Bincike ya nuna cewa akwai haɗin tsakanin nicotine da cututtukan cututtuka na huhu (IBD) . Duk da haka, abin da ke damuwa shi ne cewa shan taba yana da tasirin da ke faruwa a kan manyan nau'i biyu na IBD-ulcerative colitis da cutar Crohn.
Hanya tsakanin Tsakanin Ulcerative da shan taba
Binciken ulcerative colitis an fi mayar da ita a matsayin cuta na masu shan taba.
Tsofaffin masu shan taba suna cikin haɗari mafi girma don bunkasa ciwon ƙwayar cuta, yayin da masu shan taba na yanzu suna da ƙananan haɗari. Wannan hali yana nuna cewa shan taba sigari na iya hana farkon farawa na ƙin jini.
Masu bincike sun gano cewa shi ne nicotine a cikin cigaban cigaba wanda yana da tasiri mai kyau a kan alamun cututtuka na ulcerative colitis. Nicotine abu ne mai lahani a cikin taba wanda yana da tasiri mai mahimmanci a jikin kwayoyin da yawa da ke cikin jiki. Nicotine yana da nishaɗi sosai, kuma mutane da yawa da ke shan taba siga suna da matsala ƙetare duk da mummunan haɗarin kiwon lafiya.
An san cewa nicotine a cikin sigari yana rinjayar muscle mai tsabta a cikin sashin. Wannan tasiri zai iya canza maɓallin guttura (ƙimar da abincin abincin ya motsa ta hanyar GI).
Cutar Nicotine da Crohn
Shan taba taba yana da mummunar tasiri akan cutar Crohn. Mutanen da suke shan taba, ko kuma wadanda suka taba shan taba a baya, suna da mummunan haɗari na bunkasa cutar Crohn fiye da wadanda basu taba shan taba ba.
Kwayar Crohn marasa lafiya cewa hayaki yana da karuwar yawan sake dawowa da kuma sake magunguna kuma yana iya buƙatar magungunan immunosuppressive. Mutanen da ke da kwayar cutar Crohn suna karfafawa da karfi daga likitocin su daina dakatar da shan taba don hana ƙwayar cutar.
Kuskuren na biyu
Hawan hayaki a cikin yara yana da tasiri a kan hanyar IBD.
Yara da aka fallasa da hayaki na biyu sun rage hadarin cututtuka da kuma kara yawan haɗarin cutar Crohn.
Ya Kamata Tsofaffin Yau da Yau da Ƙungiyar Bincike Ta Yarda?
Wasu nazarin sun nuna cewa tsofaffin masu shan taba suna bunkasa ciwon ƙwayar cuta kuma sai su koma ga shan taba shan ƙananan alamu. Duk da haka, shan taba yana ɗauke da wasu ƙananan haɗarin kiwon lafiya. Magunguna ba za su ba da shawara cewa mai haƙuri zai fara shan taba ba, saboda hadarin shan taba ba ya wuce duk wani amfani da zai yiwu .
Menene Game da Dabbobi na Nicotine?
Yanzu ana iya samun alamun nicotine (wanda aka fi sani da nicotine transdermal) don shafewar shan taba, yana yiwuwa a nazarin sakamakon nicotine kadai ba tare da yada jiki ga sauran hadarin shan taba ba. Sakamakon magungunan ƙwayoyi suna nazarin yawancin kwayoyi a wani nau'in gwaji da aka sani da bincike mai kula da wuribo mai sau biyu. A cikin wannan nau'i na bincike, wasu marasa lafiya suna ba da sabon magani yayin da wasu aka ba da wani wuri mai dadi (placebo). Ba marasa lafiya ko likitocin da ke nazarin su sun san wanda ke karbar maganin miyagun ƙwayoyi kuma wanda yake samun wurin zama har sai an kammala karatun.
A cikin binciken biyu na makirci na makafi, an gano alamun nicotine mafi kyau fiye da placebo a wajen haifar da remission a cikin cututtukan ulcerative colitis.
Abin takaici, illa a cikin ƙungiyar nicotine sun kasance na kowa kuma sun haɗa da tashin zuciya, lightheadedness, da ciwon kai. Masu nazarin mahalarta wanda basu taɓa shan taba ba sun gano abin da ya faru na musamman musamman damuwa.
A wani binciken kuma, mutanen da ke da hagu na hagu da ke da hagu wanda basu da amsa ga magani tare da mesalamine na baki sun ba nicotine transdermal da mesalamine enemas. Wannan sabon hade yana da tasiri wajen haifar da gyarawa a cikin 12 daga cikin mahalarta 15.
Nicotine ba ya bayyana ya zama mai amfani a matsayin farfadowa na gyarawa; watakila ba zai taimaki marasa lafiya su tsaya a gafara ba. Maimakon haka, yana da wata tasiri mai kyau a kan cututtukan da ke fama da cutar ( wutan lantarki ).
Don hana haɓakar illa daga shinge, masu bincike suna tasowa hanyoyin da za su saki nicotine kai tsaye zuwa mazaunin. A cikin nazarin daya, an halicci matsule na nicotine don yin aiki a kan mallaka na tsawon sa'o'i 6.
Menene Wannan Ma'anar Ma'anar Mutum Tare da Ciwon Ulcerative Colitis?
Sakamakon sakamako na nicotine a kan cututtuka na ulcerative har yanzu ba a sani ba, amma yana nuna kyakkyawan shugabanci ga ci gaba da sababbin jiyya. Yayin da aka fahimci matsayi na nicotine akan mazaunin ya fi fahimta, marasa lafiya da ciwon cututtuka na iya samun wata rana daga sababbin jiyya bisa ga wannan sakamako.
Sources:
Green JT, Evans BK, Rhodes J, et al. "Tsarin maganganu na nicotine don saki da damuwa a cikin sashin: ci gabanta da pharmacokinetics." Br J Clin Pharmacol Oktoba 1999; 48: 485-493. 28 Mayu 2009.
Mahid SS, Minor KS, Stromberg AJ, Galandiuk S. "Shan taba a cikin yarinya yana da alaka da ci gaba da cututtukan zuciya." Inflamm Bowel Dis Apr 2007 13; 431-438. 28 Mayu 2009.
Pullan RD, Rhodes J, Ganesh S, et al. "Nicotine na Transdermal don ciwon cututtuka." N Engl J Med Mar 1994; 330: 811-815. 28 Mayu 2009.
WWW Sandborn, Tremaine WJ, Offord KP, et al. Transdermal nicotine don m zuwa moderately aiki ulcerative colitis. "An ba da izini, mai makafi guda biyu, jarrabawar wuribo." Ann Intern Med Mar 1997; 126: 364-371. 28 Mayu 2009.
Sandler RS, Sandler DP, McDonnell CW, Wurzelmann JI. "Yara da yara zuwa hayaki na taba taba da haɗari da haɗari da cututtuka." Am J Epidemiol Mar 1992; 135: 603-608. 28 Mayu 2009.