Risks da sakamako masu illa na Celebrex don farfadowa na ƙaura
Celebrex - sunan mai suna celecoxib - wani nau'in anti-inflammatory ko NSAID . Yana aiki ne ta hanyar rikici ƙuƙwalwa a cikin jikin jiki, don haka rage rage zafi. Duk da yake ana amfani dasu da cututtuka , wasu likitoci sun rubuta Celebrex don ƙananan migraines.
Ta Yaya Sakamakon Sabuwar Mawuyaci Daga Tsarin Harshen NSAID?
Celebrex tana nufin wani enzyme a cikin jiki da ake kira COX-2, wanda ke da alhakin ƙonewa cikin jiki.
Ibuprofen da naproxen, a gefe guda, suna ci gaba da maƙalafan COX-2 da COX-1 - don haka an kira su masu ba da zabi NSAIDs. COX-1 shine enzyme wanda ke taimakawa wajen kula da ciki da intestines.
Yayinda NSAID zasu iya rage ciwo da kuma ƙonewa ta hanyar ci gaba da COX-2, su ma zasu iya haifar da rauni ga ciki da na ciki, wanda zai haifar da zub da jini da kuma ulcers gastrointestinal. Ta hanyar ƙaddamar da COX-2, Celebrex yana rage haɗarin matsalar ciki da na hanji.
Shin Celebrex Wanda Ma'aikatan Neurologists Ya Bayyana ga Migraines?
Kodayake ana dauke da NSAID na farfadowa na farko don ƙananan migraines, har yanzu likitocin da yawa sunyi amfani da su wajen rubuta Celebrex. Wannan ya faru ne daga janye wasu masu hanawa COX-2 daga kasuwa, kamar Vioxx (rofecoxib), saboda haɗarsu da matsalolin zuciya.
Yanzu duk NSAIDs, ciki har da Celebrex, suna yin gargadi don kara yawan cututtukan zuciya, kamar ciwon zuciya da bugun jini.
Da aka ce, Celebrex na iya zama wata hanyar maganin ƙwayar ƙwayar cuta, musamman ga mutanen dake fuskantar hadarin cutar NSAID zuwa ciki da kuma hanji. Don tallafawa wannan ka'idar, binciken karamin bincike a 2007 a Singapore Medical Journal ya gano cewa kimanin 400mg na celecoxib ya kasance daidai da 550mg naproxen a rage ƙananan migraines - kuma mai suna Cecoxib ya rage mummunar ciwo fiye da naproxen.
Mene ne wasu tambayoyin da likitanku zai iya yi muku?
Kamar yadda yake tare da kowace magani, yana da mahimmanci don tattauna duk wata hadarin da zai faru tare da likitan ku. Ga wasu misalai na 'yan tambayoyin likitanku zai iya tambayarku:
- Waɗanne magunguna kuke ɗauka? Wasu magunguna suna hulɗa tare da Celebrex ko suna kara haɓaka ga abubuwan da zasu haifar.
- Kuna da wani allergies? Alal misali, kada ka dauki Celebrex idan ka samu ciwon fuka, amya, ko rashin lafiyar da aka yi a NSAID a baya.
- Kuna da matsaloli na likita? Alal misali, kada a ba Celebrex kafin ko bayan zuciya ta tiyata.
- Kuna ciki? Kada a yi amfani da Celebrex a cikin matakan baya na ciki.
Hanyoyi masu mahimmanci na Celebrex
Wadannan suna buƙatar ka tuntuɓi likitanka nan da nan kuma ka hada da:
- Hanyar rashin lafiyar (wahalar numfashi, rufewar bakin ka, kumburi, launi, ko fuska)
- Abun ciki, taushi, ko rashin jin daɗi
- Fuskar jini, baƙar fata, ko tarbiyoyi
- Nausaa ko ƙwannafi
- Cutar zubar da jini
- Ƙimar riba marar iyaka
- Kusawa ko tsaftace ruwa
- Rashin jimawa ko rashin jituwa
- Fatar fata ko ƙyamarwa
- Samun launin fata ko idanu
- "Flu-like" bayyanar cututtuka
- Kuskuren jini ko ruhun jini
Saboda mummunan haɗarin ciwon zuciya da bugun jini tare da Celebrex da sauran marasa aspirin NSAIDs, kamar su ibuprofen da naproxen, yana da muhimmanci a nemi likita nan da nan idan kun fuskanci ciwo mai zafi, matsalolin numfashi, rauni a wani bangare ko gefen jiki, ko maganganu.
Sauran cututtuka masu illa da yawa sun hada da flatulence, cututtukan zuciya, rashin hankali, sanyi bayyanar cututtuka. Yana da muhimmanci a tuntubi likitan ku idan kun lura da duk wani tasiri da ke damunsa, mai jituwa, ko kuma game da ku ko wasu.
Menene ma'anar wannan?
Idan likitanku ya rubuta Celebrex don ƙauraranku, kuna iya ganin shi mafi kyau a cikin ciki fiye da Aleve (naproxen) ko Motrin (ibuprofen).
Sources
Cibiyar Nazarin Harkokin Yammacin Amirka. Ka'idodin Shaidu na Shaida ga Ciwon kai na Migraine a cikin Shirye-shiryen Kulawa na Farko: Cibiyar Nazarin Pharmacological Attacks Attacks. Sake dawowa ranar 2 ga watan Disamba, 2015.
FDA. FDA ta amince da sakonnin farko na celecoxib. Sake dawowa Disamba 2, 2014.
Hawkey CJ. COX-1 da COX-2 masu hanawa. Mafi Amfani da Gin Gastroenterol. 2001 Oktoba; 15 (5): 801-20.
Gidajen E, Burch R, Rizzoli P. Bayanin AHS / AAN na 2012 don kare rigakafi na episodic: taƙaitawa da kwatanta tare da wasu ka'idodin aikin likita na kwanan nan. Ciwon kai . 2012; 52: 930-45 .
Loo CY, Tan HJ, Teh HS & Raymond AA. Randomized, lakabi bude, jarrabawar sarrafawa na celecoxib a cikin maganin wani ƙaura mai zurfi. Singapore Med J. 2007 Sep; 48 (9): 834-9.
Cibiyar Abinci da Drug. (Yuli 9th, 2015). FDA Taimakon Sadarwa ta FDA: FDA ta ƙarfafa gargadin cewa marasa aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) na iya haifar da hawan zuciya ko bugun jini.
Cibiyar Abinci da Drug. Jagoran maganin miyagun ƙwayoyi na anti-inflammatory marasa ciwon steroidal (NSAIDs).