Kuna iya mamaki dalilin da yasa likitanku zai tsara wani maganin antidepressant don ciwo mai jijiyar zuciya (IBS) idan ba a damu ba. Ko kuwa, kamar yawancin masu fama da IBS, kuna shan wahala daga damuwa ko damuwa tare da IBS, don haka ra'ayin ya kara fahimta, amma kuna sha'awar abin da alamun antidepressant zai iya yi a kan bayyanar IBS .
Sakamakon da zasu biyo baya zai amsa tambaya akan me yasa ake amfani da antidepressants a matsayin magani ga IBS da kuma ilmantar da ku game da nau'in maganin antidepressants wanda aka ba da izini ga marasa lafiya na IBS.
Me ya sa Ana amfani da antidepressants na IBS
Kodayake magungunan magunguna a cikin wannan aji suna da alamun maganin antidepressants, suna da tasiri wanda ba zai iya magance halin da ake ciki ba. An nuna antidepressants don rage damuwa da jin dadin jiki yayin da yake da tasiri a kan tsarin narkewa .
Magungunan likita zasu iya rubuta wani antidepressant zuwa wani haƙuri na IBS, amma wannan an dauke da "lakabi-lakabi" amfani da miyagun ƙwayoyi, domin babu mai maganin antidepressant ya karbi FDA yarda a matsayin magani na IBS. Duk da haka, Cibiyar Kwalejin Gastroenterology na Amirka, bayan binciken da aka gudanar, ya tabbatar da cewa akwai goyon bayan bincike a kan tasiri na biyu na kwayoyi - TCAs da SSRIs - don bayar da shawarar yin amfani da su wajen magance IBS.
Musamman, an gano magungunan antidepressants don samun tasiri mai kyau a kan gurɓataccen motsa jiki da sanyaya ga visceral . An tabbatar da cewa sakamakon amfani da magungunan antidepressants a kan bayyanar IBS shine sakamakon aikin magungunan nan a kan mahaɗin da ke cikin kwakwalwa da ƙuƙwalwa.
Iri iri-iri da ake amfani da su a cikin IBS Jiyya
Magunguna masu amfani da IBS kullum suna fada cikin ɗaya daga cikin ɗalibai masu biyowa:
Tricyclic Antidepressants (TCAs)
Turantan maganin Tricyclic sune tsoffin mazabu na antidepressants. An yi rubuce-rubucen cewa masu amfani da maganin rigakafin tricyclic suna da ciwo da ciwon haushi, kuma suna neman yin haka ta hanyar yin aiki a kan serotonin neurotransmitters da norepinephrine . Wannan jinkirin rage motsi na ƙuƙwalwa yana sa TCA mafi dacewa don maganin cututtukan ƙwaƙwalwa-IBS (IBS-D).
Abin takaici, wannan aikin ( sakamako mai tsauraran zuciya ) wanda zai haifar da jinkirin saukar da hanji na ciki zai iya haifar da sakamako mai lalacewa, ciki har da barci, bakin ciki, hangen nesa, matsalolin jima'i, damuwa, damuwa, ciwon kai da kuma karfin nauyi. Ana ba da takaddun izinin TCA a ƙananan asibiti yayin da ake kula da IBS fiye da lokacin da ake amfani da su a ciki. Wadannan su ne misalai na TCAs waɗanda za a iya ba su izini ga IBS:
- Elavil (amitriptyline)
- Tofranil (imipramine)
- Norpramin (desipramine)
- Aventyl, Pamelor, Allegron (nortriptyline)
Ma'aikata Masu Saukewa na Serotonin Reuptake (SSRIs)
Magunguna masu sukar maganin serotonin (SSRIs) sune magunguna waɗanda aka tsara don ƙara girman siginar neurotransmitter a cikin tsarin mai juyayi, don taimakawa wajen amfani da tasiri a yanayi.
Saboda kawai ƙaddamar da serotonin neurotransmitter, SSRIs yana da rassa masu rinjaye fiye da magungunan antidodiclic. Abubuwa na lalacewa na yau da kullum na cututtukan zuciya, cututtuka, damuwa, da kuma ciwon kai sau da yawa sun rage kamar yadda jikin ya daidaita zuwa magani. Rashin yin tasiri yana haifar da SSRIs mafi kyau ga waɗanda ke shan wahala daga maƙarƙashiyar IBS (IBS-C).
SSRIs na iya haifar da matsalolin haɗari na matsalolin jima'i (asarar jima'i da kuma / ko wahalar samun orgasm) da kuma wadata. Yana da mahimmanci mu tuna cewa mutane daban-daban suna da bambanci kuma mutum zai iya jurewa irin nauyin SSRI fiye da wani.
Wadannan wasu misalai ne na SSRIs da aka tsara:
- Hanyar (Citalopram)
- Lexapro (escitalopram oxalate)
- Prozac (fluoxetine)
- Paxil (paroxetine)
- Zoloft (sertraline)
5-HT3 don takaici
Masu bincike sun dubi magungunan da ke ƙayyade wurare masu karɓar siginonin serotonin da aka sani da masu karɓa na 5-HT3. Mai rikici Lotronex ya shiga cikin wannan rukuni.
Dangane da hadarin mummunar tasiri, FDA ta ƙayyade iyakacin ka'idojin Lotronex. Akwai mai antidepressant 5-HT3, Remeron (mirtazapine). Bayanai sun iyakance ga tasirin Remeron ga IBS kuma sabili da haka ƙila ba za a iya ba da izini ga marasa lafiya na IBS.
Sources
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