Mataki na farko a ganewar asali
Jaraba ga cutar celiac kusan kusan farawa tare da gwajin jini. Wadannan gwaje-gwaje na neman lafiyar jikinka ga gluten , furotin da ke cikin alkama, sha'ir, da hatsin rai wanda ke haifar da cutar celiac.
Jirgin jini ba cikakke ba ne. Idan jarrarin jini na celiac ya zama mummunan, yana nufin kai mai yawa zai iya samun cututtukan celiac, amma har yanzu akwai karamin damar da kake da ita.
Idan gwaje-gwaje na jini yana da tabbacin, yana nufin za ka iya samun cuta na celiac, ko da yake za ka kasance (a mafi yawan lokuta) buƙatar shan magani wanda aka sani da endoscopy don tabbatar da ganewar asali.
A lokacin da aka kawo karshen wannan likita, likitanku zai sanya tube ta ciki da kuma cikin saman ƙananan ƙwayarku, sa'an nan kuma a yanka kananan samfurori daga jikin jikin ku mai ciki don bincika a cikin microscope. Idan waɗannan samfurori na samfurori suna nuna launi maras kyau , lalacewar halayyar hanzari na samuwa a celiac cuta, to, kana da yanayin.
Haka ne, yana da tsari mai tsawo, kuma duk yana fara ne tare da gwajin jini na celiac.
Wadanne gwaji na jini ne ake yi
Cikin kwayar cutar ta Celiac na neman maganin rigakafin da ke nuna tsarinka na rigakafi ga mai cin abinci a cikin abincinka-wannan shine dalilin da ya sa kake buƙatar cin abinci lokacin da aka gwada ka ga cutar celiac. Idan ba ku cin abinci ba a lokacin gwaji, gwajin jini zai zama mummunan ko da kuna da cuta na celiac.
Akwai gwaje-gwaje biyar da za ku iya yi lokacin da aka jarraba ku don cutar cutar celiac:
- AGA (antigliadin antibodies) -IgA
- AGA-IgG
- tTG (transgutaminase nama) -IgA
- EMA (anti-endomysial antibodies) -IgA
- Kwayar magani IgA
Haka ne, dukansu suna kama da haruffa. Amma duk waɗannan gwaje-gwaje suna kallon sassan jikinka don ganin ko jikinka yana amsawa ga furotin mai gina jiki a cikin abincin da kuke ci.
Daga duk waɗannan gwaje-gwaje, gwajin EMA-IgA an yi la'akari da gwajin jini mafi kyau ga cutar celiac, ma'ana cewa idan kana da sakamako mai kyau a kan EMA-IgA, za ka iya samun cutar celiac. Duk da haka, EMA-IgA ma na iya rasa wasu mutane tare da cutar celiac, musamman idan sun fara fara inganta yanayin.
Idan kana sha'awar bayanan fasaha: EMA yana tsaye ne don maganin rigakafi, wanda shine kwayoyin cutar da jiki ke haifar da kansa. IgA, ko immunoglobulin A, shine nau'in antibody wanda jikinka ya samar. Ayyukansa shine don taimakawa jikin ya gano da kuma yaƙar maƙwabtaka da kasashen waje irin su muhalli, kwayoyin cuta, da ƙwayoyin cuta.
Sauran Kwancen Celiac Zai yiwu
Hannun jini da aka sani da AGA-IgA, AGA-IgG, da TTG-IgA kuma na iya nuna cewa jikinka yana amsawa ga furotin gine-gine ... kuma yana iya gane wasu mutane tare da cutar Celiac wanda yawancin gwajin EMA-IgA ya fi dacewa. misses.
Duk da haka, waɗannan gwaje-gwaje kuma na iya haifar da wasu siffofin ƙarya, wanda shine inda gwajin ya dawo tare da sakamako mai kyau, amma mutumin ba shi da cututtukan celiac. Abin da ya sa wasu masana kimiyya na celiac sun bada shawarar yin dukkan gwaje-gwaje tare-zaka iya samun cikakken hoto a hanya.
A wasu lokuta, mutanen da suka kamu da ciwon sukari, cututtukan thyroid , da kuma rashin lafiyar cutar hanta na autoimmune tabbatacce akan daya daga cikin waɗannan gwaje-gwaje, gwajin tTG-IgA, saboda sauran yanayi. tTG yana tsaye ne ga transglutaminase nama, wani enzyme wanda ke nunawa a cikin hanji.
Kyakkyawan tTG-IgA jini yana nuna cewa jiki yana haifar da kwayoyin cuta zuwa jikinsa, wanda zai iya faruwa a cikin amsawa ga cin hanci. Duk da haka, ba koyaushe yana nufin kana da cutar celiac, musamman idan kana da ɗaya daga cikin sauran yanayi da aka jera. Don haka idan kana da wasu daga cikin waɗannan ka'idoji, likitanka zai iya yin la'akari sosai a sakamakon sakamakon cutar ta jini.
A ƙarshe, jigilar gwajin jini na Celiac ya hada da gwaji da ke kallo nawa na daya daga cikin kwayoyin antibody, immunoglobulin A, jikinka ya sa. Wannan yana da mahimmanci saboda mutanen da suke da mummunan wannan mutumin (wanda aka fi sani da IgA) na iya haifar da mummunar sakamako akan cutar celiac cutar jini, koda kuwa suna da yanayin.
Kuma, wannan ya fi mahimmanci saboda mutane da cutar Celiac suna fama da wannan hali, wanda aka sani da rashi IgA , kimanin sau 10 zuwa 15 sau da yawa fiye da mutane a yawancin jama'a.
Wasu likitoci sunyi amfani da wannan daga cikin wadannan gwaje-gwaje- maganin antigliadin-IgG, ko kuma AGA-IgG- don nuna allon mutane don rashin fahimtar marasa lafiya . Duk da haka, masu bincike sun nuna ba daidai ba ne saboda wannan dalili, kuma a halin yanzu, masana kimiyya ba su samo gwaji mai kyau don ƙwarewa ba.
Celiac Gene Testing
Wasu likitoci sun bayar da shawarar gwaji ga wasu kwayoyin da ke ƙara yawan hadarin da ke fama da cutar celiac. Idan kun riga kuka fara cin abinci maras amfani , wannan zai iya zama gwaji kawai da likita ya ba da shawarar yin gudu (gwaje-gwajen da na bayyana a sama ba daidai bane idan kuna cin abinci).
Gwanar gwajin celiac ba sa neman magunguna zuwa gluten; maimakon haka, suna neman kwayoyin halitta guda biyu, HLA-DQ2 da HLA-DQ8 , waɗanda aka haɗa da cutar celiac. Kwayoyinku ba su canza ba, koda kuna cin abinci maras amfani.
Yanzu, gwajin gwaji na Celiac ba yana nufin kuna da cutar celiac-yana nufin kana da kwayoyin "dama" don yiwu ya bunkasa yanayin. Idan wasu gwaje-gwajen ku na jini ba su da kyau amma jarrabawar gwajin ku tabbatacce, ku da likitanku na iya yanke shawarar ku dakatar da cin abinci don yin gwaji don ganin idan wani cuta na celiac ya bayyana a fili.
Sources:
Nazarin Serologic da gwaji. Cibiyar Ciwon Celiac a Jami'ar Kimiyya ta Jami'ar Columbia.
Jami'ar Maryland Cibiyar Celiac Research. Celiac cuta: Tambayoyi da yawa akai-akai