Lymphoma Hodgkin (HL) wani ciwon daji ne na fararen jini wanda zai iya rinjayar matasa masu haihuwa. A gaskiya ma, ko da yake HL tana wakiltar kimanin kashi 10 cikin 100 na dukan lymphomas , yana daya daga cikin subtypes da aka fi sani da lymphoma da aka fi sani da a lokacin daukar ciki. Wannan shi ne saboda gaskiyar abin da HL ya faru daidai da shekarun haihuwa.
Tsayawa Fetus Safe
Wasu daga alamu da bayyanar cututtuka daga HL, irin su gajiya da rashin ƙarfi na numfashi, na iya samuwa tare da alamomi da alamomin da aka gani a yayin daukar ciki, wanda zai iya magance matsalolin, amma ana yin aikin HL don samar da cikakkun bayanai don jagorancin gudanarwa yayin iyakance hadarin ga tayin.
Alal misali, lokacin da aka yi wa rayukan kwakwalwa, an rufe ciki don kiyaye lafiyar jaririn. Don kimanta ciki, MRI da duban dan tayi za a iya yi. Za'a iya aiwatar da kwayar halitta mai laushi mai yatsa a lokacin da ake ciki idan an buƙata.
Gudanarwa na HL a lokacin daukar ciki yana nufin daidaita daidaituwa da magani da kuma rage mummunan cutar ga jariri mai tasowa. Yawancin mata masu ciki da HL da aka bincikar su a lokacin daukar ciki suna farkawa. Haɗuwa da ilimin chemotherapy irin su ABVD an samu nasarar gudanar da shi a farkon farkon watanni. Nazarin binciken abubuwan haifuwar haihuwa a cikin iyayen da aka yi wa HL suna karfafawa, ba su nuna bambanci a matsayin nauyin haihuwar haihuwa ko kuma rashin lafiyar jiki ba idan aka kwatanta da jarirai da aka haifa ga iyaye mata ba jurewa ba. A cikin matan da aka zaɓa, za a iya jinkirta magani har sai an ba da jaririn lafiya.
Bayanan haihuwa Bayan Jiyya ga Hodgkin Lymphoma
A cewar wani labarin da aka wallafa a cikin watan Nuwamba 2011 na "Haematologica," wani abu da ake kira gazawarsa na ovarian-wanda ya faru a farkon asibiti-na iya faruwa a cikin kashi 5 zuwa 25 cikin dari na mata masu shan magani a cikin shekaru 30.
Haɗarin rashin haihuwa ya ƙaru tare da ƙaddarawa ƙwayoyin wasu chemotherapies da ake kira alkylating jamiái.
Har ila yau, an danganta magungunan ƙwayar cutar don lalata ovaries. Wurin da ake kira myeloablative farfesa ya ƙara haɗari cewa mace ba za ta iya yin ciki ba bayan magani. Irin wannan farfitawa yana amfani da kwayar cutar chemotherapy mai tsanani wanda ya kashe kwayoyin jikinsu a cikin kututtukan fata, ciki har da kwayoyin cutar kanjamau.
Har ila yau, yana rage yawan ƙwayar jini a jikin kututtukan jini, wanda zai iya taimakawa wajen ciwo mai tsanani. Lokacin da aka yi amfani da mieloablative chemotherapy, ana bin wannan sauƙi ne ko ɓawon ƙwayar jini don sake mayar da aikin karfin mahaifa.
Wani binciken da Meirow da abokan aiki suka yi sun nuna cewa rashin cin zarafin ovarian da aka ba shi ya fi sau da yawa a cikin mata fiye da shekaru 30, da kuma cewa tsarin kula da lafiyar magunguna da kashi na musamman na irradiation na pelvic sune dalilai masu dacewa a cikin haihuwa. Musamman mai guba ga nau'in ovarian shine alkylating jamiái.
Mafi yawan nazarin sunyi nazarin haihuwa a cikin marasa lafiya da ke bin HL magani. Ɗaya daga cikin binciken shi ne cewa an tsara tsarin tsarin BEACOPP a matsayin mafi girma da ya shafi mafi girma na amorrhea fiye da tsarin ABVD. Aminiya na biyu ya bayyana cewa babu zubar da jini a cikin mace wanda ke yin haila amma daga bisani ya dakatar da haila na wata uku ko fiye da watanni - kuma rashin tsawon lokaci ba shi ne saboda haifa ba, hayar da jariri, maye gurbi tare da maganin rigakafi na yau da kullum (magunguna) kwayoyi, ko menopause.
Abubuwan da aka tsara a sama sune:
- BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, da prednisone, inda masu amfani da alkylating su ne cyclophosphamide da procarbazine)
- ABVD (doxorubicin, vinblastine, dacarbazine, da kuma bleomycin, inda wani alkylating wakili ne dacarbazine)
Duk da yake maganin zamani na yaudara ne akan HL, zasu iya daukar nau'i a kan gonads da ovaries musamman. Ga likitocin da ke nazarin wannan sabon abu, ana danganta yanayin a matsayin "ƙwayar cutar chemotherapy raguwar yankakken ovarian," ko chDOR.
ChDOR yana dauke da ƙananan ƙwai a cikin ovaries mata amma kuma zai iya tasiri akan cigaban ƙwayoyin da ke ciki. Hanyoyin cututtuka sun hada da amintattun digiri da rashin haihuwa. Cikakken ƙananan ƙwayoyin ciki a cikin ovaries zai iya haifar da abin da ake kira lalacewar ovarian da ba a taɓa yin ba, wanda aka fi sani da hasara na aikin ovarian kafin shekaru 40.
Akwai wasu shaidun cewa gwamnati na analogues na homodotropin (GnRH-a) a lokacin yaduwar cutar na iya taimakawa kare ovaries. Ma'anar yadda za'a iya aiki wannan, duk da haka, har yanzu ba a fahimta ba.
Hanyar haihuwa
Mace marasa lafiya ba su da tasirin haihuwa daga farfadowa, ko dai. Kwararrun suna mai saukin kaiwa ga maganin ciwon ciwon daji a duk matakai na rayuwa. Bisa ga binciken da Jahnukainen da abokan aiki suka yi, matasa maza da suka tsira daga cutar kanjamau sun kusan rabin kamar yadda 'yan uwan su suka yi ciki. Wannan takarda ta bayyana farfadowar radiation ga gwaji da kuma babban jimillar yawan ma'aikatan alkylating kamar manyan abubuwan dake rage yiwuwar haihuwa.
Kalma Daga
Yanayin magani na ciwon daji da kuma adana takin gargajiya yana karuwa. Sabobbin maganin cutar kanjamau suna fitowa da yawa, don haka duka maganin lymphoma da kuma kula da illa mai tasiri, ciki har da rashin haihuwa, suna cikin tsarin juyin halitta akai-akai. Yi magana da likitan ku don sanin abin da mafi kyawun hanyar kulawa ku.
Sources:
Harel S, Ciki C, Poirot C. Gudanarwa na haihuwa a marasa lafiya bi da su don lymphoma na Hodgkin. Haematologica . 2011; 96 (11): 1692-1699.
Hutchings M. Yaya PET / CT ya taimaka wajen zaɓar farfadowa ga marasa lafiya da lymphoma Hodgkin? Hematology Am Soc Hematol Ilimin Ilimi. 2012; 2012: 322-7.
Meirow D, Biederman H, Anderson RA, Wallace WH. Rashin guba na chemotherapy da radiation a kan haifuwa mata. Clin Obstet Gynecol. 2010; 53: 727-39.