Biyan magunguna Lokacin da TSH na al'ada
Yin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin maganin ka. Shin akwai wani abu da za ku iya yi don hana yanayin ciwon maganin ka, ko kiyaye shi daga yin mummunan yanayi? Idan ka tambayi, wasu masu binciken likita zasu watsar da ka, ko kuma gaya maka cewa ba ka da wani zaɓin magani. Sakamakon binciken, duk da haka, ya taimaka wa fahimtar cewa cutar ta Hashimoto-wani cututtukan da ke haifar da hypothyroidism-a gaskiya, za a iya hana shi, jinkirin, ko kuma ya tsaya gaba ɗaya kafin ta cigaba da lalacewar glandar thyroid kuma ya rinjaye hypothyroidism.
A cikin gabatarwa a taron Endocrin Society Endo na 2005, Dokta Ting Chang da abokan aikinsa sun ruwaito akan bada magani na maye gurbin maganin ƙwayar maganin hormone mai suna Levothyroxine (sunayen sunaye sun hada da Synthroid, Levoxyl, da Tirosint) ga marasa lafiya na thyroiditis na Hashimoto. Wadannan marasa lafiya suna da nauyin maganin horroid (TSH ) na al'ada na al'ada , kuma an sanya su a matsayin "euthyroid, ma'ana cewa matakan TSH sun kasance a cikin al'ada na al'ada, duk da haka, sun kamu da maganin thyroid peroxidase (TPO). nuni na autoimmune Hashimoto ta thyroiditis.
Rabin rabin marasa lafiya sun bai wa levothyroxine watanni shida kuma rabin bai karbi magani ba. An gwada gwaje-gwajen maganin karoid da kuma masu daukar nauyin autoantibody kafin da bayan watanni 6. Abubuwan da aka gano sune mahimmanci:
- Wadanda ke karbar levothyroxine sun rage yawan matakan da ake yi , kuma matakan da suka shafi antibody sun karu a wasu daga cikin rukunin da ba a warware su ba.
- Matakan TSH sun ragu a cikin rukunin da ake bi da su, kimanin 0.5 da 2.5 a cikin rukunin marasa biyayya.
Masu binciken sun yanke shawarar cewa maganin levothyroxine na farko zai iya zama da amfani don taimakawa jinkirin cigaban cigaba da yaduwar kawancin Hashimoto.
Wannan ba binciken farko ba ne don nuna cewa maganin rigakafin zai iya kare ci gaba na Hashimoto ko cigaban hypothyroidism.
A cikin rahoton Maris 2001 na mujallar Thyroid , masu bincike na Jamus sun bayar da rahoto game da nazarin marasa lafiya da marasa lafiya a Hashimoto, wanda rabinsa aka bi da su tare da levothyroxine na shekara daya, sauran rabi basu da kyau. Bayan shekara 1, matakan antibody da lymphocytes, wanda shine shaidun kumburi, ya rage muhimmanci kawai a cikin ƙungiyar karbar magani. Daga cikin ƙungiyar da ba a ba da izini ba, matakan da suka shafi rikici sun tashi ko sun kasance daidai.
Masu binciken sun kammala cewa maganin cututtuka na marasa lafiya Huthimroid Hashimoto sun rage nau'ikan alamomi na thyroiditis autoimmune . Sun kuma yi maƙirarin cewa irin wannan magani zai iya dakatar da ci gaba na cutar Hashimoto, ko watakila hana ci gaban hypothyroidism.
A cikin wani binciken, masu bincike na kasar Japan sun gano cewa maganin levothyroxine na iya rage yawan rashin lafiyar Hashimoto ta thyroiditis, kazalika da taimakawa wajen kawar da alamar cutar.
A cikin nazarin marasa lafiya da cutar Hashimoto mai tsananin hankali, wata kungiya ta marasa lafiya sun sami magani na levothyroxine, kuma sauran ƙungiyar ba su sami magani ba. Bayan watanni 15, ƙungiyar ta biyo baya ta karu da matakan T4 kyauta, ƙananan ƙimar TSH, da kuma ragewa a cikin anti-thyroglobulin antibody (Tg-Ab) da kuma maganin anti-thyroid peroxidase antibody.
Girman glander thyroid gland ya rage a cikin ƙungiyar da aka bi, yayin da wadanda basu karbar magani sun sami karuwa a cikin girman giroid , alama don ƙonewa da gland.
Masu bincike sun ruwaito cewa kodayake magani na levothyroxine "yana da muhimmanci a hypothyroid autoimmune thyroiditis marasa lafiya , magani wanda aka nuna ya hana aiwatar da aikin mutum a cikin dabbobin dabba har yanzu yana da rikici a cikin cutar Hashimoto marasa lafiya inda cutar ba ta rushe glandon thyroid gishiri don haifar da hypothyroidism. "
Sai dai sun gano cewa maganin levothyroxine a tantance kiyaye TSH a matakan ƙananan al'amuran yana da tasiri ba kawai a rage yawan matakan autoantibody ba har ma a cikin girman goiter, wanda zai iya hana haɓakawa don kawar da hypothyroidism na sirri.
Kalma daga
Kamar yadda kake gani, akwai wani babban binciken bincike da ya nuna cewa maganin rigakafi tare da levothyroxine na iya zama garanti a cikin mutanen da ke fama da cutar Hashimoto, wadanda ke da matakan TSH na al'ada, amma wadanda kwayoyin cutar sun nuna alamar cutar Hashimoto . Irin wannan magani zai iya taimakawa wasu cututtukan hypothyroidism, a rage jinkirin maganin cututtukan karoid , taimakawa wajen kara tsanantawa da cutar ta asibiti , da kuma hana ci gaban hypothyroidism.
Idan kana da maganin cututtukanka , matakin " TSH " na al'ada "," amma ba a gwada su ba don maganin maganin karoid, dagewa kan samun gwajin TPO da mai aikatawa ya yi.
Idan kana da maganin cututtukan thyroid, matakin TSH "na al'ada" da kuma adadin maganin maganin karoid, ka yi la'akari da neman magani, kuma idan likitanka ba shi da kyau, yi la'akari da gano karin likita ko likita mai mahimmanci .
Sources
En-Ting Chang, Du-An Wu, Dee Pei, Shi-Wen Kuo, Ming-Chen Hsieh. [P2-552] Halin L-Thyroxine Administration a cikin marasa lafiya tare da Euthyroid Hashimoto ta Thyroiditis. Endocrine Society Endo 2005 Abstracts
Thyroid, 2001 Mar; 11 (3): 249-55, "Ɗaya daga cikin shekaru prophylactic jiyya na euthyroid Hashimoto ta thyroiditis marasa lafiya tare da levothyroxine: Akwai wani amfana?"
Duygu Yazgan Aksoy, et. al. "Hanyoyin Prophylactic Thyroid Hormone Sauyawa a cikin Euthyroid Hashimoto ta Thyroiditis" Endocr J (Japan) Vol. 52: 337-343, (2005).