Kila ka ji asibirin mai tsanani na numfashi (AERD) an kira Samter ta triad ko aspirin-induced fuka. Akwai sharuɗɗa uku waɗanda mutane da AERD duka suna da: fuka, ciwon sinus tare da ƙananan polyps , da kuma kulawa da magungunan da ake kira NSAIDS (musamman aspirin da sauran magunguna da ke toshe wani enzyme mai suna COX-1).
AERD yana shafar kashi 0.3 zuwa kashi 0.9 na yawan jama'a kuma kashi 10 zuwa 20 na mutanen da aka gano da ciwon asma. Duk da haka, ba a fahimtar ilimin ilimin lissafi ba. Kamar yadda ya shafi dukkanin kabilanci daidai, tare da shekaru 35 da haihuwa, amma ba ze gadon sarauta ba kuma zai iya shafar mata fiye da maza.
Idan ka yi tsammanin ganewar asali ko an gano shi, ana samun dama don taimaka maka ka gudanar da bayyanar cututtuka kuma ka rayu da kyau. Ga abin da kuke buƙatar sani.
Cutar cututtuka
Idan kana da AERD zaka iya sha wahala daga haɗuwa da wasu ko duk wadannan alamun bayyanar:
- Nawa sinusitis
- Nasal polyps
- Asarar wari
- Asthma
- Sakamako ga NSAID (aspirin ko magungunan magungunan), wanda zai iya haɗawa da haɗari na hanci, flushing, ciwon kai, sneezing, coughing, wheezing, bronchospasm, laryngospasm ko zafi ciwo. Wadannan bayyanar cututtuka na iya faruwa bayan shan barasa.
Kuna iya wahalar maganin bayyanar cututtuka ta hanyar al'ada.
Misali, ƙananan polyps na iya canzawa cikin hanzari bayan an kawar da su a jiki. Raguwa da numfashi na numfashi zai iya haifar da wahalar barci da dare da damuwa na barci da kuma gajiya da rana.
Har ila yau, kowa yana iya samun ciwon cututtuka wanda zai iya cutar da AERD.
Wadannan na iya haɗawa da rhinosinusitis mai ciwo, ko GERD, ko fuka-fuka-fuka . Dole ne a gudanar da waɗannan sharuɗɗa daban daga AERD kuma likitanku zai iya bayar da shawara ga mafi kyau.
Sanin asali
Idan kana da ciwon fuka, ƙwayar sinus tare da ƙananan polyps, kuma sun yi ko kuma ana zargin kana da wani abu ga wani NSAID, likita za ka iya zaton kana da AERD. Ƙarin gwaje-gwaje zai taimaka wajen tabbatar da wannan ganewar.
Ɗaya daga cikin gwaji shine gwagwarmayar aspirin, wanda ya shafi bada aspirin a cikin 'yan kwanaki a wani wurin likita inda za a iya kula da ku don amsawa. Bayan ya ba ku aspirin asibiti likitanku na iya gwada gwajin ku don ganin idan ya rage.
Kwararka na iya zaɓi izinin sauran gwaje-gwaje don taimakawa wajen ganewar asali na AERD, ciki har da gwaje-gwaje na jini. Eosinophils su ne fararen jini, wadanda aka gyara na tsarin rigakafi. Mutanen da ke da AERD suna da ƙananan adadin eosinophils a cikin ƙananan polyps na ƙananan su kuma suna iya kara girman jini. Sauran kwayoyin halitta marasa yaduwa irin su sassan mast na iya haɗuwa. Zaka kuma iya samun matakan tayi na wani abu da ake kira cysteinyl leukotrienes. CT scans, ko wasu gwaje-gwajen hotunan don taimakawa wajen ganin hotonku.
Ya kamata a lura cewa babu wani daga cikin waɗannan gwaje-gwaje da aka tabbatar don ganewar asali na AERD amma zai iya taimaka wa likitan ku sami ƙarin bayyani game da yanayinku.
Jiyya da Gudanarwa
Babu magani don AERD, kuma kamar yadda aka ambata a baya labarin cutar wannan ilimin da masana kimiyya da likitoci suka fahimta. Duk da haka, akwai nau'o'in magancewa da yawa don taimaka maka wajen sarrafa bayyanar cututtuka.
Ɗaya daga cikin zabin shine kaucewa aspirin da sauran magunguna NSAID (duk wani maganin da zai hana inzyme COX-1). Ana iya amfani da acetaminophen maimakon wadannan magunguna, amma zai fi dacewa a cikin ƙananan ƙwayoyin (har zuwa 500mg).
Kaucewa aspirin ba zai sarrafa sauran bayyanar cututtuka kamar na polyps na nasal, cututtuka na sinus ko alamar fuka ba.
Ci gaban ƙananan polyps za a iya jinkirta ta hanyar yin amfani da injections, maganin cirewa, ko haɗuwa da duka biyu. Hakanan da ke dauke da steroids da ban ruwa na banki na iya zama mahimmanci wajen sarrafa wasu bayyanar cututtuka da matsalolin sinus.
Ana amfani da magungunan montelukast da zafirlukast sau da yawa kuma sun kasance suna taimakawa wajen sarrafa bayyanar cututtuka fiye da sauran magunguna, ciki har da beta-agonists. Ana amfani da corticosteroids inhaled don gudanar da asma kuma yana iya zama wajibi don amfani da waɗannan magunguna a kullum. Lokaci-lokaci ana amfani da maganganun maganganu, amma gaba daya idan wasu magunguna sun kasa kula da bayyanar cututtuka tun lokacin da steroid din ke da ƙananan sakamako.
Asalin Wutar Aspirin
Wani zabin, wanda ya nuna ya fi tasiri, shine shan lalata aspirin. Nazarin ya nuna cewa aspirin desensitization wanda ya dace da maganin aspirin na yau da kullum zai iya rage yawan kwayoyin polyps da cututtuka na sinus da kuma inganta yawan asibirin.
Ana bada aspirin a wani wuri na likita inda za a iya kula da ku don amsawa. Gidajen likita yawanci a asibitin tare da ma'aikatan lafiyar likitanci (rashin asibiti na gaggawa ba ya zama dole). Sanda ya fara ƙananan kuma an ƙara hankali sosai a cikin adadin don rage tsarinka zuwa magani. Wannan kuma kama da lura da immunotherapy don allergies.
Shaidun shaida suna nuna cewa asusirin aspirin yana da tasiri sosai kuma yana da amfani ga yawancin mutane da ƙwarewar AERD. Ingantawa na iya zama sananne bayan makonni hudu na jiyya. Nazarin ya nuna ingantaccen ƙwayar hanci, jin wari, da rage yawan adadin magani da ake buƙata don sarrafa cututtukan fuka.
Ba duk mutanen da ke tare da AERD sun cancanci yin amfani da aspirin ba. Bai kamata ku yi wannan magani idan kun kasance cikin ciki ba, kuna da ciwo na ciki, ciwo na jini, ko kuma alamar fuka-fuka mara lafiya.
Akwai hadarin da ke haɗuwa da aspirin ƙarancin kuma waɗannan sun hada da kafa tsarin bayyanar cututtuka na AERD ciki har da matsaloli mai tsanani na numfashi. Har ila yau, duk wani illa da zai iya faruwa yayin shan aspirin, irin su matsalolin ciki ko zub da jini, na iya faruwa a lokacin aspirin desensitization. Ya kamata ku yi magana da likitanku ko likitan magunguna game da illa mai tasiri da kuma tabbatar da cewa aspirin ba zai tsoma baki tare da wasu magunguna da za ku iya ɗauka ba.
Bayan da ka shafe aspirin ne ya zama dole don ci gaba da daukar nauyin aspirin a kowace rana don ci gaba da ragewa. Da farko wannan nauyin zai iya zama kamar mikoli 1300 a kowace rana amma, ya dace, likita zai rage yawan aspirin da kake ɗauka. Yawanci a matsayin m kamar 81mg a kowace rana (magani na musamman ga mutanen da ke fama da ciwo na zuciya) sun nuna tasiri.
Idan kullun da kullun da kake karantawa sun shafe ka, ka sani cewa tsari shine mataki-mataki, don haka gwada kokarin mayar da hankali akan abu ɗaya a lokaci guda. Kwarar ku zai jagoranci ku a ko'ina, kuyi tasiri na illa, kuma ku san duk wani takaddama.
> Sources:
> Aspirin-Exacerbated Respiratory Disease (AERD). Cibiyar Nazarin Harkokin Alkawari da Immunology ta Amirka. https://www.aaaai.org/conditions-and-treatments/library/asthma-library/aspirin-exacerbated-respiratory-disease
> Rachel U. Lee da Donald D. Stevenson. Aspirin-Exacerbated Disease Respiratory: Evaluation da Management. Allergy Asthma Immunol Res. 2011 Jan; 3 (1): 3-10.
> John W Steinke da Jeff M Wilson. Aspirin-mafi tsanani da cututtukan cututtuka: ilimin lissafi da kuma ci gaba na asibiti. J Allergy Asthma. 2016; 9: 37-43.