Rashin ciwon Lynch ko ciwon daji na ciwon daji (HNPCC) yana kara haɗarin ci gaba da cigaba da sauran cututtuka. Kula da lafiyar lafiya da kuma cikakken shirin ciwon daji na iya gudanar da waɗannan hadarin.
Lynch Syndrome (HNPCC), Genetics, da Family Families Colon Cancers
Kimanin kashi 75% na ciwon daji na ciwon sukari ne. Wannan yana nufin ba su da masaniya game da kwayoyin halitta ko sun rubuta tarihin iyali don mutumin da aka gano da cutar.
Daga cikin sauran maganganu na ciwon ciwon ciwon daji shine Lynch ciwo ko cike da cutar rashin ciwon daji (HNPCC).
Lynch ciwo na asali na kashi 2-7% na cutar kankara da aka gano a Amurka. Ganin cewa kimanin mutane 160,000 ne aka gano tare da ciwon ciwon ciwon kowa a kowace shekara, wannan yana nufin tsakanin 3,200 da 11,200 na lokuttan ciwon daji na ciwon sutura wanda ake iya haifar da Lynch syndrome.
Tare da kara yawan ciwon daji na ciwon mallaka, mutanen da ke fama da ciwon Lynch na iya haifar da haɗarin ci gaba da ciwon daji, ciki har da ciwon sukari, ƙwayar ciki, ƙananan hanji, hanta gallbladder ducts, ƙananan urinary, kwakwalwa, fata, prostate, mahaifa ( endometrium), da ovaries. Iyayen da Lynch ciwo ke kasancewa suna da tarihin iyali na ciwon daji. Tare da gwajin kwayoyin gwagwarmaya da yawa, yawancin wadannan iyalai sun san cewa suna da canjin halittar da ke haifar da ciwon Lynch.
Wannan kuma shine dalili yana da muhimmanci a rubuta tarihin iyalinka.
Mutane sau da yawa ba sa tunanin wasu cututtuka kamar haɗin kai, amma idan aka hada tare da haɗin ke bayyana.
Ta Yaya Lynch Syndrome Ya Sami?
Lynch ciwo ya shige daga iyaye zuwa yara saboda canje-canje a cikin jinsin hudu: MLH1, MSH2, MSH6, da PMS2. Jinsin su ne jagoran horo don ginawa da kuma gudana jikin mutum.
Kusan dukkanin tantanin halitta a cikin jikinmu sun ƙunshi nau'i biyu na kowace jinsin. Ɗaya daga cikin mahaifiyar ta fito ne daga mahaifiyarka kuma ɗayan ya zo daga mahaifinka. Ta wannan hanyar, idan mahaifi ko iyaye suna canje-canje a daya ko fiye daga cikin kwayoyin da ke haifar da ciwon Lynch, zasu iya canza wadannan canje-canjen ga 'ya'yansu, lokacin da suke tafiya tare da jikinsu.
Ga wasu cututtuka, idan daya daga cikin jinsunan biyu ya lalace ko bace, ɗayan, kwafi mai kyau, zai yi aiki kullum kuma babu wata cuta ko ƙari ƙari. Wannan ana kiran shi alamar tacewa .
Ga wasu cututtuka, ciki har da ciwon Lynch, idan har ko da guda ɗaya daga cikin jinsin ya lalace ko ya ɓace, wannan ya isa ya kara haɗari ko haddasa cuta. Wannan ana kiran shi hoton mamba. Duk da haka, yana da mahimmanci a tuna cewa kawai mafi yawan hadarin ciwon daji shine ya gaji a cikin mutanen da ke fama da ciwon Lynch. Ciwon daji ba nasaba ne kuma ba duk wanda ke da ciwon Lynch zai ci gaba da ciwon daji ba.
Bugu da ƙari ga ciwon Lynch, akwai wasu hanyoyin haɗin gwiwar ciwon daji wanda ke da mahimmanci don fahimta kuma yana yiwuwa ma za'a iya gano ƙarin haɗi a nan gaba.
Kariya mafi kyau
Abin godiya muna rayuwa a cikin wani lokaci wanda ba dole ba ne kawai ku jira ku gani.
Akwai hanyoyi na kimanta kwayoyin halittu, kuma koda mutum yana da hadarin kwayoyin halitta, muna koya game da wasu hanyoyi don rage wannan hadarin. Samun tarihin iyali na ciwon daji ba abu ne mai komai ba lokacin da yake ƙarfafa mutane su kula da lafiyarsu. Misali na wannan yana tare da ciwon nono, wanda kusan 10% yana da haɗin gwiwar kwayar halitta. Matan da ke da tarihin iyali suna tabbatar da cewa an kware su kuma kada su jira don a cire kullun. Idan sun ci gaba da ciwon daji, za'a iya samun su a baya fiye da wani a cikin 90% wanda ba shi da damuwa saboda rashin tarihin iyali.
Yin tunani game da irin wannan ra'ayi na wannan hanya ya taimaka wa wasu mutane su magance haɗarsu.
Nazarin Halitta
Idan ka gano cewa kana da ciwon Lynch, ka yi magana da likitanka game da samun mai nunawa don ganin mai ba da shawara. Kwararka zai iya taimaka maka ka sami shawara a kan yanki a yankinka ko zaka iya bincika shafin yanar gizo na Ƙungiyar Tattalin Arziki ta Kasa don gano albarkatun gwaninta. Ganin shawarar mai ba da shawara a cikin kwayar mahimmanci ne saboda ba duk canzawa a jikin kwayoyin cutar suna haifar da matsanancin ciwon daji ba. Wasu canje-canje na iya ƙara haɗari kadan kawai, yayin da wasu canje-canje na iya ƙara yawan haɗarin ciwon daji. Yana da muhimmanci a san ainihin hadarinka don ku iya shirya wani shiri don sarrafa shi.
Ruwan Cancer
Abu na biyu mai muhimmanci da za ku iya ɗauka shi ne magana da likitanku game da shirin ciwon kanji. Domin yawancin ciwon daji, ciki har da ciwon daji, ana iya samun gwaje-gwaje masu sauƙi. Kuma ko da magungunan ciwon da ba su da gwajin gwaje-gwajen da aka tsara, kayan aikin kamar CT da kuma gwajin MRI za a iya amfani dasu don gano ciwon daji a farkon matakan, lokacin da ya fi dacewa.
Yayinda sunan ciwon dabaran kwayoyin cutar ciwon daji ya nuna cewa, wannan yanayin yana kara yawan ciwon daji na ciwon ciwon daji ba tare da kara yawan hawan polyps ba. Polyps suna ci gaba a cikin ciwon da cewa idan ba a gurgunta ba, za su iya ci gaba da ciwon ciwon daji. Wannan ba yana nufin cewa mutane da Lynch ciwo ba zasu taba samun polyps ba. Yana nuna kawai cewa sukan cigaba da cigaba da ciwon ciwon ciwon ciwon ciwon daji ba tare da sun fara bunkasa polyps ba. Saboda wannan dalili, tantancewar maganin wannan cuta zai iya zama ƙalubale, amma bincike yana goyon bayan cewa colonoscopy yana gane magungunan ciwon daji da ke hade da Lynch ciwo. Colonoscopy wani ɓangare ne mai muhimmanci na kula da ciwon Lynch.
Kila za a buƙaci a duba ku tun daga lokacin ƙuruciyar kuma yawanci fiye da mutane ba tare da ciwon Lynch ba. Duk da yake wannan yana iya zama kamar babbar matsala, yana daya daga cikin hanyoyin mafi kyau don gudanar da yawan ciwon ciwon daji, ciki har da ciwon daji.
Akwai Albishiri
Duk da yake ba wanda yake so ya samu ciwon Lynch, akwai wani labari mai kyau game da wannan yanayi. A shekara ta 2008, masu bincike na Italiya sun wallafa bincike da nuna cewa marasa lafiya na ciwon daji marasa lafiya da Lynch ciwo sun fi kyau fiye da sauran marasa ciwon daji. Mutanen da ke fama da Lynch ciwo sun fi rayuwa mafi kyau, tare da 94% daga cikin wadannan marasa lafiya har yanzu suna da rai shekaru biyar bayan ganewar asali, idan aka kwatanta da tsawon shekaru 5 na rayuwar mutum 75% ga waɗanda ke fama da ciwon daji . Akwai dalilan da dama akan wannan, wanda ya fito daga ganowa a baya a cikin mutanen da ke fama da ciwon Lynch saboda sun fi kyau game da samun ciwo na ciwon daji na nunawa ga bambancin da ke tattare da ilimin halitta na daban-daban na ciwon daji. Ko ta yaya, wannan labari ne mai ƙarfafawa.
Sources
Ƙungiyar Cutar Canjin Canjin Ciki. Lynch Syndrome. .http: //fightcolorectalcancer.org/prevent-it/risk-factors/lynch-syndrome
Gene Reviews. Abubuwan da ke da ƙwayoyin cuta ba tare da maganin maganin maganin ciwon katako ba. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=hnpcc
Cibiyoyin Nazarin Halittar Kwayoyin Kwayoyin cuta da Rare. Samun shiga: 02/21/16. http://rarediseases.info.nih.gov/GARD/
Lindor NM. Yin wani akwati don kulawa a cikin Lynch ciwo. Cutar da ba daidai ba, 2009 11: 131-32.
Cibiyoyin Lafiya na Ƙasar. Lynch Syndrome. http://ghr.nlm.nih.gov/condition=lynchsyndrome