadin ƙwayar tsofaffin muscle a jikin jiki. Gwaje-gwajen da aka yi amfani da wannan na iya haɗawa da launi na fata da kuma yadda aka yi amfani da su.
Abincin abincin abinci: Yin adadin abincin abinci yana da muhimmanci a yayin da kake kallo don hana ko magance cachexia. Bugu da kari, yana da muhimmanci a tuna cewa rashin abinci mai gina jiki na cachexia zai iya faruwa ko da tare da samar da adadin kuzari.
Gwajin jini: Wasu gwaji da ke amfani da su a kimantawa na cachexia sun haɗa da ƙididdigar jinin jini (WBC), serin albumin, matakan canja wuri, acid uric, da alamomin kumburi, irin su C-reactive protein (CRP) .

Jiyya

Hanyoyin da ake fuskanta a kwanan wata sun kasance da mummunan rauni, kuma har ma da adadin calories mai kyau, yana da wuya a soke tsarin cachexia. Manufar kulawa ita ce ta ƙarfafa "tsarin anabolic" (wato, ƙwayar tsohuwar) yayin da yake hana "aiwatarwa" (ayyukan da zai haifar da raunin tsoka). Jiyya na iya haɗa da:

Abincin abinci: Ba daidai ba ga abin da zai iya bayyana, maye gurbin da kuma ƙara yawan calories a cikin abincin ba ya haifar da babbar bambanci a cikin ciwon cachexia ba. Wannan ya ce, yana da mahimmanci a tabbatar da cewa mutane suna fama da ciwon daji (da kuma irin wannan yanayi da ke haifar da cachexia) suna da abinci mai kyau. Abu daya mahimmanci shine mu tuna cewa idan wani bai ci abinci ba har tsawon lokaci, ya kamata a kara yawan abincin. Idan calories suna matsawa da sauri, wani sakamako mai tasiri da ake kira "ciwon ƙwayar cuta" zai iya faruwa. Lokacin da cin abinci ba zai yiwu ba (ko an iyakance shi) a cikin magana, za'a iya bada tayin mai kwakwalwa .
Abubuwan da ake ginawa na gina jiki : Yana da manufa idan an samo kayan abinci ta hanyar abinci, amma mun san cewa ba haka ba ne. An kiyasta man fetur don iya iya kula da cachexia tare da wasu nazarin (amma ba duka) yana cewa zai iya taimakawa ba. A cikin nazarin daya, ƙara kariyar foda na eicosapentaenoic acid (EPA) , daya daga cikin manyan albarkatun mai uku-omega-3 wanda mutane suke samun abincin su ta hanyar cin kifi, inganta yanayin alamun alamomin kumburi wanda ke tafiya tare da cachexia. Har ila yau, an ha] a da magungunan EPA tare da raguwar asibiti da kuma rashin ciwo da damuwa.
Motsa jiki: Yana iya zama abin ƙyama, amma kara aiki (idan zai yiwu) zai iya taimakawa. Ayyukan motsa jiki na hakika yana ci gaba da ci, amma ƙarfafawa na iya ƙetare halayyar cin abinci don taimakawa jinkirin raguwar muscle da aka gani tare da cachexia.
Magunguna: Da dama magunguna da kari da aka yi kokarin cachexia tare da nasarar da aka iyakance sun haɗa da:
- Megace (megestrol)
- Thalidomide
- Zyloprim (allopurinol)
- Celebrex (celecoxib)
- L-Carnitine
- Medroxyprogesterone
- Testosterone
- Magunguna da Marinol

Future of Cachexia Jiyya

Da dama magunguna suna a cikin gwaje-gwaje na asibiti waɗanda ke nuna alƙawari a taimaka wa mutane su magance alamun da ke cikin cachexia. Wasu daga cikin waɗannan sun kasance a cikin gwaje-gwaje na uku - gwajin gwaji wanda yayi la'akari da miyagun ƙwayoyi ko hanyar da aka rigaya an yi la'akari da aminci da tasiri. A halin yanzu, da kuma cewa gaskiyar cewa cachexia yakan fara tun kafin ya bayyana a jarrabawar jiki, yana da muhimmanci a magance wannan rikitarwa ga mutane da yanayin irin su ciwon daji na huhu a wuri-wuri bayan ganewar asali.

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Bayani

Ƙungiyar tare da Ciwon Cutar

Cutar cututtuka

Dalilin

Bincike

Jiyya

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