Raunin Rare da ke Shafan Tsarin Mulki
Ciniki na Costello wata cuta ce mai wuya wanda ke rinjayar tsarin da yawa na jiki, haifar da gajeren lokaci, yanayin halayen halayyar jiki, girma a cikin hanci da baki, da matsalolin zuciya. Dalilin rashin lafiyar Costello ba a san shi ba, kodayake maye gurbin kwayoyin da ake zargi. A shekarar 2005, masu bincike a asibitin DuPont a Delaware (US) sun gano samfurin maye gurbi a cikin HRAS a cikin 82.5% na mutane 40 da Costello ciwon da suka yi karatu.
Kusan kimanin rahotanni na Costello kimanin 150 ne a cikin wallafe-wallafen likita a duniya, don haka ba a bayyana yadda sau da yawa yawan ciwo yana faruwa ko wanda zai iya shafar shi.
Cutar cututtuka
Magunguna bayyanar cututtuka ga Costello ciwo shine:
- wahalar samun nauyi da girma bayan haihuwar, wanda ke haifar da ɗan gajeren lokaci
- m fata mai laushi a kan wuyansa, hannuwan hannu, yatsunsu, da ƙafãfun kafa (cutis laxa)
- marasa ci gaban daji (papillomata) a kusa da bakin da nostrils
- siffar halayen fuska irin su babban kai, kunnuwa mai sauƙi da manyan, lobes lobaye, ƙananan lebe, da / ko fadin hanyoyi
- ragawar tunani
- thickened, bushe fata a hannun da ƙafa ko makamai da kafafu (hyperkeratosis)
- Abubuwa masu mahimmanci na yatsunsu.
Wasu mutane na iya ƙuntata motsin motsi a kan kusoshi ko kuma ƙarfafa ƙwanƙwara a gefen idon. Mutum tare da ciwo na Costello zai iya zama ciwon zuciya ko cututtukan zuciya (cardiomyopathy).
Akwai babban halayen ci gaba da ciwon tumo, duk da ciwon daji da marasa ciwo, wanda ke hade da ciwo.
Sanin asali
Sakamakon ganewar rashin lafiyar Costello yana dogara ne akan bayyanar jiki na yaron da aka haifa tare da cutar, da sauran alamomin da zasu iya kasancewa. Yawancin yara tare da ciwo na Costello suna da wahalar ci abinci, da kuma samun karfin jiki da girma, saboda haka wannan zai bada shawara akan ganewar asali.
A nan gaba, gwajin kwayoyin ga maye gurbin mutun da aka sani tare da cututtukan Costello zai iya amfani dashi don tabbatar da ganewar asali.
Jiyya
Babu magani na musamman game da ciwo na Costello, saboda haka likita ta mayar da hankali akan bayyanar cututtuka da kuma rashin lafiya. An bada shawarar cewa duk mutanen da ke tare da ciwon Costello sun sami kimantawa na likitan zuciya don neman zuciya da cututtukan zuciya. Harkokin jiki da na sana'a zai iya taimakawa mutum ya kai ga iyalanta. Kulawa na tsawon lokaci don ci gaba da ciwon sukari, maganin launi ko matsalolin kothopedic, da kuma zuciya ko matsa lamba na jini yana da muhimmanci. Mutum tare da ciwon Costello za a rinjayi ta wurin ciwon matsalolin zuciya ko ciwon sukari , don haka idan lafiya, mutanen da ke fama da ciwo zasu iya samun rayuwa ta yau da kullum.
> Sources:
> Kids Costello. Game da ciwo na Costello.
> Gripp, KW, et al. (2005). Ra'ayin maye gurbin HRAS a Costello ciwo: Genotype da zumuntar siffofi na phenotype. American Journal of Medical Genetics.
> Lin, AE, et al. (2002). Ƙarin jerin abubuwan ciwon hauka na nakasar zuciya a Costello. Jarida na Amirka na Magunguna na Genetics, 111 (2), shafi na 115-129.
> Moroni, I., et al. (2000). Ciniki na Costello: Cutar da ke ciwon ciwon daji? Clin Dysmorphol, 9 (4), shafi na 265-268.
> Ƙungiyar Ƙungiya ta Ƙananan Raunuka. Costello Ciwo.
> Pascual-Castroviego, I., et al. (2005). Costello ciwo: Gabatar da wani akwati tare da biyo bayan shekaru 35. Neurologia, 20 (3), shafi na 144-148.