Lupus lura da tsare-tsaren tsare-tsaren suna dacewa da bukatun ku kuma zai iya canzawa a lokaci. Tsarin da tasirin jiyya ga lupus sun karu, suna ba likitoci mafi zabi a yadda za'a gudanar da cutar a kan ganewar asali da kuma bayan haka. Ana iya amfani da magungunan magani kamar kwayoyin immunosuppressive da anti-inflammatory, a tsakanin wasu zabin.
Yana da muhimmanci ku yi aiki tare da likitanku kuma ku taka muhimmiyar rawa wajen gudanar da cutar ku, ku sake nazarin shirinku na yau da kullum don tabbatar da lafiyar ku.
Da zarar an gano Lupus, likitanku zai inganta shirin yin magani akan ku bisa ga shekarunku, jima'i, kiwon lafiya, alamu, da kuma salon rayuwa. A cikin shirin bunkasa lafiyar ku, likitanku yana da nasarori da dama:
- Rage kumburi da cutar ta haifar
- Ƙarfafa ƙwayoyin cuta waɗanda suke da alhakin ƙumburi nama
- Yi haƙiƙa kuma ku bi da su lokacin da suke faruwa
- Control bayyanar cututtuka
- Rage raguwa
Sharuɗɗa
Magungunan magungunan magani sune muhimmin al'amari na kula da marasa lafiya da supsos lupus erythematosus (SLE), babban nau'in lupus. Za'a iya samar da tsararren likitanci a halin yanzu, wanda ya kara yawan yiwuwar magani mai mahimmanci da kyakkyawan sakamako masu haƙuri.
Lupus magani ya kamata ya haɗa da wasu magungunan ƙwayoyi kamar yadda ya kamata a matsayin ɗan gajeren lokaci ne sosai.
Wasu marasa lafiya basu buƙatar magunguna, wasu kuma suna ɗaukar su ne kawai idan ana buƙata ko don gajeren lokaci, amma mutane da yawa suna buƙatar mahimmancin farfadowa tare da maganin m. Duk da amfani, babu kwayoyi ba tare da hadari ba. Magunguna mafi yawancin amfani da su don sarrafa lupus bayyanar cututtuka sune:
- Magungunan anti-inflammatory marasa nau'in ƙwayoyin cuta (NSAIDs)
- Antimalarials
- Corticosteroids
- Immunosuppressives / cuta-gyaggyarawa anti-rheumatic kwayoyi (DMARDs)
Idan kana da bayyanar cututtukan lupus , za a iya bi da ku tare da antimalarial da yiwuwar NSAIDs da / ko gajeren lokaci na corticosteroids.
Idan kana da bayyanar cututtukan lupus , tsarin kulawa zai iya haɗawa da antimalarial tare da corticosteroid na dan kankanin har sai antimalarial ya yi tasiri. Kuna iya amfana daga immunosuppressive.
Don bayyanar cututtukan lupus mai tsanani wanda ya ƙunshi gabobinku, zaku iya buƙatar wani kashi mai mahimmanci na farfadowa na immunosuppressive. Za a iya bi da ku tare da babban allurai na corticosteroid don wani ɗan gajeren lokaci don rage ƙonewa. Kamar yadda mai laushi da tsaka-tsaka, za ku iya amfana daga antimalarial.
Zaɓuɓɓukan samfuran da za a iya samuwa da mahimmancin tsarin tsare-tsaren zai iya zamawa da damuwa. Da zarar likitanku ya zo da shirin magani, yana da mahimmanci ku fahimci dalilin da za ku yi amfani da miyagun ƙwayoyi, yadda yake aiki, yadda za ku dauka, lokacin da kuke buƙatar ɗaukar shi, da kuma abin da sakamakon illa mai yiwuwa zai iya zama. Idan baku da tabbacin, tabbas ku tambayi.
Yawancin marasa lafiya suna da kyau a kan magungunan lupus da kuma samun komai kaɗan.
Idan ka yi, ka yi kokarin kada ka karaya, ka tuna cewa ana amfani da magungunan ƙwayoyi. Har ila yau, sanar da likitanku nan da nan. Zai iya zama haɗari don dakatar da shan wasu magunguna, kuma kada ku daina dakatar da jiyya ba tare da fara magana da likitanku ba.
Antimalarials
Antimalarials an fara ne a lokacin yakin duniya na biyu domin quinine, maganin kula da cutar zazzabin cizon sauro, ba shi da cikakkiyar wadata. Masu bincike sun gano cewa antimalarials za'a iya amfani dashi don magance ciwon haɗin gwiwa da ke faruwa da cututtukan cututtuka na rheumatoid . Amfani na baya ya nuna cewa wadannan kwayoyi suna da tasiri a sarrafa waɗannan yanayin da ake lupus:
- Lupus arthritis
- Skin rashes
- Ciwon ciki
- Wulo
- Fever
- Kullu ƙonewa
Antimalarials, wanda Cibiyar Abinci da Drug ta Amurka (FDA) ta amince da ita don magance lupus, ana amfani dasu don taimakawa wajen kare mummunan lokacin da aka ci gaba da su, amma ba sa amfani da su wajen gudanar da tsarin launi da yawa wanda ya shafi gabobin. Zai yiwu makonni ko watanni kafin ka lura cewa wadannan kwayoyi suna sarrafa cutar bayyanar cututtuka.
Irin antimalarials sun hada da:
- Plaquenil (hydroxychloroquine sulfate)
- Aralen (chloroquine)
Ko da yake chloroquine har yanzu ana amfani dashi, saboda mafi aminci, hydroxychloroquine sulfate yawanci fĩfĩta. Ba a fahimci maganin ƙin ƙananan ƙwayoyin cutar ba. Antimalarials kuma yana shafar kayan abincinku don rage hadarin jini da ƙananan ƙwayoyin plasma.
Sakamakon sakamakon antimalarials na iya hada da:
- Dama tada
- Damage ga raina na ido (rare)
NSAIDs
Magungunan anti-inflammatory marasa lafiya (NSAIDs) suna dauke da wata ƙungiya mai mahimmanci da kwayar cutar da ke dauke da magungunan ƙwayar cuta, da ƙananan ƙwayoyin cuta, da masu cin hanci da zazzabi. Pain da kumburi su ne matsaloli masu yawa a marasa lafiya tare da lupus, kuma NSAID sun kasance magungunan zabi ga marasa lafiya da lupus mai laushi tare da kadan ko a'a ta hannu, duk da cewa FDA ba ta yarda da su ba don magance lupus. Marasa lafiya da ƙwayar cuta na kwayoyin halitta na iya buƙatar magungunan anti-inflammatory da immunosuppressive.
Duk da yake wasu NSAIDs, irin su na buprofen da naproxen, suna samuwa a kan kari, an buƙatar takardar likita don wasu. Za a iya amfani da NSAID kawai ko a hade tare da wasu magunguna don magance ciwo, kumburi, da zazzaɓi. Yana da muhimmanci ka dauki wadannan magunguna a karkashin jagorancin likita. Wani NSAID zai iya zama magungunan da ake bukata kawai don magance mummunar fushi, amma cutar mafi tsanani zai iya buƙatar ƙarin magunguna.
Abubuwan da ke cikin layi na NSAIDs sun hada da:
- Dama tada
- Ƙwannafi
- Diarrhea
- Rage riƙe ruwa
Wasu mutane kuma suna haɓaka hanta, koda, cututtukan zuciya, ko mawuyacin ƙwayar cutar ta hanyar amfani da NSAIDs, yana mai mahimmanci don zama a kusa da kusantar likita yayin shan waɗannan magunguna.
Kodayake duk NSAID sun bayyana aiki ne a daidai wannan hanya, ba duka suna da irin wannan tasiri ga kowane mutum ba. Bugu da ƙari, marasa lafiya na iya yin kyau a kan daya NSAID na lokaci kuma bayan wani dalili ba tare da dalili ba zai fara samun komai daga gare ta. Sauya zuwa NSAID daban-daban zai iya haifar da sakamakon da ake so. Ya kamata ku yi amfani da NSAID daya kawai a kowane lokaci.
Corticosteroids
Corticosteroids sune kwayoyin hormones da ke ɓoyewa daga kwayar cutar gilashi. Ana amfani da sifofin suturar kwayoyin nan ne a matsayin likita masu amfani da kwayoyi masu guba. Kalmar "steroids" sau da yawa fahimta kuma rikicewa zai iya haifar da lokacin da corticosteroids sun kuskure ga masu anabolic steroids.
Codicosteroids sun yarda da FDA don magance lupus kuma yawancin ana gudanar da su ta hanyar magana. A lokacin lokuta na rashin lafiya mai tsanani, ana iya gudanar da su cikin hanzari. Amma da zarar an daidaita ku, dole ne a sake dawo da gwamnati ta tsakiya. Saboda su kwayoyi ne masu karfi, likitanku zai nemi mafi ƙasƙanci tare da amfanin mafi girma.
Lupus marasa lafiya da bayyanar cututtuka da basu inganta ko wanda basu sa ran amsawa ga NSAID ko antimalarials za'a iya ba da corticosteroid. Kodayake corticosteroids suna da tasiri masu tasiri, suna da tasiri sosai wajen rage kumburi, rage tsoka da ciwon haɗin gwiwa da gajiya, da kuma kawar da tsarin rigakafi. Su ma suna amfani da su wajen kula da babban haɗin gwiwa da alaka da lupus.
Da zarar bayyanar cututtuka sun karɓa zuwa jiyya, yawancin yawancin ana yin amfani da shi har sai an sami kashi mai mahimmanci wanda zai iya gudanar da aikin cutar. Kuna buƙatar kulawa a hankali a wannan lokacin don fushi ko sake dawowa da haɗin gwiwa da ciwon tsoka, zazzabi, da kuma gajiya wanda zai iya haifar da lokacin da aka saukar da sashi.
Wasu marasa lafiya na iya buƙatar corticosteroids kawai a lokacin matakai na cutar; waɗanda ke fama da cutar mai tsanani ko mafi tsanani ga kwayoyin halitta zasu iya buƙatar magani na dogon lokaci. Doctors a wasu lokutan sukan ba da magungunan corticosteroid ta hanyar maganin lokaci kadan (kwanakin), wanda ake kira bolus far ko farfadowa.
Bayan daɗaɗɗen maganin corticosteroid, dole ne a dakatar da kwayoyi ba zato ba tsammani. Gudanar da corticosteroids zai haifar da gadon jikinka na maganin hormones don ragewa ko dakatar da, da kuma rashin jin dadin jiki ko ma rikice-rikice (yanayin yiwuwar rayuwa) zai iya haifar da idan an dakatar da miyagun ƙwayoyi. Yin amfani da kashi zai ba da damar jin dadin jiki na jikinka don farfado da sake ci gaba da samar da kwayoyin halitta. Da tsawon lokacin da kuka kasance a kan corticosteroids, mafi wuya shi ne rage kashin ko dakatar da amfani.
Corticosteroids amfani da su bi da lupus sun hada da:
- Prednisone (Sterapred) - mafi yawan lokuta don magance lupus; duba ƙarin ƙasa
- Hydrocortisone (Cortef, Hydrocortone)
- Methylprednisolone (Medrol)
- Dexamethasone (Decadron)
Corticosteroids suna samuwa a matsayin:
- Topical creams ko ointments (ga fata rashes)
- Allunan Labaran
- Liquid mafita
- Ƙungiyar steroid (intramuscular ko intravenous injections)
Hanyoyin sakamako na gajeren lokaci na corticosteroids sun hada da:
- Ƙara matsa lamba a idanu (glaucoma)
- Kusawa
- Hawan jini
- Ƙara yawan ci
- Amfanin nauyi
Sakamakon sakamako mai tsawo na corticosteroids na iya hada da:
- Cataracts
- Harshen jini (ciwon sukari)
- Cutar
- Rashin rauni ko kasusuwa kasusuwa (osteoporosis da osteonecrosis)
- Dogon lokaci don raunuka don warkar
- Sashin fata wanda ya fi sauƙi don karya
- Alamun alaƙa
Yawanci, ƙimar da ya fi girma da kuma tsawon lokacin da aka dauka, mafi girma da hadarin da kuma tsananin da tasiri . Idan kayi amfani da corticosteroids, ya kamata ka yi magana da likitanka game da karbar ciwon daji da kuma bitamin D ko magunguna don rage hadarin osteoporosis.
Karin bayani kan Prednisone
Prednisone shine maganin corticosteroid wanda likita ya rubuta, kadai ko tare da wasu magunguna, amma ana amfani da su azaman magani na gajere. Yana da matukar tasiri a zaluntar lupus mai aiki da kuma bayyanar cututtuka sau da yawa a cikin hanzari. Wadanda ke da ƙananan hali na lupus mai yiwuwa bazai buƙatar magani ba.
Tuntuɓi likita idan ka ci gaba da wani daga cikin alamomin da ke tattare da wadannan alamun da cewa bazai tafi ba ko kuma yana da tsanani yayin da kake ɗauka:
- Ciwon kai
- Dizziness
- Da wuya a barci ko barci
- Daidai mara kyau
- Girma yana canje-canje a yanayi
- Canje-canje a cikin hali
- Abun idanu
- Kuraje
- Muni, m fata
- Red ko m blotches ko Lines a karkashin fata
- Cire warkar da cuts da bruises
- Ƙara girma gashi
- Canje-canje a cikin hanyar yadu yana yada cikin jiki
- Babban gajiya
- Rashin tsokoki
- Ƙananan lokuta ko ɓataccen lokaci
- Rage sha'awar jima'i
- Ƙwannafi
- Ƙãra sweating
Tuntuɓi likitanku nan da nan idan kun fuskanci wani daga cikin wadannan alamun bayyanar yayin daukar nauyin:
- Matsaran hangen nesa
- Abun ciwo, redness, ko tearing
- Sashin ciwo, zazzabi, juyayi, tari, ko wasu alamun kamuwa da cuta
- Riƙe
- Dama
- Rashin haɗuwa da gaskiyar
- Rikici
- Muscle twitching ko tightening
- Shakan hannun da baza ka iya sarrafawa ba
- Murmushi, ƙona ko tingling a fuska, makamai, kafafu, ƙafa, ko hannayensu
- Upset ciki
- Vomiting
- Haskewa
- Ƙwararren zuciya
- Kyauta mai nauyi
- Kusawa ko ciwo a ciki
- Dama mai wuya
- Rash
- Hives
- Itching
Immunosuppressives / DMARDs (Magunguna masu gyaran maganin cututtukan cututtuka)
Immunosuppressives da sauran cututtuka masu amfani da cututtuka-cututtuka (DMARDs) ana amfani da su "lakabin" (ma'anar cewa FDA bai yarda da su ba don maganin lupus) don tsanani, lokuta masu kama da lupus inda manyan kwayoyin halitta kamar kodan suna shafi ko wanda akwai mummunan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ko ƙwayar ciwon ƙwayar cutar. Hakanan za'a iya amfani da immunosuppressives don rage ko wani lokaci kawar da buƙatar corticosteroids, don haka ya hana ku daga cututtukan cututtuka da ba a san su ba. Immunosuppressives sun dage magungunan ka mai kyau a hanyoyi masu yawa.
Immunosuppressives da DMARDs na iya samun mawuyacin sakamako mai mahimmanci. Duk da haka, abubuwan da ke cikin lalacewa suna dogara ne akan ƙimar da kake ɗaukarwa kuma suna da mawuyacin hali ta rage kashi ko dakatar da magani a ƙarƙashin jawabin likita. Wadannan kwayoyi za a iya ba da baki ko ta jiko (dripping da miyagun ƙwayoyi a cikin jikinka ta hanyar karamin tube).
Akwai matsaloli masu tsanani da suka shafi amfani da immunosuppressives da DMARDs. Wadannan sun haɗa da:
- Immunosuppression
- Ƙara ƙarami zuwa kamuwa da cuta
- Raunin marrow nema
- Ƙaddamar da mummunan aiki
Ana amfani da kwayoyi masu amfani da kwayar cutar da kuma sauran kwayoyi masu guba-maganin cututtukan cututtuka don magance lupus. Duk waɗannan sun shafi rukuni na magungunan da aka yi amfani dashi a matsayin layin kare na biyu akan lupus da sauran siffofin cututtuka. Kodayake suna da nau'o'i daban-daban na aiki, kowace nau'i na aiki don ragewa ko hana haɓakar da ba ta dace ba.
Immunosuppressives da DMARDs da ake amfani da su don bi da lupus sun hada da:
- Cyclophosphamide (Cytoxan)
- Mycophenolate mofetil (CellCept): Ana amfani da wannan magani ne don lupus nephritis ko tsarin magani na Lupus erythematosus, magungunan lupus, kuma yana taimakawa rage sashi na steroids da za ku buƙaci.
- Azathioprine (Imuran, Azasan): Azathioprine na aiki ne ta hanyar hana jigilar halittar jigilar jiki da kuma ƙarawa ta T. Bisa ga murine (linzamin kwamfuta da bera) da kuma nazarin mutum, ana ganin azathioprine wani wakili na immunosuppressive mai rauni. Duk da haka, yana da rahusa fiye da sauran magungunan immunosuppressive kuma za'a iya amfani dashi maimakon steroids. Musamman, azathioprine yayi aiki sosai bayan farawa da magani tare da cyclophosphamide ko mycophenolate.
- Methotrexate (Rheumatrex)
Magungunan maganin wadannan magunguna na iya haɗawa da:
- Jiɗa
- Vomiting
- Asarar gashi
- Mawuyacin matsaloli
- Rage haihuwa
- Ƙarin haɗarin ciwon daji da kamuwa da cuta
Rashin haɗari ga ilimin haɓaka yana ƙaruwa da tsawon magani. Kamar dai sauran maganin lupus, akwai yiwuwar sake dawowa bayan an dakatar da immunosuppressives.
Biologics
Benlysta (belimumab) wani magani ne na FDA wanda ya dace don magance masu aiki, masu kamuwa da kwayoyin halitta wadanda suka kamu da kwayar cutar, ciki har da corticosteroids, antimalarials, immunosuppressives, da kuma NSAID (kwayoyin masu maganin kare jini). An yi amfani da Benlysta a matsayin jigilar jini kuma shine kwayar farko don magance nauyin B-lymphocyte stimulator (BLYS), wanda zai rage yawan yawan kwayar halitta B-matsalar a lupus.
Zaɓuɓɓuka don Wasu Lupus Types
Idan an riga an gano ku tare da discoid ko cututtukan lupus cututtuka, yanayin da aka raba sau da yawa daga lupus erythematosus na jiki (SLE), dole ne a fara kula da plaques da farko tare da karin kirim mai corticosteroid ko kayan shafawa. Wadannan creams za a iya amfani da su a cikin rauni a daren kafin ka tafi barci; Ya kamata a rufe fatar jikin da fim mai filastik ko Cordran tef. Idan ana barin plaques ba tare da irin wannan murfin ba, ana yin amfani da kayan abinci da gels na corticosteroid sau biyu a rana.
Wata hanyar da za a bi gida ta bi da layin da aka yi ta hanyar labaran da ke da launi na lupus shine a yi amfani da masu amfani da lissafi na calcineurin kamar pimecrolimus cream ko tacrolimus maganin shafawa. Idan jikunan ku ba su amsawa ko dai masu corticosteroids ko masu kirkirar calcineurin, likitanku na iya gwada injecting corticosteroid a cikin kututtukan fata.
Idan babu wani daga cikin wa] annan maganin, likita zai iya gwada magani. Jigon farko na farko ya haɗa da antimalarials kamar hydroxychloroquine sulfate, chloroquine, ko quinacrine. Wadannan suna da tasiri ga yawancin mutane.
Idan antimalarials ba su yi trick, likita na iya gwada daya daga cikin wadannan jiyya na yau da kullum:
- Abunosuppressive, irin su methotrexate ko mycophenolate mofetil (MMF)
- Tsarin maganin tsarin jiki, irin su isotretino ko acitretin
- Dapsone, sulfonamide
- Thalidomide, wakili na rigakafi
Ɗaya daga cikin yiwuwar mummunan kwayoyin cutar antimalarial shine psoriasis, wanda shine wani nau'i na cutar fata wadda ke da alamun bayyanar cututtuka don juyawa da lupus cutane. Isotretinoin da thalidomide duka biyu ne, wanda ke nufin cewa wadannan kwayoyi zasu iya lalata tayin, saboda haka kada ka dauki wadannan idan kana da ciki ko tunanin yin ciki.
Ƙarin Magunguna dabam dabam
Saboda yanayin da farashi da kwayoyi da ake amfani da ita don magance lupus da yiwuwar cututtuka mai tsanani, mutane da yawa suna neman madadin wasu hanyoyin da za su magance cutar. Wasu hanyoyi masu zuwa sun haɗa da:
- Ƙananan Gurasa
- Ganye na kari
- Kifi na man fetur
- Taimakon Chiropractic
- Homeopathy
- Acupuncture
- Tai Chi
- Massage far
- Biofeedback
- Nuna tunani
Kodayake waɗannan hanyoyi bazai zama masu cutarwa ba da kansu kuma zasu iya taimakawa tare da wasu alamun bayyanarku idan an hade su tare da tsarin kulawa na yau da kullum, babu bincike don kwanan wata ya nuna cewa suna shafar tsarin cuta ko hana lalata kwayoyin halitta. A gaskiya ma, kari na kayan lambu na iya zama cutarwa, yiwuwar yin jigilar cututtukan lupus mafi tsanani da / ko tsoma baki tare da magungunan likitan ku.
Ku shawarci likita a koyaushe kafin ku fara aiki ko kuma magani, sannan ku tabbatar da ci gaba da shan magungunan da aka ba ku.
> Sources:
> Clarke J. Harkokin Gudanarwa na Discoid Lupus da Lupus Mutuwar Cututtuka. Na zamani. Updated May 16, 2017.
> Clarke J. Management na Refractory Discoid Lupus da Subacute Cutaneous Lupus. Na zamani. Updated Janairu 11, 2017.
> MedlinePlus. Prednisone. Ƙungiyar Ma'aikatar Medicine ta Amurka. Updated Nuwamba 15, 2015.
> Wallace DJ. Bayani na Gudanarwa da Tsarin Gida na Lupus Erythematosus a cikin Manya. Na zamani. Updated Janairu 24, 2018.