Inositol yana nuna alƙawari a matsayin mafita na farko ga dukan mata tare da PCOS saboda iyawarta na inganta sifofin rayuwa da haifuwa. Ga abin da zan sani.
Inositols su ne manzanni na sakandare
Rashin kamuwa da su kamar sunadarai da d-chiro inositol (DCI), sune mambobi ne na B-bitamin da kuma wani bangaren kwayar halitta. Inositol an samo shi a cikin abinci irin su 'ya'yan itatuwa , wake, hatsi, da kwayoyi da kuma jikin mutum.
Myo da DCI na aiki a matsayin manzannin sakandare da ke yada sakonni da ke cikin tsarin insulin. An yi imanin cewa matan da ke tare da PCOS na iya samun lahani cikin ƙarfin jiki don canza MYO a cikin DCI, don taimakawa ga haɓakar insulin da rashin haihuwa. Ƙarawa tare da inositol an dakatar da shi (babu wani sakamako irin na GI kamar metformin) kuma an nuna shi don inganta matakan insulin da kuma rage yawan sha'awar.
A Haɗin Myo da D-Chiro aiki mafi kyau
Binciken sabon binciken game da sakamakon inositol sun nuna cewa yawancin kyallen takalma cikin jiki suna da rabo daga myo zuwa DCI na 40: 1. Samun haɗin waɗannan abubuwa guda biyu da suka hada da wannan rukunin maimakon maimakon ɗauka kawai ko DCI kadai, an bada shawarar.
Idan aka kwatanta da myo inositol, haɗuwa da maganin na zuwa DCI sun nuna ƙarin amfani don inganta sigogi na rayuwa (rage yawan insulin, cholesterol, da alamomin ƙwayoyin ƙwayar cuta ) a cikin mata da PCOS.
Idan aka kwatanta da metformin , haɗin myo da DCI a cikin rabo na 40: 1 sun nuna kyakkyawan sakamako a gameda asarar nauyi, jima'i, da kuma hawan ciki (46.7 vs.11.2%).
Inositol Ratio Yana Shafan Tsarin Noma da Fari
Rashin daidaito a cikin jiki na tsarin jiki na myo zuwa tsarin DCI zai iya shafar kwai mai kyau. An nuna Myo inositol don inganta yawan kwai a cikin mata tare da PCOS yayin da ake amfani da DCI a manyan dogaye (600-2400 MG kowace rana) a cikin mummunan tasiri da kuma amsawa ta ovarian.
Mene ne mafi mahimmanci, kashi mafi girma daga DCI (kuma mafi girman girman MYO zuwa DCI), mafi muni da inganci da kuma amsawar ovarian.
Inositol na iya rage haɗari ga ciwon sukari
An nuna cewa matan da ke tare da PCOS na iya zama ƙari ga ƙwayar ciwon sukari (GDM) a ciki. Nazarin ya nuna cewa ƙarawa tare da myo inositol a cikin ciki yana da tasiri wajen rage hadarin ga GDM a cikin matan da ke da karba da kuma mata da PCOS. Wani binciken a cikin Gynecology Endocrinology ya nuna jigilar GDM tsakanin mata masu juna biyu tare da PCOS wadanda suka dauki ƙungiyar myo-inositol ya kasance 17.4% zuwa 54% a cikin rukuni.
Sources
Hamid A et al. Shafin Lafiya ta Mata na Shaida. 2015; 5 (3): 93-98.
D'Anna R1, Di Benedetto V, Rizzo P, Raffone E, Interdonato ML, Corrado F, Di Benedetto A. Myo-inositol na iya hana ciwon sukari na gestational a cikin matan PCOS. Gynecol Endocrinol. 2012 Jun; 28 (6): 440-2.
Costantino D, Minozzi G, Minozzi E, Guaraldi C. Hanyoyin maganin ƙwayar cuta da kuma hormonal myo-inositol a cikin mata da ciwon polycystic ovary: gwaji guda biyu. Europ review med pharmacol sci. 2009; 13 (2): 105-110.
Unfer V, Carlomagno G, Rizzo P, Raffone E, Roseff S. Myo-inositol maimakon D-chiro-inositol zai iya inganta darajar oda a cikin haɗarin inji na kwayoyin halitta. Mai yiwuwa, sarrafawa, gwajin gwagwarmaya. Europ review med pharmacol sci. 2011; 15 (4): 452-457.
Le Donne M, Alibrandi A, Giarrusso R, Monaco I, Muraca U. [Diet, metformin da inositol a cikin ƙananan mata da ƙananan mata tare da polycystic ovary ciwo: effects on jiki abun da ke ciki]. Minerva ginecologica. 2012; 64 (1): 23-29.
Rahoton R, Mocciaro R, De Trana E, D'Alessandro P, Morelli M, Zullo F. [Bincike na gyare-gyaren na asibiti, endocrinal da kuma bayanan masu kwakwalwa na marasa lafiya na PCOS da aka yi da myo-inositol]. Minerva ginecologica. 2012; 64 (3): 239-243.
Genazzani AD, Prati A, Santa Santa S, et al. Hanyoyin insulin daban-daban na maganin myo-inositol a cikin marasa lafiya na ƙwayoyin cuta na polycystic ovary. Gynecol Endocrinol. 2012; 28 (12): 969-973.
Gerli S, Papaleo E, Ferrari A, Di Renzo GC. Gyara, sau biyu gwajin gwagwarmayar makafi: tasirin myo-inositol akan aikin ovarian da abubuwan da ke cikin mata da PCOS. Europ rev da pharmacol sci. 2007; 11 (5): 347-354.
Raffone E, Rizzo P, Benedetto V. Insulin sanadiyar ma'aikata kadai kuma a cikin kulawa tare da R-FSH don shigarwa cikin mata a cikin matan PCOS. Gynecol Endocrinol. 2010; 26 (4): 275-280.
Galazis N, Galazi M, Atiomo W. d-Chiro-inositol da muhimmancinsa a cikin ciwo na polycystic ovary: nazari na yau da kullum. Gynecol Endocrinol. 2011; 27 (4): 256-62
Papaleo, E., Unfer, V., Baillargeon, JP, et al. (2007). Myo-inositol a cikin marasa lafiya tare da ciwo da cutar polycystic ovary: Hanyar da aka saba amfani da shi don yin amfani da ovulation. Gynecological Endrocrinology, 23 (12): 700-703.
D 'Anna R, Di Benedetto V, Rizzo P, et al. Myo-inositol zai iya hana ciwon sukari na gestational a cikin matan PCOS. Gynecol Endocrinol. 2012; 28 (6): 440-442.
Isabella R, Raffone E. Shin yara suna bukatar D-chiro-inositol? J Ovarian Res. 2012 Mayu 15; 5 (1): 14.
Dinicola S1, Chiu TT, Unfer V, Carlomagno G, Bizzarri M. Ma'anar maganin myo-inositol da D-chiro-inositol sun hada da maganin cutar polycystic ovary. J Clin Pharmacol. 2014 Oktoba; 54 (10): 1079-92.
Nordio M, Proietti E. Aiki tare tare da myo-inositol da D-chiro-inositol rage hadarin cutar rashin lafiya a cikin marasa lafiya na PCOS idan aka kwatanta da su na myo-inositol kadai. Eur Rev Med Pharmacol Sci. 2012 Mayu, 16 (5): 575-81.
Colazingari S, Treglia M, Najjar R, Bevilacqua A. Cikin maganin myo-inositol tare da D-chiro-inositol, maimakon D-chiro-inositol, yana iya inganta sakamakon IVF: sakamakon daga gwajin gwagwarmaya. Arch Gynecol Obstet. 2013 Dec, 288 (6): 1405-11.