Endometriosis wani yanayi ne inda nau'in da ke tattare da ciki cikin mahaifa (endometrium) yana tsiro a wasu sassan jiki - yawanci a kan ovaries, tubes na fallopian, da sauran kwayoyin a cikin yankin pelvic. Zai iya haifar da ciwo da rashin zub da jini .
Endometriosis wata matsalar ce ta kowa, ta shafi kimanin kusan mata miliyan 5 da miliyan 5 na mata da mata na haihuwa.
Har ila yau cututtuka suna ganin sun ci gaba da muni fiye da lokacin ko lokacinka.
Babu magani ga endometriosis. Idan ba'a bi da shi ba, duk da haka, zai iya rage ka damar kasancewa cikin ciki a nan gaba. Endometriosis yana daya daga cikin manyan asali uku na rashin haihuwa. Makasudin maganin shine ya sarrafa ciwo kuma ya hana endometriosis daga ci gaba da muni. Jiyya na iya hada da magani da / ko tiyata. Irin magani wanda zaka iya nema ya dogara ne akan rashin lafiyar ka da kuma ko kana son zama ciki.
Depo-subQ Provera 104 shi ne allurar rigakafin da ke dauke da progestin, medroxyprogesterone acetate. An sami amincewar FDA a cikin watan Maris na 2005 don maganin ciwo na cututtukan endometriosis. Wannan amincewa ta FDA ya zama magunguna na farko don maganin jin zafi a cikin shekaru 15. Kodayake wannan amincewar FDA ba ta shafi ainihin Depo Provera shot, Depo Provera injections kuma zai iya taimakawa wajen magance ciwon da ke hade da endometriosis.
Yaya Depo Provera Zai Taimako Mutuwar Endometriosis?
Anyi amfani da progestin a cikin Depo Provera don taimakawa wajen rage ci gaban nama na nama da kuma iya rage ciwon ƙananan cututtuka na endometriosis.
Yayin da kake tafiya a cikin al'ada, jimmonanka na haifar da rufin mahaifa don yaduwa cikin shiri don ciki.
Idan ba kuyi ciki ba, rufin mahaɗin ku, kuma kuyi zub da jini (wannan shine abinda yake kawo lokacinku). Hanyoyin da ke kula da tsawan hankalinku na tasowa kuma sun fadi a duk tsawon lokacinku. Wannan tashi da fadowa zai iya haifar da bayyanar cututtuka don ƙara zama muni. Har ila yau, idan kuna da endometriosis, lokacin da kuke da lokacinku, zub da jini ba kawai yana fitowa daga jikin mahaifa ba - nama wanda ya ci gaba da waje a cikin mahaifa. Lokacin da wannan jini ya taɓa wasu kwayoyin halitta, zai iya haifar da ƙyama da ƙumburi wanda shine abin da ke ciwo.
Amfani da Depo Provera ya ba ka damar matakan hormone su kasance barga a cikin zagayowar ka. Yana taimakawa wajen zama mai ciki na cikin mahaifa - wannan zai iya haifar da lokaci mai haske ko a'a. Depo Provera na iya hana jirgin kwayar halitta kuma yana rage adadin isrogen wanda yake cikin jikinka. Manufar da ke nan ita ce, ƙasawan isrogen na ƙarfafa ƙwarƙashin endometriosis yana karɓo, ƙananan cell din yana faruwa. Wannan yana raguwa da girma daga cikin nama. Kamar dai yadda mahaɗin mahaifa ke amsawa ga waɗannan matakan hormone, adadin endometriosis yana da kyau.
Abin da sauran Magunguna ke bi Endometriosis?
Kafin amfani da maganin hormone (kamar Depo Provera) don maganin endometriosis, GnRH agonists (kamar leuprolide ) sun kasance magunguna da aka ba da umurni ga damuwa na endometriosis.
Wannan miyagun ƙwayar wani ɓangare ne na hormone na yanayi, wanda aka sani da hormone mai lausar gonadotropin, wanda ke taimakawa wajen sarrafa juyayi. Lokacin da kake amfani da leuprolide, yana daina dakatar da duk aikin hormone da aikin ovarian. Leuprolide yana hade da manyan halayen illa, wasu daga cikinsu sun hada da:
- Vasomotor bayyanar cututtuka (walƙiya mai zafi, sharaɗi, sweating)
- Rashin hasara
- Hanyoyin cututtukan hypoestrogenic (busassun ƙasa, saurin yanayi, damuwa cikin barci)
- Ciwon kai
- Dama
- Rage libido
Menene Bincike Na Magana game da Depo Provera vs. Leuprolide?
Ɗaya daga cikin sanannun bincike a wannan yanki idan aka kwatanta da Depo-subQ Provera 104 da kuma leuprolide amfani da mata 257 waɗanda aka gano da laparoscopically tare da endometriosis.
Akwai mata 153 da suka yi amfani da Depo-subQ Provera 104 da 146 matan da suka yi amfani da leuprolide a cikin watanni 6. Sakamakon ya nuna cewa:
- Depo-subQ Provera 104 yana da mahimmanci don magance ciwo ta hanyar endometriosis kamar leuprolide.
- Dukansu Depo-subQ Provera 104 da leuprolide amfani da kyau rage ciwo a cikin biyar main endometriosis bayyanar cututtuka: ciwo mai tsanani, dysmenorrhea , tausayi pelvic, dyspareunia (jima'i jima'i), da kuma induration (hardening da thickening na nama).
- Bayan watanni shida na amfani, Depo-subQ Provera 104 ya sa ya rage asarar ma'adinai na nama fiye da leuprolide. A cikin watanni 12 bayan shan magani, kashi-kashi na kashi ya koma magungunan pre-magani don masu amfani Depo-subQ Provera 104, amma ba ga wadanda suka yi amfani da leuprolide ba.
- Dukansu magungunan magunguna sun ba da gudummawa wajen bunkasa rayuwar rayuwa da kuma yawan yawan aiki.
Masu binciken sun kammala cewa Depo-subQ Provera 104 yana shawo kan cutar da endometriosis ya samu kamar yadda leuprolide ya samu. Amma mata da suka yi amfani da Depo-subQ Provera 104 sun bada rahoton alamun wutsiya (kamar walƙiya ko sutura) da kuma alamomin hypoestrogenic (kamar damuwa barci, sauyawa yanayi, da haushin hauka) kuma sun sami raguwar ƙananan ma'adinai fiye da mata da suka yi amfani da leuprolide. Saboda haka, ba wai kawai maganin hana haihuwa ba ne kawai , Depo-subQ Provera 104 yana da dacewa kuma yana da amfani a matsayin wani zaɓi na zafin jiki kamar yadda leuprolide ya yi don maganin ciwon rashin lafiya na endometriosis.
Ƙarin bincike kuma ya tabbatar da waɗannan sakamakon. A gaskiya ma, masu bincike sun sake nazarin binciken da suka binciko amfani da progestin don maganin endometriosis da aka buga a cikin shekaru goma (1993-2003). Hannun da aka samu daga dukkan waɗannan binciken sun nuna cewa kwayar medroxyprogesterone acetate, progestin a Depo Provera yana da tasiri kamar GnRH agonists (leuprolide) a rage rage ciwon endometriosis da kuma inganta lafiyar lafiyar rayuwa. Mawallafa sun kara bayyana cewa Depo Provera amfani da mata tare da bayyanar cututtuka endometriosis ya haifar da karuwa mai tsanani a cikin ciwo bayyanar cututtuka kuma ya haifar da raguwa a cikin sabon ci gaban endometriosis.
Depo Provera a matsayin Endometriosis Jiyya: Kalmar Magana
An yi amfani da Depo Provera don samun nasarar magance endometriosis. Babban mahimmancin tasirinsa shine Depo Provera na iya taimakawa wajen hana yaduwa . Depo Provera kai tsaye yana rinjayar nama ta jikin mutum ta hanyar haifar da shi ta bakin ciki - wannan yana haifar da ƙananan jini - wanda zai haifar da taimako mai zafi.
Duk da haka, Depo Provera na iya zama mafi mahimmancin magani ga endometriosis. Ko da yake yana da tasiri a cikin gajeren lokaci, bayan da ya dakatar da Depo Provera, akwai babban damar cewa ci gaba na nama zai dawo. Depo Provera kuma ba ya bi da rashin haihuwa da dangantaka da endometriosis. Idan kana son zama ciki, tiyata zai iya zama mafi kyawun magani don endometriosis.
Depo Provera yana da tasiri sosai kamar yadda leuprolide da sauran GnRH agonists ke magance matsalar ciwon endometriosis. Amma, leuprolide ya fi tsada kuma yana haɗuwa da ƙarin illa masu tasiri. Da aka faɗi haka, akwai Depo Provera tare da gargadi na kariya na akwatin baki - idan aka yi amfani da shi fiye da shekaru biyu, Depo Provera na iya ƙara ƙin ƙasusuwanku (wanda zai haifar da haɗarin osteoporosis ). Depo Provera amfani zai iya jinkirta dawowan amfanin ku (kimanin kashi 50 cikin dari na mata zasu iya yin ciki a cikin watanni 10 bayan karshen Depo Provera injection, amma zai iya ɗaukar watanni 18 don haihuwa don dawowa). Wasu mata suna bayar da zubar da jini ko kuma ci gaba da zub da jini lokacin amfani da Depo Provera tare da wasu abubuwan da ba'a so ba . Abin baƙin ciki, idan an ba ka da injin Depo, to, idan ba ka da damuwa da illa mai laushi, dole ne ka jira cikin watanni uku har sai dukkanin hormones daga wannan maganin ƙwaƙwalwa suna suma jikinka. Don haka idan kuna la'akari da amfani da Depo Provera a matsayin wani zaɓi na zafin ku don endometriosis, ku tabbata kuna magana da likitanku , don haka ku biyu za su iya ƙayyade ko bala'in da Depo Provera zai iya bayarwa ba ya wuce waɗannan hadarin.
Sources:
Crosignani PG, Luciano A, Ray A, da kuma Bergqvist A. "Dattijai na tsakiya wanda ke dauke da kwayar cutar acetate acupate acupate acupate acetate a maganin cututtukan cututtuka na endometriosis." Hum. Gyara. 2006; 21 (1): 248-256.
Vercellini P, Fedele L, Pietropaolo G, Frontino G, Somigliana E, da Corsignani PG. "Progestogens don endometriosis: Gabatar da baya." Hum Reprod Update 2003; 9: 387-396.