Epithelial Ovarian Cancer, Germ Cell, da kuma Jima'i-Cord Stromal Tumor Alamar
A matsayin ciwon daji na cutar ovarian, kai mai yiwuwa ya tsere a fadin kalmar nan "alamun tumo." Amma menene hakan yake nufi?
Magungunan Ovarian yana da suna saboda yana fitowa daga ovary (ko fallopian tubes kusa da ovary). Amma akwai nau'i daban-daban na sel a cikin ovaries , kuma kowane ɗayan waɗannan nau'in tantanin halitta zai iya zama abin ƙyama. Wadannan kwayoyin suna da nau'o'i daban-daban kuma suna samar da abubuwa daban-daban na biochemical.
Wadannan abubuwa za a iya auna su a jini kuma an kira su alamomin tumo.
Me yasa likitanku ya yi amfani da alamar tsabta?
A wasu lokuta, alamar tauraro wani abu ne da aka samar da shi kawai ta hanyar kwayoyin halitta. Duk da haka, a mafi yawan lokuta, waɗannan alamomi suna samuwa ne kawai a cikin matakan maɗaukaki kamar yadda kwayoyin cututtuka suka taso da sassa daban-daban na kayan aikin su na biochemical. Doctors na nufin ciwon daji wanda ke samar da mafi yawan waɗannan abubuwa kamar ciwace-ciwace da bayyana waɗannan alamomi. Alal misali, maimakon a ce cewa ciwon daji na ovarian ya haifar da yawancin CA-125, ba za su iya cewa ciwon daji ya bayyana CA-125 ba .
Dabbobin Ocersian Cancers
A kowane hali, wannan yana nufin cewa likitanku zai iya bincika jinin ku don gwada alamun alamar tumo, yana nuna abin da irin ciwon daji ke samuwa, ko daga bisani, yadda lafiyarku ke aiki. Yawanci, alamun ƙwayoyi suna karuwa a duk lokacin da magani yake da tasiri.
Mafi yawan ciwon daji na ovary ne ake kira epithelial ovarian cancer. Akwai ƙananan hukunce-hukunce uku: mucinous, serous da endometrioid. Mafi yawancin cututtuka na ovarian an kira su kwayar cutar kwayar cutar da ciwon sikila. Kowane ɗayan yana da ƙananan subtypes, amma alamu suna da iri ɗaya ga kowane ɗayan waɗannan ƙididdigar.
Epithelial Ovarian Cancer Tumor Masoyan
Kwayar cutar jini ta CA-125 alama ce mafi mahimmanci wanda aka yi amfani dashi ga wannan rukuni. CA yana nufin "antigen." CA-125 za a iya sanya shi ta hanyar kwayoyin halitta amma an sanya shi a cikin mafi yawan ƙwayar cuta a cikin wasu kwayoyin cutar Kanada fiye da kwayoyin jikinsu.
Ana iya amfani da CA-125 a matsayin ɓangare na lalata haɗarin cutar ta ovarian don tantance cutar ciwon daji, ko kuma ana iya amfani dasu don saka idanu ga amsawa ga jiyya na ciwon daji na ovarian. Ba duk likitocin ovarian ba ne ke bayyana CA-125, kuma matakan su ne al'ada a kusan kashi 20 cikin dari na irin wannan cutar ta ovarian. Sabanin haka, wasu ciwon daji na ovarian, tare da wasu yanayi, na iya haifar da matakin ƙaddamar da ca-125.
Daga cikin kashi 3 na ƙananan ciwon daji na ovarian, cututtukan mucinous suna da wuya su bayyana CA-125 fiye da koraji ko ciwon sukari.
HE4 - 'yan adam furoidymis protein 4 shi ne sabon sabon ƙwararren ƙwayar ƙwayar cuta wanda kuma za a iya bayyana a ciwon daji na ovarian, kuma kamar CA-125 ne mafi kusantar da za a samu tare da serous da kuma endometrioid ciwace-ciwacen daji. Wasu masu bincike sun gano cewa yin amfani da haɗin CA-125 da HE4 yafi taimakawa wajen bincikar ciwon daji na ovarian ko dai gwajin da aka yi amfani da shi kawai.
Tunda matan da ke da shekaru 40 suna iya samun launi na mucinous na ciwon daji na cutar ovarian, waɗannan alamun tumatir 2 na iya zama marasa taimako a cikin tsarin bincike don ƙananan mata.
Wasu alamomin ƙwayar ƙwayar cuta waɗanda sukan iya amfani da su a wasu lokutan don amfani da ƙwayoyin cutar shan-gadi na mucinous su ne CA-72-4, CA-19-9 da CEA (carcinoembryonic antigen). Akwai wasu waɗanda za a iya daukaka amma an yi amfani da su da yawa. CA 19-9 an samo shi ne a cikin mata tare da subtype mucinous kuma zai iya taimakawa a cikin tsarin bincike lokacin da aka haɗa tare da CA-125.
Gudun Tumatir na Germ-Cell
Abubuwan alamar biyu masu amfani da wannan rukuni na cututtuka sune: protein alpha-feto (AFP) da kuma gonadotropin chorionic dan adam (hCG) . Ana amfani da wannan karshen don kula da al'ada ta al'ada. Matsayi na AFP da hCG wanda aka haɓaka da muhimmanci shine hanya mai mahimmanci wajen bincikar waɗannan ciwace-ciwacen.
Jima'i mai launi na Stromal Tumor
Alamun kawai a cikin wannan rukunin da suke da amfani suna samar da subtype cellulosa cell. Wadannan sun hada da estradiol (irin isrogen) da kuma inhibin . Tun da yake ana samun waɗannan ciwon sukari a cikin matasan mata , waɗannan gwaje-gwajen za a iya kasancewa a matsayin wani ɓangare na wani aiki don wani taro na ciki (da kuma wasu alamomin bayyanar da suka faru) kamar yadda ya faru a cikin 'yan mata da mata.
Sources:
Berek, Johanthan S. "Cibiyar ilimin ilimin halayen ilmin halayen dan adam." Lippincott Williams & Wilkins, 2004
Carlson, K. Screening for Ovarian Cancer. Na zamani. Updated 03/01/16.
Hu, M., Guan, H., Lau, C. et al. Ɗaukaka akan ƙimar ƙwararren asibiti na β-hCG da αFP don ciwon ƙwayoyin cuta na intracranial germ cell. Turai Journal of Medical Research . 2016. 21 (1): 10.
Santororibio, J. Mene ne alamun tumatir da suka fi dacewa su gane cutar ciwon daji na ovarian? Ƙungiyar {asar Amirka ta Cibiyar Nazarin Harkokin Gina. 01/20/16.
Soletormos, G., Duffy, M., Hassan, S. et al. Amfani da cututtukan cututtuka na maganin cututtuka a cikin Epithelial Ovarian Cancer updated Guidelines Daga Ƙungiyar Turai a kan masu alama na Tumor. Jaridar kasa da kasa na Ciwon Gynecologic Cancer . 2016. 26 (1): 43-51.
Uma, D., Purushotham, N., Jayashree. Management of Ovarian Cancer a Ƙananan Mata. Bayani game da gwaji na asibiti . 2015. 10 (4): 263-9.