Yanayi biyu da ke haifar da tsufa
Ba abin mamaki ba ne don duban 'yan shekarunku ko ƙari fiye da ku. Amma, kwatanta tunanin shekarun da suka wuce ka tsufa. Ga mutanen da ke da kwayar cutar, kwayar halitta da ke haifar da tsufa, ba abu ne wanda ba a saba gani ba shekaru 30 ko fiye fiye da su.
Yayinda yake daukar kwayar cutar tare da Hutchinson-Gilford matsala, wannan lokacin yana iya komawa ga ciwo na Werner, wanda aka fi sani da balagagge babba.
Hutchinson-Gilford Progeria
Hutchinson-Gilford progeria yana da ban mamaki sosai, yana dauke da kusan 1 a cikin yara 4 zuwa 8. Yara da progeria suna da bayyanar al'ada lokacin da aka haife su. Kwayoyin cututtuka na yanayin fara nuna kowane lokaci kafin shekaru biyu lokacin da jaririn ya kasa samun nauyi kuma canjin fata ya faru. Sama lokaci. yaro ya fara kama da tsofaffi. Wannan na iya haɗawa da:
- Rashin gashi da gashi
- Musamman veins
- Sutattun idanu
- Ƙananan muƙamuƙi
- Kwancen hakori
- Hatsun ƙugiya
- Ƙananan ƙwayoyin hannu tare da manyan gidajen abinci
- Kwanan lokaci
- Rashin gabar jiki
- Low kasusuwa ( osteoporosis )
- Haɗin haɗin gwiwa
- Hanyoyin kwance
- Ciwon zuciya da atherosclerosis
Kimanin kashi 97 cikin dari na yara tare da progeria su ne Caucasian. Duk da haka, yara da yawa sun kamu da irin wannan hali duk da kabilansu daban-daban. Yawancin yara tare da progeria suna da rai kimanin shekaru 14 da suka mutu daga cututtukan zuciya.
Werner Syndrome
Werner ciwo yana faruwa a kusan 1 a cikin mutane miliyan 20.
Alamun Werner ciwo - kamar ɗan gajeren lokaci ko halayen jima'i waɗanda ba a haɓaka ba - na iya bayarwa a lokacin yarinya ko yaro. Duk da haka, bayyanar cututtukan yawanci ya zama sanannun sau ɗaya idan mutum ya kai shekaru 30. Kwayar cututtuka na iya haɗawa da:
- Rrinkling da sagging na fuskar
- Rage muscle taro
- M fata da asarar mai a karkashin fata
- Graying gashi da gashi gashi
- Kyakkyawan murya
- Abnormalities ƙwayoyi
- Sauke hanyoyi
Ƙungiyar Werner na faruwa sau da yawa a cikin mutanen ƙasar Japan da na al'adun Sardinia. Mutane da ke fama da cutar Werner sun tsira zuwa shekaru kusan shekaru 46, tare da mafi rinjaye ga cututtukan zuciya ko ciwon daji.
Bincike na gaba
Werner ciwo yana haifuwa ta maye gurbi a cikin wRN gene a kan chromosome 8. Damarar da aka haifar da maye gurbin a cikin layin LMNA akan chromosome 1. LMNA gene samar da Lamin A protein, wanda ke riƙe da tsakiya daga cikin kwayoyinmu tare. Masu bincike sunyi imanin cewa waɗannan kwayoyin maras tabbas suna da alhakin matukar tsufa da alaka da progeria. Masu bincike sunyi fatan da nazarin wadannan kwayoyin halitta zasu iya haifar da jiyya ga duka yanayin da kuma cutar da ta kawo karshen mutuwa ga mutanen da ke da siffofin progeria - kamar atherosclerosis da sauran cututtuka da ke haɗe da tsufa.
> Sources:
Kaiser, HW, (2002). Hutchinson-Gilford yayinda yake. eMedicine, isa ga http://www.emedicine.com/derm/topic731.htm
Cibiyar Nazari ta Progeria.
Kimiyya na Amurka.com. (1999). Menene mun san game da ciwon Werner da ciwon haihuwa, cutar da ke haifar da tsufa a cikin yara?
Wozniacka, A. (2002). Progeria (Werner ciwo). eMedicine