Motsa jiki, auna, da kuma basirar motoci mafi yawancin abin da ya shafi
Matakan cigaba da yawa na cigaba (PPMS) yana shafar mutane da yawa a cikin mutane takwas masu rai tare da ƙwayar sclerosis. Daga nau'ukan iri daban-daban na cutar , PPMS an dauke shi da raguwa.
Ta yaya PPMS Ya Sanya Daga Sauran MS
Mafi yawan al'ada, wanda aka sani da siginar MS (RRMS) , yana nuna mummunan harin da ya biyo bayan lokacin gyarawa inda cutar ba ta ci gaba ba.
Lokacin da ya ci gaba, an ce mutum yana da ci gaba na biyu (SPMS) .
PPMS, ta bambanta, yana ci gaba daga farkon. Mutumin da aka bincikar da PPMS ba shi da alamu na musamman ko raguwa da aka haɗa da RRMS ko SPMS. Maimakon haka, bayyanar cututtuka ta fito da hankali kuma ba su da komai.
Kamar yadda yake tare da wasu nau'o'i na sclerosis da yawa, tafarkin PPMS yana da matukar m, yana shafar kowane mutum daban. Wasu za su iya zama marasa lafiya a cikin 'yan shekarun nan yayin da wasu suna zaman lafiya har tsawon shekaru.
Kwayoyin cututtuka da suka danganci Cord Spinal
Dangane da bayyanar cututtuka, mutanen da aka gano tare da PPMS zasu fuskanci matsalolin matsalolin saboda matsalolin ci gaba (raguwa da ƙetare) na lakabi. Har ila yau, an san shi a matsayin mikilopathy, magungunan na iya hada da:
- Ƙara yawan galihu da ake kira "spastic paraparesis", wanda kafafu zasu fara furtawa, haifar da ƙyallen da ke gani da / ko rhythmic jerkiness
- Wani rauni ko rashin daidaituwa a gefe ɗaya na jiki, wanda aka sani da hemiparesis wanda zai iya shafar kafafunsa, makamai, ko hannayensu
- Ƙara rashin haƙuri (ƙananan ikon yin aikin motsa jiki)
- Rashin ciwo da rashin daidaito na muscle ( ataxia )
Lokacin da cututtukan ta kamu da kashin baya, zai iya tsoma baki tare da fiye da motsi.
Zai iya haifar da lalacewa na jima'i, mafitsara, da kuma aikin jinji. Har ila yau, gajiya yana da mahimmanci tare da wannan kuma duk wasu nau'o'in ƙwayoyin sclerosis.
Kwayoyin cututtuka da suka shafi Brain
Yayin da kashin baya ya zama babban ciwo a cikin PPMS, ƙwaƙwalwar ƙwaƙwalwa za ta iya shafar, musamman ma wani ɓangaren da ake kira cerebellum wanda yake daidaita ma'auni da daidaitawa. An san shi kamar ciwon ciwo na ƙwayar cuta (PCS), cutar ta shafi ɗaya daga cikin mutane 10 da aka gano tare da PPMS kuma zasu iya nunawa tare da:
- Rashin ƙarancin motsi na motsa jiki saboda mummunan buri mai girma
- Rashin sautin muscle (hypotonia)
- Rashin auna (gait ataxia)
- Samun damar yin gyaran motsi (dysmetria) inda mutum ko takalma ko tsinkaye da matsayin da aka yi da hannu, kafa, ko hannu
- Samun yiwuwar yin hanzari da sauri ( dysdiadochokinesia ) irin wannan zanewa a cikin kwan fitila
Kumburi da kuma neurodegeneration sun zama babban ma'anar tushen kwayar cutar da kuma ƙwayar mahaifa a cikin marasa lafiya na PPMS.
Abubuwan da ba a sani ba na PPMS
Yayinda yake da yawa, PPMS zai iya rinjayar wasu sassan tsakiya na tsakiya kamar tsarin kwakwalwa (tsakanin kwakwalwa da kwakwalwa) da kuma cakuda (babban kwakwalwa).
Ana ganin cututtukan cututtuka a kusan kashi ɗaya cikin 100 na mutane tare da PPMS amma zasu iya haɗawa da:
- Matsaloli tare da haɗiye ( dysphagia )
- Dizziness, vomiting, ko tashin hankali
- Ra'ayoyin hanzari , haɗuwa da ido ( nystagmus )
- Raunin hangen nesa ko asarar
- Ayyuka na haɓakawa , ciki har da hasara na ƙwaƙwalwar ajiya, da hankali, ƙwaƙwalwar magana, ko kuma tunani na sararin samaniya
Kalma Daga
Har zuwa kwanan nan, babu kwayoyi da za a bi da PPMS. Magungunan gargajiya na gargajiya, kamar Rebif da Copaxone, suna aiki ta musamman ta rage ƙin ƙonewa da ke RRMS, amma sun tabbatar da rashin amfani da maganin irin ciwon daji a PPMS.
Abin baƙin ciki, abubuwa sun canza. Yanzu muna da magani wanda aka sani da Ocrevus (ocrelizumab) zai iya magance PPMS da kuma sifofin cutar. Gwargwadon Abinci da Harkokin Kiwon Lafiyar Amurka (FDA) ya amince da shi a watan Maris na 2017, an dauke Ocrevus babban mai canzawa na wasan kuma zai iya inganta rayuwar wadanda ke rayuwa tare da wannan samfurin sclerosis.
> Sources
> Ohrbach, R .; Zhao, A .; Wang, Y. et al. "Daidaitawar Ciwon Cututtuka a SPMS da PPMS a cikin Maɗaukaki na Ƙwararrun Ciwon Clinic." PLoS One, 2012; DOI 10.1371 / journal.pone.0045409.
> Cibiyar Abinci da Drug. "Ocrevus (ocrelizumab) Inji." Silver Spring, Maryland; Maris 28, 2017.