Sashin ciwon mawuyacin hali shine cutar jini wanda ke shafar sassan jiki kuma yana haifar da alamun bayyanar. Yana shafi maza da mata kuma yakan fara bayan shekaru 50, ko da yake yana iya faruwa a kowane zamani. Ba'a san yadda sau da yawa yawan ciwo na POEMS ya faru saboda yana da wuyar ganewa daidai. Ba'a san dalilin ba.
Cutar cututtuka
Aroncin labaran POEMS yana tsaye ne:
- P - polyneuropathy, ma'ana jijiya bayyanar cututtuka irin su numbness, tingling, da / ko rauni na hannun hannu da ƙafa
- O - genomegaly, ma'anar kara girma gabobin, yawanci hanta, yada, ko kuma lymph nodes. Kimanin kashi 15 cikin dari na mutanen da ke fama da ciwo na POEMS suna fama da cutar Cristal (ƙwayar ƙumburi na lymph).
- E - endocrinopathy, ma'ana canje-canje na samar da hormone. Kwayoyin cututtuka irin su ciwon sukari , rashin ƙarfi , tsayar da hankalin mutum ( amenorrhea ), ƙananan ƙwayar thyroid (hypothyroidism), da / ko ci gaban nono a maza (gynecomastia) na iya kasancewa.
- M - monoclonal gammopathy ko ƙwayar cutar ƙwayar cutar plasma monoclonal, duka biyu ma'anar ma'anar jini sunadaran jini
- S - canza launin fata kamar ƙara ƙwayar fata (hyperpigmentation); ƙãra jiki gashi (hypertrichosis) a kan fuskar, limbs, da kirji; fata thickening da tightening, busa (edema) na kafafu da ƙafa, girke da kusoshi.
Kowane mutum na iya shawowa, gajiya, ƙuntatawa da ciwo, ko canje-canje a hangen nesa, tare da sauran alamun bayyanar.
Sanin asali
Za a iya gane asali na ciwo na POEMS bisa ga binciken lafiyar mutum da kuma tarihin likita. Anyi gwaje-gwajen jini kamar surar ƙwayar jinin jini (CBC) da kuma tsarin gina jiki mai gina jiki wanda aka yi domin neman abubuwan da ba su da mawuyacin hali, kamar yadda jarrabawa take. Matakan karamar thyroid, matakan glucose na jini, da kuma siffar estrogen a cikin jini ana gwada su don gane abubuwan da ba su da kyau.
Zai yiwu a yi amfani da rawanin kasusuwan maniyyi da / ko rasha-kashi don taimakawa wajen ganewar asali.
Ana ganin mutum yana da ciwon POEMS idan "P" (polyneuropathy) da "M" (magungunan jini sunadarai) suna tare tare da raunuka kashi ko cutar Ebola. Mutane da yawa za su sami wasu alamu na ciwo. Saboda yawancin likitoci ba su da masaniya game da rashin lafiya na POEMS, sakamakon binciken gwajin jini na yau da kullum yakan haifar da rashin fahimta na myeloma mai yawa, ko bayyanar cututtuka na polyneuropathy ya haifar da rashin fahimtar cutar ƙwayar cutar ƙwayar cuta (CIDP).
Jiyya
Yin jiyya na ciwo na POEMS ya dogara ne akan maganin cutar ƙwayar jini. Mafi yawancin mutane suna samun haɗuwa da jiyya irin su:
- Radiation far
- Corticosteroid magunguna kamar prednisone
- Chemotherapy
- Hanyoyin maye gurbin hormones waɗanda basu da yawa
- Jiki na jiki
- Bone marrow dashi
Kwararru irin su likitan ne (masanin tsarin likita), likitan jini (likitan jini), likitan jini (likitan fatar jiki), kuma masanin kimiyya (likitan kwalliyar wutsiyar hormone) sukan kasance a cikin kulawa da wani mutum tare da rashin lafiya na POEMS.
Sources:
Dispenzieri, Angela. "Ciwo na MUHS." Hematology 2005 (2005): 360-367.
Nasarawa, Angela, Robert A. Kyle, Martha Q. Lacy, S. Vincent Rajkumar, Terry M. Therneau, Dirk R. Larson, Philip R. Greipp, Thomas E. Witzig, Rita Basu, Guillermo A. Suarez, Rafael Fonseca, John A. Lust, & Morie A. Gertz. "Ciwo na POEMS: fassarori da kuma ƙarshen lokaci." Blood 101 (2003): 2496-2506.
"Hutun cututtuka na cutar ciwo na POEMS." Jiyya na Ciwo na POEMS a Mayo Clinic. Cibiyar Mayo. 22 Mayu 2007
Chan, Joanna, & Wingfield Rehmus. "Ciwo na MUHS." eMedicine. 15 Dec 2006. WebMD. 22 Mayu 2007