Duk da yake statins sun zama babban magungunan haɗarin haɗarin zuciya a cikin shekaru 20 da suka wuce, an yi jayayya a kan batun yadda tasirin ke amfani da ita a cikin mata. A tsawon shekaru, bayanai daga wasu gwaji na asibiti sun goyi bayan, amma ba a tabbatar ba, tasirin statins a cikin mata masu fama da cututtuka (CAD) . Tambayar ta dauki mataki mai muhimmanci ga ƙuduri a shekara ta 2015, duk da haka, lokacin da aka buga magungunan maganin gwaje-gwaje da dama a cikin asibitoci, sun kammala cewa statins a cikin mata suna da tasiri kamar yadda maza.
Me yasa Al'ummai suna da mahimmanci?
Yawancin kwayoyin sunyi mahimmanci a magani na zuciya saboda sune kwayoyi kawai na rage yawan ƙwayar cholesterol wadanda aka nuna su da tabbacin cewa zasu iya rage haɗarin ciwon zuciya, bugun jini, da kuma mutuwa a marasa lafiya.
A gaskiya ma, a yanzu ya zama a sarari cewa statins sunyi yawa fiye da rage ƙananan ƙwayar cholesterol - suna da mummunar sakamako mai kumburi; sun taimaka wajen hana jini marar kyau; suna taimakawa wajen tabbatar da ma'aunin da ke kan iyaka wanda rushewa yakan haifar da hare-haren zuciya da shanyewa; kuma suna da sauran amfani masu amfani kamar yadda ya kamata.
Hanyoyi masu amfani da kwayoyin kwayoyi don kare matsalolin zuciya, da aka rubuta a cikin gwaje-gwajen magunguna masu yawa, ya sa mafi yawan likitoci suyi farin ciki game da yin amfani da kwayoyi a marasa lafiya wanda ke dauke da kwayar cutar jini.
Me yasa akwai rikici akan ka'idodin cikin mata?
Tambayar ta wanzu saboda shaidar da cewa kwayoyin sunyi tasiri a inganta ingantaccen cututtukan zuciya ba su da mahimmanci a cikin mata fiye da maza.
Shekaru da yawa, gwajin gwajin gwaji da yawa da suka sanya sunayen maza da mata tare da ciwon haɗari na zuciya ( cututtukan zuciya) ko rashin ciwo na jijiyoyin zuciya , wato, a cikin mutanen da suka riga sun kamu da cututtuka (CAD) , sun nuna statins suyi tasiri a rage abubuwan da ke cikin zuciya, ciki har da hare-haren zuciya da mutuwa.
A cikin mutanen da ba su da CAD ba, amma a cikinsu akwai ƙimar CAD, ƙananan gwaje-gwaje sun nuna ingantacciyar sakamako na zuciya da na jini tare da statins, koda yake zuwa ƙananan digiri.
Amma idan ka bincika sakamakon da aka samo daga cikin matan da suka shiga cikin gwajin gwagwarmaya, amfanin da aka samu na statins sun kasa cimma matsayi na mahimmanci. Wato, amfanar da mazauni a cikin mata ba ta da kyau.
Mene ne Magana akan Wannan Babu Shaida?
Wannan ita ce inda gardama ta kasance. Akwai bayani biyu masu yiwuwa. Na farko, ba shakka, shi ne cewa watakila statins kawai ba sa aiki da mata kamar maza. Yawancin masana sunyi shakkar cewa wannan lamari ne. Magana ta biyu shine kawai cewa bai isa matan da aka sanya su a cikin gwaji na asibiti ba don tabbatar da tasirin statins. Hakika, a cikin mafi yawan waɗannan gwaji, girman da ake amfani dasu da statins ya kasance daidai ne a cikin mata kamar yadda maza, amma ba a ishe mata ba don isa ga muhimmancin ilimin lissafi a wannan matsala.
Mene Ne Sabon Shaida?
A farkon shekara ta 2015, an buga babban zane-zane a cikin rahoton Lancet cewa, lokacin da ake daukar nauyin cututtukan zuciya na zuciya, statins sunyi tasiri sosai a cikin mata fiye da maza.
Wannan bincike, wanda Cibiyar Harkokin Cutar Kwaro ta Cholesterol ke gudanarwa (CTT), yayi nazari da gwaje-gwaje 27 na asibitoci da aka yi da statins, wanda ya hada mata fiye da 46,000. Tattaunawar da yawancin matan sun yanke shawarar cewa statins sun kasance masu tasiri a cikin mata kamar yadda maza ke haifar da mummunan haɗari na manyan cututtukan zuciya. (Wadannan cututtukan zuciya na zuciya sun haɗa da hawan zuciya, bugun jini , buƙatar bugun zuciya ko zagaye tiyata , da kuma cututtuka na zuciya.) Amfanin sakamako na statins daidai yake ga maza da mata a kowane matsala na cututtukan zuciya.
Shin ya kamata a yi amfani da dokoki cikin mata?
Zamu iya cewa yanzu hujjoji mafi kyau sun nuna cewa statins suna da amfani a cikin mata kamar yadda suke a cikin maza, kuma kara, cewa jinsi ya kamata bai zama wani abu na yanke hukunci akan ko amfani da statins ko a'a ba.
Yanke shawara a kan farfadowa na statin ya kamata ya dogara ne akan matakin da ke dauke da kwayar cutar zuciya, da yin la'akari da hankali da kai da likitanka game da amfanin da ake samu na statins da kuma hadarin gaske. Yayin da ake buƙatar samun waɗannan yanke shawara a kowane lokaci, mafi kyawun shaida da ke samuwa yana nuna cewa jinsi bai bukaci taka muhimmiyar rawa a tsari na yanke shawara ba.
> Sources:
> Maganin ƙwayar cuta ta Cholesterol (CTT) Haɗin gwiwar. Ƙarfafawa da Tsaro na LDL-ragewan Farko tsakanin maza da mata: Meta-bincike na Ɗaukaka Bayanai daga 174,000 Mahalarta a cikin 27 Tambayoyi Randomized. Lancet 2015; DOI: 10.1016 / S0140-6736 (14) 61368-4.
> Davignon, J. Moriyar Lafiya na Kwayoyin Tsarin Kwayoyin Tsarin Lafiya na Statins. Yanayin 2004; 109: III39.
> Nissen, SE. Ƙananan ka'idoji na Statins a cikin ƙananan cututtuka na ƙwayoyin cuta. Ba kawai lakabi ne kawai ba. JAMA 2004; 292: 1365.