Yana da kariyar rikici, don haka kiyaye waɗannan abubuwa a hankali
Glucosamine shine karin karin abincin da ake amfani da ita lokacin da ake amfani dasu don sauƙaƙe ciwon gwiwa na osteoarthritis (OA). Da zarar ya zama sananne, amfani da shi yanzu yana raguwa, mafi yawa saboda sakamakon da ya haɗu da ya danganci amfanar wannan ƙarin.
Idan kun dauki glucosamine ko kuna la'akari da gwaji na ƙarin (a karkashin kula da likitanku, haƙiƙa) a nan akwai sanarwa biyar don tunawa:
Tidbit # 1: Glucosamine An Halitta A Cikin Gwaji
Glucosamine abu ne na halitta (wanda ake kira da amino sugar) wanda aka samo shi a cikin guringuntsi mai mahimmanci da gwanin gine-gine , dukansu suna kwantar da gadon ku. A cikin osteoarthritis, guringuntsi a cikin kwakwalwarka ya ɓata, yana haifar da ciwo da haushi. Cikin ciwon zai iya zama mawuyacin hali kamar yadda guringuntsi ya zama abin da ya sa haka ƙasusuwan sun fara kwashewa.
Tidbit # 2: Glucosamine ba a yi hukunci a matsayin likita ba
A Amurka, ana sayar da glucosamine a matsayin kari na abincin. Wannan yana nufin cewa Hukumar Kula da Abinci da Drugke ta Amurka (FDA) ta kayyade shi a matsayin abincin abinci, maimakon tsayayya da takardar magani ko magunguna.
Tare da wannan, kodayake glucosamine wani nau'i ne na jiki na guringuntsi, ba yana nufin cewa karbar shi yana da lafiya. A gaskiya ma, glucosamine na iya canza matakan jini kuma zai iya hulɗa tare da wasu magunguna kamar jini-thinner Coumadin (warfarin).
Kamar yadda kullun, tabbatar da kawai yin amfani da miyagun ƙwayoyi, ciki har da ƙarin kayan aiki, a ƙarƙashin kula da likitan ka.
Tidbit # 3: Glucosamine Ba Zai Yi Kyau Ga Kwancen Osteoarthritis ba
Yayinda binciken bincike a kan gwangwani Kwayoyin sun gano cewa glucosamine na iya bunkasa rudani na guringuntsi da kuma kawar da matakan ƙananan ƙwayoyin cuta waɗanda ke haifar da lalacewa na ƙwayar cututtuka, wannan bayanan binciken ba a fassara shi zuwa asibiti ba.
Nazarin farko da aka yi a Amurka wanda yayi nazarin sakamakon glucosamine a kan gajeren lokaci (a kan gwiwa osteoarthritis) an kira shi gwajin GAIT (Glucosamine Arthritis Intervention Trial).
A GAIT, fiye da 1500 masu halarta tare da gwiwar osteoarthritis an ba da izini zuwa ɗaya daga cikin kungiyoyi biyar masu jiyya:
- Glucosamine a 500mg sau uku a rana (total 1500mg kowace rana)
- Chondroitin sulfate (Har ila yau, karin abincin abinci da na halitta abu na guringuntsi) a 400mg sau uku a rana (1200mg kowace rana)
- Glucosamine da chondroitin sulfate a hade
- Celecoxib (mai maganin kare kumburi, ko NSAID) a 200mg kowace rana
- A placebo (wani abu da yake aiki)
Sakamako daga nazarin GAIT ya nuna cewa masu halartar bikin Celexib na NSAID sun sami gagarumin taimako na jin zafi da wuribo.
Babu wani bambanci tsakanin sauran jiyya da aka gwada da kuma placebo.
Kodayake, a cikin wa] anda suka ha] a da masu karatu da ciwo mai tsanani, glucosamine tare da sulfate na chondroitin sun ba da taimako mai tsanani idan aka kwatanta da placebo. Masu bincike na binciken, duk da haka, sun ce saboda girman wannan rukuni ya kasance karami, wannan bincike ya kamata a yi la'akari da farko kuma yana buƙatar tabbatarwa a binciken bincike na gaba.
Ga mahalarta tare da ciwon gwiwa gwiwa (kamar yadda tsayayya da matsakaici ko mai tsanani) glucosamine da chondroitin sulfate tare ko kuma kadai bai samar da taimako mai zafi ba.
Tidbit # 4: Akwai nau'i biyu na Glucosamine
Yana da muhimmanci a lura cewa za'a iya ba glucosamine tare da nau'i biyu na gishiri, hydrochloride ko sulfate. Nazarin GAIT (aka ambata a sama) ya yi amfani da glucosamine hydrochloride. Abin sha'awa, binciken da ya nuna wasu yiwuwar, albeit kananan, amfani da glucosamine sulfate su bi da osteoarthritis maimakon glucosamine hydrochloride.
Alal misali, babban binciken a cikin Jarida ta Duniya na Clinical Practice yayi nazari kan marasa lafiya 3000 da osteoarthritis na gwiwa a cikin gwaji 19.
Mawallafin wannan binciken sun kammala cewa glucosamine hydrochloride ba amfani a rage rage (kamar jarrabawar GAIT).
Duk da haka, babban allurai na glucosamine sulfate (1500mg a kowace rana) na iya samun sakamako-gyare-gyare lokacin da aka ɗauki fiye da watanni 6. Sakamakon gyaran haɓaka yana nuna cewa glucosamine sulfate na iya inganta ikon mutum yayi amfani da gwiwa (ko gwiwoyi) tare da osteoarthritis.
Tidbit # 5: Abin da Kwalejin Kwalejin Rheumatology na Amurka ta Glucosamine
A cewar Cibiyar Harkokin Rheumatology na Amirka, ko ACR, mutanen da ke fama da ciwon osteoarthritis kada su yi amfani da glucosamine. Duk da haka, an bayar da shawarar wannan "yanayin," kamar yadda ACR ta gane cewa amfani da glucosamine har yanzu yana da rikici.
Maimakon haka, ACR ta bada shawarar da za a biyo baya don maganin gwiwa OA:
- Tylenol (acetaminophen)
- SAIWAI (ko ta bakin ko a fata)
- Ultram (Tramadol)
- Corticosteroid injections a cikin sarari sarari
Kalma Daga
Duk da yake alkawarinsa na glucosamine a matsayin madadin magungunan gadon osteoarthritis bai yi daidai ba, wasu mutane har yanzu suna daukar shi kuma suna ganin yana aiki a gare su.
A ƙarshe, ba tare da la'akari da tsarin kulawarka na yau da kullum don gwiwar osteoarthritis ba, yana da muhimmanci a ga likita don biyan bi da bi. Wannan hanyar za ku iya canza hanyoyin kwantar da hankulanku yayin da lafiyar ku ta bunƙasa kuma bincike ya gudana.
> Sources:
> Hochberg MC et al. Kwalejin Kwalejin Rheumatology na Amurka na 2012 2012 game da amfani da marasa lafiyar kwayoyin halitta da maganin cututtuka na pharmacologic in osteoarthritis na hannun, hip, da gwiwa. Arthritis Care Res (Hoboken) . 2012 Apr, 64 (4): 465-74.
> Jerosch J. Hanyoyi na glucosamine da chrondroitin sulfate a kan guringuntsi metabolism a OA: Outlook a kan sauran masu cin abinci na gina jiki musamman omega-3 acid fat. Int J Rheumatol . 2011; 2011: 969012.
> Cibiyar Kasa ta Kasa ta Kasa da Kwarewa. (2014). Glucosamine da Chondroitin don Osteoarthritis.
> Wu D, Huang Y, Gu Y, Fan W. Ayyukan daban-daban na glucosamine don maganin osteoarthritis: wani zane-zane na baƙi, da makafi guda biyu, da gwaji. Int J Clin Pract. 2014 Yuni, 67 (6): 585-94.