TSH shine gwajin mahimmanci don bincikarwa da kulawa da aikinka na Thyroid
Tsarin fassara TSH ba matsala ba ne, saboda haka ba kai kadai ba idan kana yin la'akari da abin da thyroid matakan ke nufin , kuma musamman abin da matakan TSH da ƙananan suke nufi don magani.
Alal misali, mai yiwuwa ka tambayi dalilin da ya sa likitanka ya so ya rage maimakon yin amfani da maganin ka a lokacin da TSH din ya kasance ƙananan, ko, a wata hanya, dalilin da ya sa likita ya ƙara yawan maganin ka a lokacin da TSH ya yi girma.
Tabbatar da cewa, koda yake yana iya komawa baya, duk yana da hankali lokacin da kayi nazarin ilmin halitta na samar da hormone thyroid.
Thyroid Basics
Your gland gland shine samar da hormone thyroid. Lokacin da yake aiki yadda ya kamata, your thyroid ne wani ɓangare na feedback madauki tare da pituitary gland shine yake da cewa ya ƙunshi dama key matakai:
- Na farko, karancinka yana jin matakin da ke jikin kafan hormone da aka saki cikin jini.
- Your pituitary ya bar wani musamman manzo hormone: thyroid stimulating hormone (TSH). Matsayin TSH shine ya motsa karoid don kwantar da hankalin ka.
- A lokacin da kawanka, ko wane dalili-rashin lafiya, damuwa, tiyata, ko tsangwama, alal misali-ba ya iya ba da isasshen hormone na thyroid, pituitary ya gano ƙananan matakan thyroid hormone kuma motsa cikin aikin ta hanyar yin TSH, wanda sai ya haifar da thyroid don yin karin thyroid hormone. Wannan shine kokarin da pituitary ya dauka don tayar da matakan karamar karoid kuma dawo da tsarin zuwa al'ada.
- Idan thyroid ne overactive da kuma samar da yawa ne thyroid hormone-saboda cutar, ko shan ma high wani kashi na thyroid hormone sauyawa kwayoyi-your pituitary ji hankalin cewa akwai da yawa ne hormone thyroid circulating da slows ko ya rufe aikin TSH. Wannan digo a TSH shine ƙoƙari na sake dawowa matakan hormone thyroid zuwa al'ada.
Harshen TSH Levels
Da zarar ka fahimci waɗannan thyroid basics, yana da sauki don gane abin da low TSH da high TSH bayyana game da thyroid ta aiki.
Tunda TSH ta ƙaddamar da matakan hormone da ke riƙe da thyroid kuma yana kiyaye tsarin a ma'auni na al'ada:
- Kyakkyawan TSH yana nuna ka thyroid ne underactive (hypothyroid) da kuma ba yin aiki na samar da isasshen hormone thyroid. A wuce haddi TSH yana aiki don tayar da thyroid don samar da karin thyroid hormone.
- A low TSH nuna your thyroid ne overactive (hyperthyroid) da kuma samar da wuce haddi hormone thyroid. Gwargwadon gwargwadon ƙwayar cuta shine murƙushe TSH don maganin thyroid ba ya samar da karin.
Shin TSH yana da tabbaci?
A lokacin ganewar asali, mafi yawan likitoci sunyi amfani da gwajin TSH don kimanta aikinka na thyroid da kuma ƙayyade mafi kyau duka na magani.
Lura, duk da haka, wasu masu aikin sunyi jin cewa dogara ne kawai a kan TSH, ba tare da yin la'akari da matakan da ke gudana na thyroid ba, kamar yadda thyroxine (T4) ya yi, bazai iya gano karin matsalolin thyroid ba.
Alal misali, T4 kyauta banda TSH an gwada yawanci idan likitan da ake tuhuma da rashin jinƙan kuɗinka wanda ya haifar da cutar daga glandon gwal ko hypothalamus. Haka kuma, idan TSH na al'ada, amma mutum yana da alamun bayyanar cututtuka na hyperthyroid ko hypothyroid, ana iya duba T4 kyauta.
Har ila yau, TSH bai isa ya saka idanu akan hypothyroidism a lokacin daukar ciki , wanda shine dalilin da ya sa aka bari T4 da / ko duka T4.
Dangane da yanayin ƙwaƙwalwar ƙwayar cuta, wasu gwaje-gwaje na thyroid wanda za'a iya kimanta sun hada da triiodothyronine (T3), da baya T3 , da kuma gwajin antibody.
TSH Ranar Range
Babban mahimmanci dangane da TSH zuwa hypothyroidism da hyperthyroidism shine rashin daidaituwa a cikin duniya kiwon lafiya a kan iyakar zane don gwajin TSH.
Matakan da ke ƙasa 0.4 ana dauke da hujjoji na hyperthyroidism, kuma matakan sama da 5.0 ana dauke da yiwuwar shaida ta hypothyroidism, amma wasu masana sun ji cewa wannan tashar yana da zurfi kuma cewa ya kamata a rabu da 0.4 zuwa 2.5mU / L.
Ƙayyade Jiyya Bisa ga TSH
Yayin da ake bi da ku ga hypothyroidism tare da maganin maye gurbin maganin hormone, likitoci za su yi ƙoƙari su gwada ku a cikin zangon "al'ada" na TSH daga 0.3 / 0.5 a kan low-end, zuwa 3.0 / 5.0 a kan babban matsayi.
Don haka, lokacin da ka tafi don dubawa kuma TSH ya zo a kasa na al'ada (wanda ake nufin TSH yana shan damuwa saboda matakan hormone mai ƙwayar rigakafi), likitanku na iya so ya rage yawan kwayar thyroid hormone saboda kun rigaya hyperthyroid . Wannan shi ne saboda matsanancin rikici na TSH (ma'anar haɓakar hawan kuɗin hawan kuɗi) na iya kara yawan haɗarin mutum a kan fibrillation (zuciya arrhythmia) ko osteoporosis.
Kuma idan jarrabawar TSH ta zo a sama da al'ada, wasu likitoci zasu so su kara yawan kwayar thyroid hormone, saboda matakan da ke sama da al'ada ana daukar yiwuwar hypothyroid (underactive).
Kalma Daga
A takaice, jarrabawar TSH shine jarrabawar jini wanda ke amfani da shi don maganin asirin hypothyroidism da hyperthyroidism da kuma kula da maganin maganin hormone (idan an buƙata).
Yayinda yanayin kiwon lafiya, kamar ciki ko kuma asibiti, na iya buƙatar ƙaddara T4 da T3, fahimtar ainihin mahimmancin matakan TSH ko ƙananan mahimmanci don aikinka na thyroid shine ainihin abincin abin da kake buƙatar sani.
Wannan ya ce, idan kana da wasu tambayoyi game da aikin jininka na thyroid, tabbas ka tambayi likitanka.
> Sources:
> Bahn, R., Burch, H, Cooper, D, et al. Hyperthyroidism da sauran dalilai na Thyrotoxicosis: Jagoran Gudanarwa na Amurka Yourroid Association da kuma American Association of Clinical Endocrinologists. Endocrine Practice. Vol 17 No. 3 Mayu / Yuni 2011.
> Braverman, L, Cooper D. Werner & Ingbar's Thyroid, 10th Edition. WLL / Wolters Kluwer; 2012.
> Garber, J, Cobin, R, Gharib, H, et. al. "Ayyukan Gudanar da Harkokin Gudanarwa na Hypothyroidism a cikin Manya: Cikin Shaɗin Ƙungiyar Ƙungiyar Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararruyar Amirka da Ƙungiyar Ƙasa ta Amirka." Endocrine Practice. Vol 18 No. 6 Nuwamba / Disamba 2012.
> Ross DS. (2017). Laboratory kima na thyroid aiki. A cikin: UpToDate, Cooper DS (Ed), UpToDate, Waltham, MA.