Taxoter for Ciwon Magungunan Ciwon Daji - A yaushe Yayi aiki da kuma yadda ya kamata?
Yaya kuma kuma yaushe Taxotere (docetaxel) ke aiki don maganin ciwon kwari na prostate ?
Yaya Taxoter (Docetaxel) Ya Yi aiki?
Taxotre (docetaxel) yayi aiki daidai da magungunan ilimin chemotherapy ta hanyar tarwatsa sassan cell (wanda ake kira mitosis). Tun da kwayoyin cututtuka sune wasu sunadarai da yawa suna rarraba kwayoyin jikinsu a jikin jiki, wadannan kwayoyin sun fi dacewa da aiki na Taxotere kuma, saboda haka, suna mutuwa a manyan ƙimar lokacin da ake amfani da miyagun ƙwayoyi.
Baya ga ciwon daji na prostate, ana iya amfani da Taxotre ga mutanen da ke fama da ciwon huhu na huhu, ciwon nono, ko ciwon daji.
Tarihi - Jigon Magungunan Ciwon Magungunan Ciwon Magunguna
An kawo Taxoter a cikin al'ada na farfadowa da ciwon ciwon sankara bayan da aka buga wani binciken a cikin New England Journal of Medicine a shekara ta 2004 wanda ya nuna cewa Taxotre a hade tare da maganin steroid wanda ya haifar da ingantaccen rayuwa idan aka kwatanta da maganin ƙwayar cuta don ci gaba da ciwon ciwo , mitoxantrone. Har ila yau, Labarin Jaridar New England , ya nuna cewa, wa] annan mutanen da ke tare da Taxotre, sun kasance da kyakkyawar rayuwa da kuma inganta lafiyar cutar. A wannan lokacin, an dauke Taxotere magani ne na zaɓin ciwon ciwon ciwon gurguwar ciwon gurgu a cikin maza waɗanda cutar ciwon karuwanci suka yada bayan karuwanci kuma sun zama magungunan maganin hormone .
Taxoter har yanzu ana la'akari da zabi mai kyau (tare da wasu magunguna da ake nazarin) don amfani da su a cikin maza da ciwon ciwon gurgu na prostate wanda ya zama tushen maganin hormone (farfadowa na cututtukan inrogen.)
Abinda ke nan - Takaddama ga Hormone Early-Cancer Metastatic Ciwon daji
Babbar binciken irin su jarrabawar CHAARTED tsakanin wasu sun canza tsarin kula da cutar kututtuka na farko ga ƙwayar cutar prostate don mutane da yawa. Wadannan cututtuka na iya zama sunadarai a lokacin ganewar asali ko kuma sun zama sunadarai bayan an fara farfasawa ga ciwon gurguwar ciwon gurguwar gida .
Ganin cewa an riga an yi amfani da maganin taxotre ga mutanen da ke da ciwon gurguntacciyar ciwon gurguntacciyar rigakafi waɗanda suka kasance masu tsayayya ga maganin hormonal, yana nuna cewa yin amfani da maganin Taxotre a farkon lokaci - a lokaci guda da aka fara maganin maganin hormonal - yana da amfani a duka ci gaba-kyauta tsira da overall rayuwa. Tabbas, Taxotere na da damuwa na damu da damuwa kamar yadda duk wani maganin miyagun ƙwayoyi, amma wannan, da kuma ci gaba ta amfani da wasu magunguna, alamar ci gaba ne na jin dadin maganin ciwon sankara.
Taxoter for Cibiyar Ciwon Ƙari Ciwon Ƙwayar Ciwo
TAMBAYOYI DA KARANTA YAKE YAKE YAKE YAKE KUMA DA KUMA DA KUMA DA KUMA KUMA. Mutanen da aka bai wa Taxotre a lokacin da aka fara binciken kwayoyin cutar an gano su da mafi kyawun rashin lafiya da kuma rayuwa mafi girma fiye da wadanda aka magance su tare da maganin hormonal kadai. Wani lamari shine cewa maza da suka fi dacewa don wannan magani sune wadanda ke da ciwon "karuwa" mai girma.
Adjuvant Treatment for High-Risk Damarar Ciwo Ciwon Ƙari
Ga maza da ke cike da karuwanci wanda suke da haɗari, ta amfani da Taxoter a cikin wani adjuvant setting (bayanin "idan akwai" ya gano don rage yawan halayen ganyayyun ganyayyun ganyayyaki (spread) na ciwon gurgun ƙwayar prostate.
Wadannan mutane sunyi tare da Taxotere tare da maganin hormonal da radiation , maimakon da maganin hormonal da radiation far kadai. Tabbas, Taxotre yana da wasu illa masu illa wadanda suke bukatar la'akari.
Menene Hanyoyin Hanyoyi
Kamar yadda dukkanin kwayoyi masu kariya yake, akwai nau'o'in illa da dama da zasu iya faruwa a lokacin shan Taxotere. Kuna iya sane da wasu daga cikin waɗannan kamar yadda suke da yawa tare da yawan kwayoyin cutar chemotherapy. Wadannan cututtuka masu gudana sun faru a sama da kashi uku na mutane ta amfani da Taxoter:
- Neutropenia - Ƙididdigar ƙwayar jinin ƙananan jini wanda zai iya haifar da kamuwa da cuta.
- Ananawa - Ƙananan jinin jini wanda zai iya haifar da gajiya tsakanin sauran alamun bayyanar.
- Asarar gashi
- Rage riƙe ruwa
- Diarrhea
- Nausea - Wannan alama ce mafi yawa ana sarrafawa tare da magungunan magunguna na yanzu
- A rash
- Ƙuƙƙan ƙuta
- Canja-canje-canje ya canza
- Hanyar rashin lafiyan - Wannan na kowa ne, kuma magunguna don magance rashin lafiyar cututtuka ana bawa tare da jiko.
Sources:
Fizazi, K., Jenkins, C., da kuma Tannock. Ya kamata Docetaxel ya zama misali na kulawa da marasa lafiya da ciwon ciwon sankara na hormone? Pro kuma contra. Annals na Oncology . 2015. 26 (8): 160-7.
Goodman, A. Docetaxel Haɗa tare da Hormone Far farkawa Rayuwa a Advanced Ciwon Ƙari Ciwon daji. ASCO Post . http://www.ascopost.com/issues/may-25,-2015/docetaxel-combined-with-hormone-therapy-extends-survival-in-advanced-prostate-cancer.aspx.
James, N., Sydes, M., Clarke, N. et al. Adadin docetaxel, zoledronic acid, ko duka zuwa layin farko na hormone farfadowa a ciwon daji na jini (STAMPEDE): rayayye sakamakon sakamako, multiarm, multistage, dandamali gwajin gwagwarmaya. Lancet . 2015 Dec 21. (Epub gaban bugu).
Martel CL, Gumerlock PH, Meyers FJ, et al. Labarun yau da kullum a gudanar da cutar hormone. Ciwon daji ya yi wa Rev. 2003; 29: 171-187.
Cibiyar Cancer ta Kasa. Nazarin da aka ba da tallafin NIH ya nuna yawan ci gaba a cikin maza da ciwon gurguntacciyar ciwon karuwanci wanda ke karbar chemotherapy lokacin farawa na hormone. http://www.cancer.gov/news-events/press-releases/2013/E3805.
Tannock IF, de Wit R, Berry WR, et al. Docetaxel da prednisone ko mitoxantrone da prednisone na ci gaba prostate cancer. N. Engl. J. Med. 351 (15): 1502-12.