Viagra (sildenafil citrate) da wasu magungunan kwayoyi don cin hanci da rashawa (ED) sunyi tsammanin wani lokaci ne mai yiwuwa sanadin hasara, ko da yake haɗin yana har yanzu ana binciken kuma ba a sani ba.
A lokacin Viagra ya amince, a shekarar 1998, Cibiyar Abinci da Druggun Amurka (FDA) ta gano cewa mutane biyar daga cikin 25,000 na amfani da Viagra a cikin gwaji na gwaji sun ji daɗin hasara .
Wannan ƙananan ƙananan lambobi ne, wanda shine dalilin da yasa gargadi game da hasara mai ban mamaki ba a lokacin da aka yarda.
Duk da haka, tun daga ƙarshen shekara ta 2007, FDA ta fara fara lura da wasu lokuta na rashin jin daɗi a cikin mutane da ke dauke da Viagra da sauran kwayoyi ED waɗanda suke cikin ɓangaren magungunan phosphodiesterase Type 5 (PDE5). Sauran kwayoyi na PDE5 sun haɗa da Levitra (vardenafil) da Cialis (tadalafil).
Binciken tsarin da aka ba da rahotanni na banbanci, FDA ta gano sharuɗɗa 29 na kwatsam a cikin kwana uku na kwanan baya na marasa lafiya na PDE5. Irin irin lalacewar da aka ji ya ruwaito shi ne yawancin lalacewa na jijiyar jijiyar koyon rashin jin dadin jiki ko kuma duk wani ɓataccen sauraron sauraro. Wani lokaci tinnitus da dizziness sun shiga.
Shafuka goma sha biyar daga cikin abubuwan da ke faruwa a cikin 29 sune alaka da Viagra musamman. A cikin lokuta biyar, kwatsam yaron ya faru bayan da farko na Viagra. Mutane tara sun sami lalacewar jihohi da kuma mutum daya da ya ji rauni.
Takwas daga cikin mutane 15 sun kasance da "ci gaba" sauraron sauraro kuma mutane hudu suna da asarar sauraron lokaci.
Wadannan rahotanni baza'a iya haɗuwa da su ba tare da maƙallafin PDE5 saboda yiwuwar wasu abubuwa, irin su shekarun mai haƙuri da kuma amfani da wasu magunguna. Duk da haka, FDA ya bayyana cewa yana da damuwa don buƙatar canje-canje a cikin lakabin labaran ƙwayoyi don faɗakar da hankali ga yiwuwar sauraron ji.
Zaku iya sauke wannan bayanin daga shafin yanar gizon FDA.
FDA ta yi la'akari da cewa idan ka fara jin dadi a yayin Viagra ko wani magani irin wannan, ya kamata ka daina dakatar da shan shi kuma tuntuɓi likitanka. Hakazalika, likitocin da suka fahimci cewa marasa lafiya suna fama da lalacewa yayin da waɗannan kwayoyi zasu shawarce su su dakatar da daukar su.
Lab Naz
Shin za a tabbatar da cewa Viagra yana sa sanadin hasara a cikin mutane? Wasu masu bincike suna kokarin ganowa. Masu bincike a Koriya ta Kudu sunyi nazari akan 'yan mata maza bakwai da suka gabata. A tsawon kwanaki 105 an ba da wasu ƙwayoyin Viagra. Sauran ƙananan yara ba a ba Viagra ba ne kuma sun kasance ƙungiya mai kulawa domin kwatantawa. Duk kungiyoyin biyu sun ji gwaje-gwaje kafin binciken da kuma a cikin kwanaki biyar, 10, 15, 25, 35, 105 da 135 na binciken.
An jarraba su a hanyoyi masu yawa, ciki har da amsoshin kwakwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa da kuma watsi da tsirrai. Kwakwalwa mai kwakwalwa ta yadda ya dace da yadda kwakwalwa ke amsawa. Hanyoyin tsirrai masu tsirrai ne ƙananan ƙararrakin da kunne ya haifar bayan ya ji sauti. Sakamakon ya nuna cewa Viagra ya karu da karfin sauraron sauraron maganganun kwakwalwa na kwaskwarima.
Wato, sauti ya kasance mai ƙarfi don yada amsa. Bugu da ƙari, magungunan tsirrai na zamani sun bambanta tsakanin ƙananan mice da ƙwayoyin kulawa lokacin da aka ba da magani ga dogon lokaci.
Masu binciken sun yanke shawarar cewa babban kashi da magani na dogon lokaci zai iya haifar da hasara a cikin yara. Za a iya samun sakamako irin wannan a cikin mutane? Masu bincike sun ba da misalin misalin dan shekaru 44 wanda ya sami asarar labari bayan ya ɗauki Viagra a 50 milligrams a rana na kwanaki 15.
Ko da yake ba a tabbatar da ita ba cewa Viagra da sauran magungunan PDE5 suna haifar da hasara a cikin mutane, shaidar da ƙungiyar ta ci gaba da shiga.
Wannan ƙungiyar tana tallafawa ta nazarin dabba kamar na sama. Ya zuwa yanzu, shaidun da aka samo suna nuna rashin lafiya ne, amma masana kimiyya suna ci gaba da kira don ƙarin bincike.
Sources:
Bin Na Hong, Ta Yi Hoo Yi, Sun Yeou Kim da Tong Ho Kang, "Sildenafil Mafi Girma Yana Da Raunin Jiji a Mice", Biol. Pharm. Bull., Vol. 31, 1981-1984 (2008).
Magungunan ƙwayoyin cuta masu tsabta da kwatsam da kuma kwatsam ji. (BABI NA BUKATA MUHAMMADI FDA don masu sauraro) Audiology a yau. Nov-Dec 2007 v19 i6 p53 (1).
Bayanin layi na Viagra. An shiga ta hanyar http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm
Bayanin lafiyar miyagun ƙwayoyi na asibiti ga marasa lafiya da masu samarwa. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124841.htm