Beta Amyloid Protein, Plaque, da Alzheimer's

Beta-amincin amyloid da plaque - wadannan kalmomi guda biyu da suke da alaƙa da kwakwalwa suna canzawa a cikin cutar Alzheimer. Kana so ka san ƙarin? Ga wadansu abubuwa 9 ne a gare ku:

1. Ginin fasahar bita-amincin amyloid a cikin kwakwalwa yana dauke da daya daga cikin alamun cutar Alzheimer . (Wani babban alamar mahimmanci shine ƙananan neurofibrillary .) Wadannan sunadarai na beta-amyloid sun hadu tare don samar da insoluble (ba za a iya narkar da su) ba a waje da ƙananan hanyoyi.

1. Ma'adinan Beta-amyloid suna ginawa a synapses kuma suna tsangwama tare da sadarwa daga wani cell zuwa wani a kwakwalwa.
2. Kafin rassan beta-amyloid ya isa ya kamata a kira shi plaque , wadannan sunadarai sun fara zama oligomers . Oligomers har yanzu soluble (iya rabu da su), karami kungiyoyin beta-amyloid.
3. Kodayake an gano alamomi a matsayin daya daga cikin abubuwan da Alzheimer ke haifar, masu bincike sun kira wannan a cikin kwanan nan, suna gano masu tayar da hankali kamar yadda ya kasance daya daga cikin manyan masu laifi a hana hana sadarwa daga tantanin halitta zuwa tantanin halitta. Ɗaya daga cikin dalilan da ke baya wannan shi ne cewa wasu mutane suna da tasiri a cikin kwakwalwa, amma basu da alamun cutar Alzheimer .
4. Bugu da ƙari, wasu bincike sun nuna cewa canje-canje na zuciya yana bayyana kafin farautar sunadarai na beta-amyloid daga ƙuƙwalwar ƙwayar allo.
5. Kimiyya ta gano sunadaran beta-amyloid fiye da 100 da suka wuce. Sunan farko ne Dokta Alois Alzheimer ya fara ganowa a 1906.

1. Beta-amyloid yana cikin ɓangare mai girma da ake kira amyloid precursor protein .
2. Tambaya mai ban sha'awa: "Masana kimiyya da dama sunyi tunanin cewa ƙila za a iya yin kwaskwarima ta kwakwalwa ta hanyar kwakwalwa domin samun wannan beta-amyloid mai kwakwalwa daga maɓuɓɓuka" (Alzheimer's Disease Education and Referral Center).
3. Binciken da aka gudanar a Cibiyar Ciwon Magunguna na Davis Alzheimer na UC ya gano cewa tsarin na rigakafi ya amsa daidai da hanyar da aka yi wa kwayoyin cutar, ta haifar da kumburi a kwakwalwa wanda ya lalata layi. Kutawa a cikin kwakwalwa an haɗa shi da cutar Alzheimer.

Sources:

_{Alzheimer's Association. Gwajin Alzheimer na gwaje-gwaje da ke tattare da Beta-Amyloid da "Amyloid Hypothesis." 2008.}

_{Alzheimer's Association. Ƙarin Game da Plaques.}

_{DANA Foundation. Amyloid-Beta 'Oligomers' na iya zamawa zuwa lalatawar Alzheimer. Yuli 12, 2010.}

_{Ƙungiyar Ƙungiyar Ƙungiyoyin Ƙasar. Cibiyar Ilimi da Cibiyar Bincike ta Alzheimer. Janairu 22, 2015.}

_{Medicine Stanford. Masana kimiyya sun nuna yadda Beta-amyloid zai iya haifar da Alzheimer's. Satumba 2013.}

_{UC Davis Health System. Alzheimer yana haifar da Amyloid da kuma Bacteria na Tambaya Sakamakon Amsa.}