Yawancin lokaci, Rigakafin, da cututtukan cututtuka na wannan sakamako na Rituxan
Maganin rashin tausayi ga Rituxan, wanda aka fi sani da MabThera ko Rituximab , sune magungunan wannan maganin da ake amfani dasu don maganin lymphoma da sauran cututtuka. Mene ne alamun rashin lafiyar jiki da kuma yadda ake gudanar da aikin?
Bayani
Rituxan wata maganin ƙwayar cuta ne guda daya , yana nufin cewa yana ƙaddamar da ƙwayoyin kwayoyin (CD-20) wanda yake kan wasu kwayoyin halitta ba tare da kariya ba - jinin fararen fata wanda shine tushen lymphomas, amma wannan mahimmancin magunguna ne a wasu cututtuka masu cutar rigakafi, irin su rheumatoid arthritis.
Rituximab magani ne mai mahimmanci a lymphoma ba na Hodgkin (NHL) kuma an nuna shi don inganta rayuwa a wasu nau'o'in NHL da suka hada da lymphoma da ƙananan lymphoma da yawa .
Rituximab ya ƙunshi ƙananan adadin furotin daga nau'in linzamin kwamfuta. Saboda haka, rituximab an san shi da "mai yaduwar kima," wanda ke nufin an yi shi daga sassa da ke fitowa daga nau'i daban daban. Duk da yake wannan yana da mahimmanci ga miyagun ƙwayoyi ya yi aiki, jikinmu suna da kyau don gane alamomin kasashen waje da mamaye masu haɗari da kuma fara farawa a kan su. Maganin rashin lafiyar daga rituximab kullum yana karuwa ga sunadarin protein a cikin miyagun ƙwayoyi.
Kafin rituximab an yi amfani da shi, zamu iya magance magunguna wanda zai rage yiwuwar za ku sami wani rashin lafiyan. Wannan ya hada da Tylenol (acetaminophen) da Benadryl (diphenhydramine) da kuma wasu magungunan maganin steroid.
Tun da diphenhydramine zai iya sa ku barci, yawanci ana ba da shawara cewa kuna da wani ya fitar da ku gida bayan jiko.
Alamai da cututtuka
Abubuwa na yau da kullum na farfadowa na rituximab sune:
- Fuskantarwa da raguwa - waɗannan su ne halayen da suka fi dacewa kuma sun faru a mafi yawan mutane
- Jiɗa
- Itching
- Rash
- Gurasa fuska ko watering daga hanci
- Kusa hannun, ƙafa ko fuska
- Ragewa a cikin karfin jini da kuma rashin hankali
- Spasm na makogwaro, kama da fuka
- Ciwon kai
Wadannan cututtuka sun faru a cikin minti 30 zuwa 2 na fara farawa da miyagun ƙwayoyi kuma zasu iya kasancewa tare da farkon jiko ( kimanin kashi 80 cikin dari na marasa lafiya suna da karɓa ) kuma sun zama ƙasa da gajeren lokaci.
Kusan, halayen haɗari na iya faruwa, ciki har da:
- Matsalar numfashi mai tsanani
- Zuciyar zuciya
- Kyakkyawan lalacewar karfin jini da girgiza.
Jiyya
Idan kana da wata amsa ko da yake duk abin da aka ba ku kyauta ne, abu na farko da likita ko likita ya yi jinkiri ko dakatar da jiko. Don wasu halayen halayen, wannan shine abin da ake bukata. Ana iya yin amfani da kwayoyi don ragewa ko dakatar da amsawa. Wadannan sun hada da acetaminophen, antiallergics, IV saline ko kwayoyi don kara yawan jini da kuma steroids. A kusan dukkanin marasa lafiya, ana iya sarrafawa da sauri tare da waɗannan matakan. Saboda halayen haɗari, ɗakunan kulawa mai kulawa na iya zama mafi dacewa-da matakan kula da kula da jini da numfashi. Kodayake an bayar da rahoton mutuwar daga halayen jure-jita, suna da wuya.
Rigakafin
Ƙarin ƙananan za su iya hana ko rage rashin haɗari da haɗari tare da rituximab:
- Magunguna. Kamar yadda muka gani a sama, zaku iya daukar magungunan antihistamine da kuma steroid kafin jiko.
- Fara da jiko sannu a hankali. Wannan yana da mahimmanci ga farkon jiko lokacin da halayen su ne mafi mahimmanci. Ana amfani da jita-jita da hankali cikin sauri kuma ana ƙara yawan jimillar lokacin da babu wani halayen da ya faru.
- Tsayawa shan magani na jini kafin infusions. Tunda fashewar cutar hawan jini zai iya faruwa a lokacin wani abu, wasu likitoci sukan umurci marasa lafiya su dakatar da yin amfani da magungunan maganin jini a gaban jiko. Ya kamata kuyi haka kawai a karkashin umarnin musamman daga likitanku, duk da haka.
Wadanda suka yi aiki mai kyau ko tsakaita tare da rituximab za a iya ba da miyagun ƙwayoyi a hankali kuma suna buƙatar daukar duk kariya ga wasu jiyya. Wadanda suke da halayen halayen halayen ba sa yin amfani da kwayar magani ba.
Sources:
LaCasce, A., Castells, M., Burstein, M., da J. Meyerhardt. Hanyoyin haɗuwa ga magungunan ƙwayoyin cuta guda daya da aka yi amfani da su don maganin ciwon daji. Na zamani. Updated 01/08/16. http://www.uptodate.com/contents/infusion-reactions-to-therapeutic-monoclonal-antibodies-used-for-cancer-therapy